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Viruses in the genome are important for our brain

By Paulina [dot] Pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 28 February 2018 New publication! Please click here to read about our latest publication TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells.Also, please click here to go to a short presentation of this research in Science: Science

https://www.molecular-neurogenetics.lu.se/article/viruses-genome-are-important-our-brain - 2025-05-07

Per Ludvik's thesis is officially nailed!

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 9 April 2019 2019-04-09. Today we celebrated the official nailing of Per Ludvik Brattås' thesis entiteled "The Epigenetic Impact of Transposable Elements in Human Brain Development". Per's defence will take place on April 26th at 13 o'clock at the Segerfalk lecture hall (BMC, A10) - you are most welcom to join

https://www.molecular-neurogenetics.lu.se/article/ludviks-thesis-officially-nailed - 2025-05-07

New publication in Nature Communications!

Published 24 July 2019 We're happy to present our most recent publication "Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors" published on July 18th. Our study sheds light on the darker parts of our genetic heritage. To find out more please click on the below link.Lund University's press release Nature Communications: Activation of neuronal

https://www.molecular-neurogenetics.lu.se/article/new-publication-nature-communications - 2025-05-07

På svenska: Nya gentekniken kräver en bred debatt

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 25 November 2019 Läs den spännande debatten om den nya gentekniken Crispr, skriven av forskare från gruppen Crispr ideas vid Pufendorfinstitutet, Lunds universitet, på SvD Debatt. SvD Debatt: ”Vi måste ta ställning till nya gentekniken” Aftonbladet: "Den nya gensaxen måste diskuteras"   Om debattörerna: Karin B

https://www.molecular-neurogenetics.lu.se/article/pa-svenska-nya-gentekniken-kraver-en-bred-debatt - 2025-05-07

Nailing completed!

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 3 April 2020 Today we celebrated official nailing of Daniela Grassi's thesis "Development and Applications of in vitro Models to Study Human Brain Evolution and Disease". The defence will take place on Thursday April 23rd at 9.00 o'clock and it will be made availably digitally for you to join!

https://www.molecular-neurogenetics.lu.se/article/nailing-completed - 2025-05-07

Thesis Defence Interview – Daniela Grassi

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 20 April 2020 Daniela Grassi will be defending her thesis on Thursday 23rd of April 2020. Here, Daniela tells us about her research in the Molecular Neurogenetics group. Please click here for full article: https://www.stemcellcenter.lu.se/article/thesis-defence-interview-daniela-grassi 

https://www.molecular-neurogenetics.lu.se/article/thesis-defence-interview-daniela-grassi - 2025-05-07

New article on autophagy and the treatment of Huntington disease!

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 18 May 2020 Interested in autophagy or Huntington disease? Please click here to go to our newest publication Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease and to more information on our work in the field.

https://www.molecular-neurogenetics.lu.se/article/new-article-autophagy-and-treatment-huntington-disease - 2025-05-07

Meet Christopher Douse

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 15 October 2020 Read here about Christopher Douse who joined our group at the beginning of 2020 and works on developing a research programme on newly-discovered guardians of the human genome. For article please click on the following link: https://www.stemcellcenter.lu.se

https://www.molecular-neurogenetics.lu.se/article/meet-christopher-douse - 2025-05-07

Lund CRISPR facility is here to help!

Published 19 November 2020 Read about how the CRISPR facility at Lund Stem Cell Center can help you with your experiments CRISPR is a simple yet powerful Nobel Prize winning technology that allows sequence specific editing and manipulation of DNA sequences. The CRISPR facility at Lund Stem Cell Center is here to help you with your projects using this technology. To read more please go to: https://

https://www.molecular-neurogenetics.lu.se/article/lund-crispr-facility-here-help - 2025-05-07

Activation of ancient viruses during brain development causes inflammation

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 19 March 2021 Researchers from Lund Stem Cell Center highlight the importance of controlling viral elements that reside in the genome and how their activation during development may contribute to brain disorders later in life. To read the article, please go to: https://www.stemcellcenter.lu.se/article/activatio

https://www.molecular-neurogenetics.lu.se/article/activation-ancient-viruses-during-brain-development-causes-inflammation - 2025-05-07

Vetenskap & Hälsa: Aktivering av gamla virus orsakar inflammation senare i livet

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 19 March 2021 Är du intresserad i vår forskning? Läs om vår studie som visar att dysreglering av endogena retrovirus under hjärnans utveckling kan leda till både inflammation i hjärnan och genuttrycksmönster som är förbundna med olika neurologiska sjukdomar senare i livet. För att läsa hela artikeln, klicka här

https://www.molecular-neurogenetics.lu.se/article/vetenskap-halsa-aktivering-av-gamla-virus-orsakar-inflammation-senare-i-livet - 2025-05-07

Stem Cell Podcast - featuring Johan Jakobsson!

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 5 May 2021 Click the link below to listen to the latest Stem Cell Podcast - featuring Johan Jakobsson Ep. 192: “Gene Expression and the Brain” Featuring Dr. Johan Jakobsson:  https://stemcellpodcast.com/ep-192-gene-expression-and-the-brain-featuring-dr-johan-jakobsson    

https://www.molecular-neurogenetics.lu.se/article/stem-cell-podcast-featuring-johan-jakobsson - 2025-05-07

What makes us human? The answer may be found in overlooked DNA.

Published 14 October 2021 Read about our research on a previously overlooked part of our DNA, so-called non-coded DNA. Our DNA is very similar to that of the chimpanzee, which in evolutionary terms is our closest living relative. Stem cell researchers at Lund University in Sweden have now found a previously overlooked part of our DNA, so-called non-coded DNA, that appears to contribute to a differ

https://www.molecular-neurogenetics.lu.se/article/what-makes-us-human-answer-may-be-found-overlooked-dna - 2025-05-07

Outforskat DNA förklarar skillnaden mellan människa och schimpans

By paulina [dot] pettersson [at] med [dot] lu [dot] se (Paulina Pettersson) - published 14 October 2021 Läs här om vår forskning om en tidigare förbisedd del i vårt DNA, så kallat icke-kodat DNA. Vårt DNA är mycket likt schimpansens, som evolutionärt är vår närmaste levande släkting. Nu har stamcellsforskare i Lund hittat en tidigare förbisedd del i vårt DNA, så kallat icke-kodat DNA, som tycks bi

https://www.molecular-neurogenetics.lu.se/article/outforskat-dna-forklarar-skillnaden-mellan-manniska-och-schimpans - 2025-05-07

IPCC Synthesis Report provides common conclusion about the state of knowledge on climate change

Published 5 November 2014 During the past week, 350 delegates from 120 countries have gathered in Copenhagen, to go through and come to a common conclusion about the state of knowledge on climate change. The result was finalized as a synthesis report which states that the human influence on the climate system is clear and recent anthropogenic emissions of greenhouse gases are the highest in histor

https://www.merge.lu.se/article/ipcc-synthesis-report-provides-common-conclusion-about-state-knowledge-climate-change - 2025-05-07

New guest researcher: Franziska Aemisegger

Published 1 December 2014 We would like to welcome Franziska Aemisegger, who will be a MERGE guest researcher for the coming two years. For the coming two years, Franziska Aemisegger will be a MERGE guest researcher with a Swiss National Science Foundation Fellowship (SNSF). In her current research she is studying land-atmosphere interactions in the midlatitude water cycle from a weather systems p

https://www.merge.lu.se/article/new-guest-researcher-franziska-aemisegger - 2025-05-07

Advanced climate models lacks computing power

Published 27 November 2014 Comparing the first simple climate models with those of today is like comparing a little blurry black and white line drawing with a large, high-resolution full-color photo. Everything has increased dramatically - both complexity, geographical resolution and model datasets. Read the interview with Markku Rummukainen, coordinator of MERGE. - The development is quickly movi

https://www.merge.lu.se/article/advanced-climate-models-lacks-computing-power - 2025-05-07