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How can live-performed chamber operas be conceptualized as immersive games with interactive features? This artistic study has resulted in a system model through which degrees of immersion may be generated and analyzed from physical, social, and psychical stimuli. A differentiation of immersive modes has been made possible by the framing of opera-making as game design. The findings indicate that so
How can microsocial rituals connected to a specific site be used as interaction templates for artistic purposes? And how can we distort such rituals artistically in order to make them memorable events? As artists, we regard distortion as the process that gives character and distinction to things and situations, as well as something that confuses and enriches information and interpretation. Through
Introduction: Chronic pain negatively impacts a range of sensory and affective behaviors. Previous studies have shown that the presence of chronic pain not only causes hypersensitivity at the site of injury but may also be associated with pain-aversive experiences at anatomically unrelated sites. While animal studies have indicated that the cingulate and prefrontal cortices are involved in this ge
To probe into the artistic possibilities of Artificial Intelligence (AI) generating operatic elements, we have engaged in a practice-led inquiry as designers and artists. We took the process of prototyping a chamber opera with interactive features as our starting point, exploring how AI could work as a source of stimuli in opera productions, and how prototyping might add to the design and evaluati
In this article, we present results from a literature review of intrinsic, instrumental, and relational values of nature conducted for the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services, as part of the Methodological Assessment of the Diverse Values and Valuations of Nature. We identify the most frequently recurring meanings in the heterogeneous use of different v
Context. Stars tend to form in clusters, but many escape their birth clusters very early. Identifying the escaped members of clusters can inform us about the dissolution of star clusters, but also about the stellar dynamics in the galaxy. Methods capable of finding escaped stars from many clusters are required to fully exploit the large amounts of data in the Gaia era. Aims. We present a new metho
Quantum dots are frequently used as charge-sensitive devices in low-temperature experiments to probe electric charge in mesoscopic conductors where the current running through the quantum dot is modulated by the nearby charge environment. Recent experiments have operated these detectors using reflectometry measurements up to gigahertz frequencies rather than probing the low-frequency current throu
Prostate-specific antigen (PSA) was discovered in the 1970s, with assays to detect PSA in blood approved by the US Food and Drug Administration in 1986. Almost from the very beginning, its role as a prostate cancer marker has been severely misunderstood. One of the most well-known misconceptions is that prostate cancer detectable by elevated PSA in asymptomatic men requires treatment, irrespective
Why are Western governments not retrieving detained minor nationals from Al-Hol’s purgatory-like conditions? This article shows, under international human rights law, that the status of detained children as rights bearers is uncontroversial, as is their right to positive protection. We raise issues from recent debate on the securitisation of geopolitics in the relationship between the Middle East
Sheep and their wool were paramount to Viking Age economies. The importance of wool cannot be underestimated, especially as the woollen sail was implemented on ships in general during this period. This paper investigates sheep management and landscape use in Viking Age Löddeköpinge in Scania, southern Sweden, through a multiproxy approach, integrating multi-isotope methods with zooarchaeological a
Vad är det som överlåts vid en transaktion avseende fast egendom? Ofta vållarden frågan inte några svårigheter att besvara och innebörden framgår vanligtvis tydligt av såväl köpeavtal som köpebrev. Men vad gäller i det fall parternainte tillräckligt tydligt har formulerat köpeobjektet i avtalet, om parterna inte äröverens om vad som ingår i överlåtelsen eller om formuleringarna ser olika ut iköpea
WNT/β-catenin signaling is essential for colon cancer development and progression. WNT5A (ligand of non-canonical WNT signaling) and its mimicking peptide Foxy5 impair β-catenin signaling in colon cancer cells via unknown mechanisms. Therefore, we investigated whether and how WNT5A signaling affects two promoters of β-catenin signaling: the LGR5 receptor and its ligand RSPO3, as well as β-catenin
Carrying capacity, a concept entrenched in the natural resources and environmental field for nearly two centuries, has continually evolved to address the conflicts and sustainability of the human- nature relationship. This paper introduces an analytical framework for understanding carrying capacity within the context of the human- nature relationship. It systematically reviews the progression of i
Introduction: The impact of moderate haemophilia on health-related quality of life (HRQoL) and physical activity (PA) is not well known. In previous studies, persons with factor VIII/factor IX activity (FVIII/FIX:C) below 3 IU/dL were associated with a more severe bleeding phenotype than predicted. Aim: To explore HRQoL and PA in patients with moderate haemophilia A (MHA) and B (MHB). Methods: A c
The prototypical chalcogenide perovskite BaZrS3, characterized by its direct band gap, exceptionally strong light-harvesting ability, and good carrier transport properties, provides fundamental prerequisites for a promising photovoltaic material. This inspired the synthesis of BaZrS3 in the form of thin films, using sputtering and rapid thermal processing, aimed at device fabrication for future op
We investigate network nonlocality in the triangle scenario when all three parties have no input and binary outputs. Through an explicit example, we prove that this minimal scenario supports nonlocal correlations compatible with no-signaling and independence of the three sources, but not with realisations based on independent quantum or classical sources. This nonlocality is robust to noise. Moreo
Artificial Kitaev chains, formed by quantum dots coupled via superconductors, have emerged as a promising platform for realizing Majorana bound states. Even a minimal Kitaev chain (a quantum dot-superconductor-quantum dot setup) can host Majorana states at discrete sweet spots. However, unambiguously identifying Majorana sweet spots in such a system is still challenging. In this work, we propose a
Addressing intertwined crises of climate change and biodiversity loss is a pressing global challenge, with trees playing pivotal roles in promoting carbon sequestration and habitat diversity. However, there is a distinct knowledge gap concerning the global drivers shaping tree cover and its heterogeneity, particularly the roles and relative importance of large herbivores and fire compared to clima
Genomic analyses have redefined the molecular subgrouping of pediatric acute lymphoblastic leukemia (ALL). Molecular subgroups guide risk-stratification and targeted therapies, but outcomes of recently identified subtypes are often unclear, owing to limited cases with comprehensive profiling and cross-protocol studies. We developed a machine learning tool (ALLIUM) for the molecular subclassificati
