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Refining the use of blood cultures

This thesis is built upon four research projects, in which we investigated different aspects of increasing the diagnostic yield of blood cultures. Blood culture sampling using a single venipuncture (single-sampling strategy, SSS) is non-inferior to sampling from two separate venipunctures when sensitivity is considered. The effect of SSS on blood culture contamination rate is less known. In Study

Between Meaning and Noise: Exploring Communication Excess in AI-Permeated Communication Environments

Scarcity, abundance, and excess – the experience of having too little, just enough, or too much of something (Abbott, 2014) – we frequently encounter in our lives. However, given recent advancements in generative artificial intelligence (GenAI), we now face an unprecedented volume of communication across digital media contexts (Schulz et al., 2025). GenAI enables faster, more efficient ways of proScarcity, abundance, and excess – the experience of having too little, just enough, or too much of something (Abbott, 2014) – we frequently encounter in our lives. However, given recent advancements in generative artificial intelligence (GenAI), we now face an unprecedented volume of communication across digital media contexts (Schulz et al., 2025). GenAI enables faster, more efficient ways of pro

AI-Mediated Self-Presentation: Towards a New Understanding of Authenticity in AI Society

This paper challenges the dominant conceptualization of authentic self-presentation as real, genuine or true expression of inner essence or social identity (Lehmann et al., 2019) and calls for its redefinition in light of the rise of AI-generated content within algorithmically mediated online environments. Authenticity has long been central to identity construction and self-presentation, traditionThis paper challenges the dominant conceptualization of authentic self-presentation as real, genuine or true expression of inner essence or social identity (Lehmann et al., 2019) and calls for its redefinition in light of the rise of AI-generated content within algorithmically mediated online environments. Authenticity has long been central to identity construction and self-presentation, tradition

Forecasting indoor air temperatures in tropical hospitals to improve patient health and preparedness for extreme heat

Extreme heat is a growing public health threat in tropical Africa, especially in Ghana where outdoor maximum daily temperatures (Tx) regularly exceed 35 °C. Vulnerability to heat is socially and economically differentiated, with pregnant women, young children, elderly people, and people with chronic health conditions most at risk. High proportions of these groups are found in hospitals, yet little

Navigating Health at Sea: Work, Stress, and lifestyle as Drivers of Seafarers' Wellbeing and Self-Rated Health

Background: Seafarers constitute a global workforce exposed to unique psychosocial, organisational, and environmental stressors. Despite growing attention to maritime wellbeing, empirical evidence on how these multi level determinants interact to shape mental and physical health remains limited. This thesis aims to identify key determinants of mental health, wellbeing, happiness, and self rated he

Quasicrystal Approximants

The concept of quasicrystal approximants is best pursued with reference to the quasicrystals themselves. This makes the classification of approximants into classes congruent to those for quasicrystals useful, that is, axial and icosahedral. As noted by several authors, work on approximants has come full circle; the initial interest in approximants grew out of a desire to understand particularly th

A Backyard of Affections : Performance

A Backyard of AffectionsPerformance presented as part of 25% seminar of the artistic research project On Ancestrality and Regeneration: Performing Decolonial JourneysThe performance covers two seminal aspects of my life: stories of acceptance, dealing with the loving relationship I developed with my maternal grandmother Voinha; and stories of intolerance, where I delve into my rigid and loveless u

A mixed-methods approach to researching extreme heat : Insights from urban Ghana

Extreme heat is both a chronic and acute threat to the health and well-being of urban populations. The aim of this paper is to share experiences from using a range of quantitative and qualitative methods to conduct research on extreme indoor heat, plus highlight the benefits of taking this more holistic approach. Research conducted in urban Ghana measured temperatures in homes and workplaces, eval

The hypothalamus as a key mediator of neurodegenerative disorders

Background: There are currently no major disease-modifying treatments for neurodegenerative disorders such as Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). HD is caused by a CAG repeat expansion in the huntingtin gene and is characterised by the accumulation of mutant huntingtin (mHTT) protein. ALS is defined by the degeneration of motor neurons

Clinical Outcomes in Percutaneous Coronary Intervention: Studies on Chronic Coronary Syndrome and Drug-Coated Balloons

Background: Percutaneous coronary intervention (PCI) is frequently used in the treatment of chronic coronary syndrome (CCS), although its impact on long-term prognosis and symptom relief remains debated. Among patients undergoing revascularisation with PCI, data on clinical outcomes following drug-coated balloon (DCB) based PCI in unselected patient populations is limited, and the comparative effe

Infrastructuring cultural policy: the case of Creative Europe’s “Cultural and Creative Spaces and Cities”

Cultural networks play an important role in cultural governance: facilitatingcooperation between local and EU policy actors and shaping policymakingprocesses. The network-led, Creative Europe-financed project Cultural andCreative Spaces and Cities (CCSC; 2018–2021) experimented with policy co-creation between civic, cultural, and administrative stakeholders, addressing avariously discussed gap bet

Dentro do Mar tem Rio (Within the Sea a River) : Sound Installation

During an ethnographic fieldwork trip conducted in June 2025 in Brazil between in two cities 4000 kilometers apart, Rio de Janeiro, my hometown, and Manaus, capital of the state of Amazonas, I conducted interviews with the eldest generation of my aunts and uncles in order to continue the investigation I have been engaged in during my doctoral studies on ancestry, migration and the ever-present eff

‘We All Need to be One and Listen to Each Other’ : Institutional Complexity and the Prospects of Co-management in Ghana’s Artisanal Fisheries

Small-scale artisanal fishery in Ghana has encountered unprecedented challenges in recent decades, including dwindling fish stocks. Correspondingly, the sector’s institutional landscape has evolved to comprise a diverse array of institutions. Drawing on qualitative fieldwork conducted in two fishing communities in Ghana, this paper examines the complex interplay between formal and informal institu

“It is for home but we use it for work” : intra-urban comparison of infrastructure and home-based enterprises in Accra

Urban infrastructure is crucial for livelihoods and economic growth, however, access remains fragmented. Such differential infrastructure provision within cities necessitates intra-urban comparison and a renewed commitment to re-thinking between and within neighborhoods in ways that do not universalize infrastructure geographies. This paper examines how electricity and water infrastructure affect

Status on stroke and stroke care in Europe 2023 : Stroke Service Tracker 2023 data based on 1,460,360 strokes in 47 European nations

INTRODUCTION: Inequity in stroke care in Europe has previously been reported despite the existence of evidence-based cost-effective interventions for both prevention and treatment. This report aims to provide comprehensive data on stroke care in Europe in 2023 and explore associations to European regions, organisational and economic factors. PATIENTS AND METHODS: The Stroke Service Tracker, an ann

Multi-model simulation performance of monthly water balance models for global catchments : Thresholds and structural sensitivity

Water balance models provide insights into ongoing changes in the water cycle. Among them, monthly water balance models (MWBMs) are especially suitable for large-sample and global assessments, which are important for adaptation to global environmental change. This study evaluates monthly water balances from 14 models across more than 2,000 global catchments, comparing the modelś capacities to repr

Auriga Streams III : the mass–metallicity relation does not rule out tidal mass-loss in Local Group satellites

The mass–metallicity relation is a fundamental galaxy scaling law that has been extended to the faintest systems in the Local Group. We show that the small scatter in this relation, which has been used to argue against tidal mass-loss in Local Group satellites, is consistent with the level of disruption in the Auriga simulations. For every accreted system in Auriga, we compute stellar masses and m