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Randomised controlled trial (RCT) protocols contain essential details needed to understand and evaluate the trial's planned aims, design, data collection methods, monitoring, data analysis, and participants' safety. However, key information is often omitted from paediatric RCT protocols, including details on dose adjustments of interventions based on age, body surface area, or weight; developmenta

The saturation of the IJTAG concept and its approval as the IEEE 1687 standard in 2014 has generated a wave of research activities and created demand for a set of appropriate and challenging benchmarks. This paper presents such a set developed by an industrial and academic consortium and constructed in a way that facilitates objective comparison of experimental results across research groups as we

BACKGROUND: TF (transcription factor) Prdm16 (positive regulatory domain-containing protein 16) regulates hematopoietic and neuronal stem cell homeostasis, adipose differentiation, and cardiac development. Its role in the circulatory system extends beyond the heart, as Prdm16 loss in arterial endothelial cells (ECs) impairs arterial reperfusion of ischemic mouse limbs due to endothelial dysfunctio

The clustering of certain proteins into oligomers and fibrils, known as amyloids, underlies the pathology of diseases such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes. These processes are counteracted by the cellular protein quality control system, which includes molecular chaperones that interact with disease-associated proteins. One such chaperone is DNAJB6b, which has gaine

Friendship is a common and complex social bond. Among friendship practices yet to be fully understood are group- versus dyadic-oriented friendship styles, or whether people socialize with one versus multiple friends at a time. We report two studies comparing friendship styles and relational mobility among 1674 young adults (18–35 years old) in Japan and the United Kingdom. Respondents from both co

Occupational exposure to cancer-causing agents is a major, yet preventable, contributor to cancer in Europe and globally. In the European Union (EU), cancer is responsible for nearly half of all work-related deaths, underscoring the critical need for prevention measures. Effective strategies typically involve regulatory and workplace measures aimed at reducing or eliminating exposure risks. Raisin

The European Code Against Cancer (ECAC) provides evidence-based recommendations to help individuals reduce their cancer risk. For the 5th edition (ECAC5), recommendations on ultraviolet radiation (UVR) and indoor radon exposures were updated, and complementary recommendations for policymakers were introduced. UVR and radon are classified as carcinogenic to humans (group 1 carcinogens) in the Inter

Investigates memory initiatives in three of the world’s hardest to solve conflicts and how they can be invested with more constructive dynamics Agonistic memory work as a framework for conflict transformation In-depth case studies from Colombia, Israel-Palestine, and Northern Ireland Careful historical tracing of memory politics in zones of protracted conflict Agonistic memory dialogues a

CT-based radiostereometric analysis (CT-RSA) is a method of measuring implant micromotion using low-dose CT scans. We evaluated the precision, accuracy, and observer reliability of CT-RSA for measuring femoral stem translation in THA in vitro. A cementless femoral stem was implanted in a synthetic femur mounted on a calibrated micrometer platform. Controlled translations were applied along each or

Most European Union (EU) residents live in areas where outdoor air pollution levels exceed the 2021 World Health Organization (WHO) air quality guidelines for fine particles and nitrogen dioxide. Outdoor air pollution is classified as carcinogenic to humans, and both outdoor and indoor air contain established human carcinogens, including diesel exhaust particulates, benzo(a)pyrene [B(A)P] and benz

A resolved optical image of a gamma-ray emitter would be of enormous scientific interest. For gamma-ray sources associated with interacting stars (colliding winds or novae), stellar intensity interferometry (SII), envisioned as a second observing mode at the Cherenkov Telescope Array Observatory (CTAO), could yield images of the systems in visible light. Recent radius measurements of massive stars

This is the Replicated Computational Results (RCR) Report for the article “Testing Abstractions for Cyber-Physical Control Systems.” The article empirically studies how substituting different components in Cyber-Physical Systems (CPSs) testing with simulators impacts the fault-exposition. This RCR report describes the artefacts used in the article, how to use the testing setups used in the article

BACKGROUND: Previous research has identified a need for relevant evidence-based clinical guidelines in primary care physiotherapy. However, an essential first step is to identify the most prevalent diagnoses among patients seeking physiotherapy. Thus, this study aims to (I) identify the most prevalent musculoskeletal diagnoses and, (II) describe physiotherapy utilization and patient characteristic

The evolutionary transition to eusociality in the solitary ancestors of social insects, like ants, termites, wasps and bees, may have been initiated by an environmental induction of group living. Plasticity in social behaviour in response to the environment can be found in facultatively social insects. However, it is currently unknown which environmental cues trigger the individual decision of an