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A storyline approach : integrating comprehensive, interdisciplinary research results to create narratives – in the context of the net-zero target in Germany
With the amendment to the German Climate Change Act in 2021, the Federal Government of Germany has set the target to become greenhouse gas neutral by 2045. Reaching this ambitious target requires multisectoral efforts, which in turn calls for interdisciplinary collaboration: the Net-Zero-2050 project of the Helmholtz Climate Initiative serves as an example of successful, interdisciplinary collabor
Take away : Avimplementering av etablerade arbetssätt när det finns bättre alternativ
Avimplementering är en nödvändig och utmanande process inom socialt arbete. Den innebär att ta bort eller avsluta användningen av metoder eller praxis som är ineffektiva, skadliga eller inte längre kostnadseffektiva. Artikeln baseras på en studie i Sverige av implementering av två evidensbaserade metoder. Forskarna har genomfört en survey, gjort litteraturstudier och fallstudier. Resultaten visar
Despite antiretroviral therapy (ART) rollout, most cases of tuberculosis among people with HIV in Adama, Ethiopia, occur before ART initiation
Introduction: Although antiretroviral therapy (ART) leads to reduced tuberculosis (TB) incidence in people with HIV (PWH), ART recipients remain at higher risk of TB compared to HIV-seronegative people. With accelerated ART rollout in sub-Saharan Africa, increasing proportions of TB cases among PWH in people receiving long-term ART have been reported. Objective: To determine TB notifications among
The Importance of Being Grade 3 : A Plea for a Three-tier Hybrid Classification System for Grade in Primary Non–muscle-invasive Bladder Cancer
Grade is an important determinant of progression in non–muscle-invasive bladder cancer. Although the World Health Organization (WHO) 2004/2016 grading system is recommended, other systems such as WHO1973 and WHO1999 are still widely used. Recently, a hybrid (three-tier) system was proposed, separating WHO2004/2016 high grade (HG) into HG/grade 2 (G2) and HG/G3 while maintaining low grade. We asses
Microhabitat accessibility determines peptide substrate degradation by soil microbial community
Soil pore space, considered the most complex biomaterial that exists, generates a complex environment, that gives rise to a wide variety of properties, such as microbial diversity and carbon storage. Soils contain, at the same time, the largest carbon reservoir on earth and an immense amount of nutrient-limited microbial biomass. The reason why this carbon is not consumed by soil microbes is attri
The number of episodes of major psychiatric and substance use disorders as an index of genetic risk and genetic heterogeneity
We investigate whether number of episodes (NoEs) meaningfully reflect genetic risk and genetic heterogeneity for five primary disorders—Drug Use Disorder (DUD), Alcohol Use Disorder (AUD), Major Depression (MD), Bipolar Disorder (BD), and Schizophrenia (SZ) ascertained from Swedish population registries. We utilize Genetic Risk Ratios (GRR)—defined as the ratio of the genetic risk for secondary di
Mosaic chromosomal alterations in hematopoietic cells and clinical outcomes in patients with multiple myeloma
Mosaic chromosomal alterations (mCAs) in hematopoietic cells increase mortality and risk of hematological cancers and infections. We investigated the landscape of mCAs and their clinical consequences in 976 patients with multiple myeloma undergoing high-dose chemotherapy and autologous stem cell support (ASCT) with median 6.4 years of follow-up. mCAs were detected in the stem cell harvest product
Performance of five cardiotocography classification templates in labor : a cohort study
Objective: New guidelines for the interpretation of cardiotocography (CTG) have been presented by FIGO in 2015 (FIGO-15) and by NICE in 2017 (NICE-17) and 2022 (NICE-22) In Sweden, a previous template from 2009 (SWE-09) was replaced in 2017 (SWE-17). The objective of the study was to compare these five different templates for CTG classification regarding sensitivity, specificity, positive and nega
The future is here : an overview of technology in diabetes
Threshold Saturation for Quantitative Group Testing with Low-Density Parity-Check Codes
We recently proposed a quantitative group testing (GT) scheme with low-complexity peeling decoding based on low-density parity-check (LDPC) codes. Based on finite length simulations and a density evolution analysis we were able to demonstrate that simple (dv,dc)-regular LDPC codes can be more efficient for GT than existing generalized LDPC (GLDPC) code constructions based on BCH component codes. E
Syria’s self-governing democratic north-east comes under attack with country in flux
Review of particle physics
The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 2,717 new measurements from 869 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark ph
The Cretaceous Diatom Database : A tool for investigating early diatom evolution
The Cretaceous period is the time of the first appearance of the diatoms in the fossil record. These fossils give us direct evidence of the age and early evolution of the diatom lineage. The fossil record, however, is incomplete and therefore often extrapolated through time-calibrated phylogenies. These two approaches offer different perspectives on the early evolution of diatoms, which is still p
Differential cross-sections for events with missing transverse momentum and jets measured with the ATLAS detector in 13 TeV proton-proton collisions
Measurements of inclusive, differential cross-sections for the production of events with missing transverse momentum in association with jets in proton-proton collisions at s = 13 TeV are presented. The measurements are made with the ATLAS detector using an integrated luminosity of 140 fb−1 and include measurements of dijet distributions in a region in which vector-boson fusion processes are enhan
The Republic of Turkey and its Unresolved Issues: 100 Years and Beyond
This open access book explores the Republic of Turkey's unresolved issues that have persisted over the past 101 years. It adopts an interdisciplinary perspective to explore the challenges facing the country to critically analyse the broader historical, political, economic, social and psychological dimensions that intersect with these challenges. It offers a rich and nuanced understanding of Turkey
CMES Regional Outlook: The Fall of the Assad Regime: Challenges and Opportunities for Rojava
A longitudinal study of the association between attending cultural events and coronary heart disease
Background: The experiences of art and music are an essential part of human life and this study aimed to examine the longitudinal association between cultural participation and coronary heart disease. Methods: This was a longitudinal study on a randomly selected representative adult cohort (n = 3296) of the Swedish population. The study period was over 36 years (1982–2017) with three separate eigh
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BACKGROUND: Prenatal diagnosis brings together a group of technologies that focus on the detection of congenital defects or anomalies of genetic and multifactorial origin. Irrespective of the type of test, any prenatal diagnostic technology must be accompanied by pre- and post-test counselling. The ethical underpinning of such counselling is of paramount interest to prenatal medicine and has been
Traffic safety implementation at local level in line with 2030 Agenda for Sustainable Development : synergies, challenges and enablers
This study explores how traffic safety implementation at local level in line with the 2030 Agenda for Sustainable Development is characterised. By investigating interactions between traffic safety and other sustainability goals (synergies), as well as identifying contradictions between goals and conflicting interests (challenges), the study aims to pinpoint the main enablers for implementing traff