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This paper integrates the concepts of first and second stories as well as Symbolic Interactionism and provides a framework that emphasizes the local rationality of practitioners and the social construction of meaning within their organizations. This paper will first consider some of the assumptions that characterize today’s safety discourse(s) because they inform how CS works with clients. What Sy
Immune checkpoint blockade (ICB) therapy can restore T cell function in tumors, but not all patients benefit, and the mechanisms behind this remain unclear. In this study, we used patient-derived organotypic (PDO) cultures from metastatic melanoma to examine transcriptomic and cellular changes following ex vivo T cell stimulation. Genomic and transcriptomic features were preserved during PDO forma
Lake water storage variations on the Tibetan Plateau (TP) serve as crucial indicators of regional hydrological dynamics and climate changes, providing more comprehensive insights than discrete measurements of lake area or water level alone. While accurate bathymetric data is fundamental for quantifying lake water storage, conventional bathymetric surveys are often constrained by logistical challen
Daniel Suhonen och Tony Johansson från den fackliga tankesmedjan Katalys vill i Di Debatt 8 december dölja det uppenbara: efterkrigstidens socialdemokratiska regleringar av den svenska kapitalmarknaden höll tillbaka svensk tillväxt i ett halvt sekel, skriver Lars Jonung. professor emeritus, Lunds universitet.
This book comprehensively explores various methodologies and sources used to understand and improve road safety. It delves into the advantages and disadvantages of primary data sources such as police accident records, statistical methods for data analysis, in-depth investigations, healthcare data, self-reporting of behavior, data from automated vehicles, naturalistic driving/cycling/walking studie
Enabling journeys from door-to-door is an essential part of attracting people towards public transport and away from the private car. Facilitating such journeys requires comprehensive and integrated planning across modal and spatial boundaries. Public transport governance, however, is often constrained by fragmented, multi-level structures and regulatory barriers that limit the ability of responsi
Background Low-grade systemic inflammation is linked to abnormal spirometry. Impulse oscillometry (IOS) is sensitive in detecting peripheral airway dysfunction, but inflammation in relation to IOS is poorly studied. The objectives of the present study were to analyse associations between C-reactive protein (CRP), blood eosinophils (B-Eos), blood neutrophils (B-Neu), blood lymphocytes (B-Lym), bloo
Tax incentives can be a policy instrument to fund the arts and culture. Such incentives must meet certain rules and principles, including, for EU Member States, EU requirements. In addition, various other aspects must be taken into account in the appreciation of tax incentives as a cultural funding instrument. This includes, on the one hand, notions of fairness, concerns about ‘philanthrocapitalis
While fiscal policy making in the EU is in the hands of national governments, it is to be carried out in accordance with commonly agreed rules: the Stability and Growth Pact (SGP). The SGP originates in the understanding that uncoordinated fiscal policy produces cross-border effects that can harm the functioning of the Economic and Monetary Union. For member states with an excessive deficit, that
Purpose – This paper concerns an integrated life cycle assessment (ILCA) comparing daylighting retrofit solutions for an existing sports hall, currently relying only on electric lighting. Daylight quality, environmental impact and financial aspects are generally independently considered, leading to suboptimal decisions when all aspects are considered together. By taking the sports hall as an examp
Study Region 103 FLUXNET2015 flux towers distributed across diverse climatic and ecological regions. Study Focus Accurate estimation of evapotranspiration (ET) is critical for understanding regional ecohydrological processes. Physically based models such as the Penman-Monteith-Leuning (PML) model are robust but often constrained by fixed parameterization schemes, while data-driven approaches such
Background: Collider bias is often considered a potential explanation when the association between obesity and disease diagnosis differs from that with disease outcome, as seen in the “obesity paradox.” For prostate cancer (PCa), in particular localized PCa, an “inverse” obesity paradox has been observed, where body mass index (BMI) is negatively associated with diagnosis (hazard ratio [HR] ~0.9 p
This is the first part of a work devoted to the study of the set of integer solutions to a system of inequalities determined by homogeneous forms. According to the heuristics that the number of such solutions should match the volume of the set of real solutions, sharp estimates for the volume of the semialgebraic domain under consideration are established. These estimates are expressed as a functi
Introduction: Familial risk of lung cancer (LC) is at the level of many common cancers (ca 2.0) but as cigarette smoking is the main cause of LC, it has remained undefined to what extent smoking contributes to the familial risk. We take advantage of the natural experiment of divorce. In Sweden, it has been customary that children stay with their mother after divorce. We thus hypothesize that only
An important step in understanding the formation and evolution of the nuclear star cluster (NSC) is to investigate its chemistry and chemical evolution. Additionally, exploring the NSC’s relationship to the other structures in the Galactic center and the Milky Way disks is of great interest. Extreme optical extinction has previously prevented optical studies, but near-IR high-resolution spectrosco
Background: Although physiological reflux is seen in nearly all newborns to varying degrees, symptoms can be severe and cause gastroesophageal reflux disease (GERD). In preterm infants, one symptom that is often attributed to GERD is apnea and associated cardiorespiratory events, such as bradycardia and oxygen desaturation. Although the relationship between GERD and apnea, bradycardia, and desatur
Turbulent heat transfer over rough surfaces is crucial in natural and industrial processes, yet it has received less attention than that of momentum transfer. Recently, research in this field is rapidly growing, driven by advancements in computational methods, the role of surface roughness in meteorology, and the growing use of Additive Manufacturing technologies for energy and thermal management
Understanding the initiation, propagation and evolution of water injection-induced fractures is essential for geo-energy applications. Hydromechanical stimulation experiments were conducted in a deep borehole drilled into crystalline bedrock to gain insights into these processes, involving simultaneous in-situ measurements of three-dimensional fracture displacements, injection flow rates, and wate
