Filetype
Background: Adrenaline (ADR) is a cornerstone of advanced life support (ALS) in cardiac arrest (CA), although its neurologically favourable survival outcomes remain unclear. ADR increases coronary perfusion pressure (CPP), with levels >15 mmHg associated with successful defibrillation. This study aimed to elucidate the relationship between ADR, myocardial microvascular blood flow, and resuscitatio
Despite the considerable amount of research devoted to speech act theory, relatively little attention has been paid to the cognitive foundations underlying different speech act classes. This article addresses this gap by introducing a framework of cognitive dimensions associated with the performance of expressives, directives and assertions. Drawing on empirical data, we argue that each class requ
Introduction: Adult acquired flatfoot deformity (AAFD) is a disabling condition that may require complex surgical treatment. Little is known about the incidence of AAFD in the general population and specifically of AAFD requiring specialist care. We aimed to describe the incidence of AAFD referred to specialist care in the Swedish general population. Methods: We conducted a nation-wide epidemiolog
In recent years, injectable cryogels have been frequently used in various biomedical applications such as tissue engineering, drug delivery, therapeutics, therapy, cell transplantation and immunotherapy. Cryogels, one of the biomaterials with injectable 3D scaffold structures, have important properties such as biocompatibility, physical resistance, macropore and sensitivity. In addition to being b
Apolipoprotein E (APOE) is distributed across various human tissues and plays a crucial role in lipid metabolism. Recent investigations have uncovered an additional facet of APOE's functionality, revealing its role in host defense against bacterial infections. To assess the antibacterial attributes of APOE3 and APOE4, we conducted antibacterial assays using Pseudomonas aeruginosa and Escherichia c
Context: Peptidylglycine-α-amidating monooxygenase (PAM) is a critical enzyme in the endocrine system responsible for activation, by amidation, of bioactive peptides. Objective: To define the clinical phenotype of carriers of genetic mutations associated with impaired PAM-amidating activity (PAM-AMA). Design: We used genetic and phenotypic data from cohort studies: the Malmö Diet and Cancer (MDC;
Objectives Peak exercise systolic blood pressure (SBP) is associated with future cardiovascular disease (CVD) and mortality. We aimed to evaluate the predictive value of different SBP patterns at the end of exercise with these outcomes. Methods We studied 6329 adults (45% women) referred for exercise testing, with test duration of 6-14 min, maximal effort and valid SBP measurements at the end of e
Aims: Our aim was to investigate the psychometric properties of the health assessment instrument EQ-5D-5L in OHCA survivors.Methods: We included survivors from the Targeted Hypothermia versus Targeted Normothermia after OHCA (TTM2) trial, who completed EQ-5D-5L at 6 months. Confirmatory factor analysis was used to evaluate the hypothesised unidimensional latent structure of EQ level sum score (EQ Aims: Our aim was to investigate the psychometric properties of the health assessment instrument EQ-5D-5L in OHCA survivors.Methods: We included survivors from the Targeted Hypothermia versus Targeted Normothermia after OHCA (TTM2) trial, who completed EQ-5D-5L at 6 months. Confirmatory factor analysis was used to evaluate the hypothesised unidimensional latent structure of EQ level sum score (EQ
Protests against various transition projects, including both infrastructure and policy changes, are not uncommon and have been observed in diverse contexts. However, protests specifically against Bus Rapid Transit (BRT) implementation remain understudied. This study examines the local media debate surrounding a BRT project in Örebro, Sweden, with a focus on how proponents and opponents use argumen
In Westerhus on the island of Frösö in Jämtland the childhood was a stressful period with high mortality. In this study the living conditions of the children are discussed on the basis of the age distribution of infants, the prevalence of enamel hypoplasia and the tooth size of deciduous and permanent teeth. Gejvall’s age distribution of infants dying in the neonatal and the postneonatal periods w
This article presents a taxonomy of altered states of consciousness, primarily based on their central phenomenological features. Following taxonomic principles and a modified Delphi methodology, a multidisciplinary, international group identified eight distinct phenomenological/behavioral states (some with subcategories): proto and transitional, delirium, minimal to no awareness, experiential deta
Solar drying technologies have emerged as efficient and user-friendly solutions for food drying processes, particularly in regions with limited access to electricity and high post-harvest losses. These technologies offer a sustainable alternative to conventional drying methods. However, one of the key challenges limiting their effectiveness is the non-homogeneous airflow inside the drying chamber,
This work presents a new approach to the autotuning strategy for controlling pH in raceway reactors, based on classical relay-based autotuning principles. A relay applied to reference method is proposed that allows seamless integration into existing control loops without the need for manual recalibration across seasons or operator intervention. Two different models were identified: first-order wit
The recycling and reuse of trace uranium from spent nuclear fuel is of great significance for the safety management of the nuclear fuel cycle. However, stabilization of low-valent uranium has always been a challenge due to the ultraoxidizable nature of uranium ions, which remains relatively uncharted territory in spent fuel treatment. In the current study, U4+ was immobilized in Cs2UCl6 single cry
This report examines the evolving political discourse in Ireland in the lead-up to the 2024 local, general and European elections, focusing on the potential rise of far-right populism. Traditionally dominated by centrist parties, and with an increasingly progressive trajectory of referendums, Ireland has long been viewed as an exception to the European trend of far-right mobilisation. However, rec
PrologMikrovågs-hypertermi och strålbehandling (1980–1990)Min tidiga forskning inom medicinsk strålningsfysik ledde till kombinerad behandling av bröstcancer-recidiv med mikrovågsinducerad hypertermi och lågdos strålning (30 Gy). Kliniska försök inleddes med patienter som tidigare fått full stråldos (60 Gy). Utrustningen visades upp för kung Carl XVI Gustaf och drottning Silvia på Forskningens DagThis story has its origin in my presentation at the 1983 Research Day in Lund, to HM King XIV Gustav on our development of microwave-induced hyperthermia treatment of breast cancer recurrence, which brought me together with Professor Leif G. Salford, whose presentation was next to mine. Shortly before the turn of the millennium, Leif Salford initiated a clinical trial "Brain Immune Gene Tumour
