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The benefits and side effects of common pain meds for osteoarthritis of the knee and hip

In a new meta-analysis (a compilation of results from a number of different research studies), the benefits and side effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), paracetamol, and opioids have been studied. The research study included data from 181 publications describing 192 clinical trials involving a total of over 100,000 patients. The researchers found that the NSAID etoricoxib (6

https://www.arthritisportal.lu.se/article/benefits-and-side-effects-common-pain-meds-osteoarthritis-knee-and-hip - 2025-09-11

How common is knee osteoarthritis?

A Chinese research group has compiled data from 88 different scientific studies on the prevalence of knee osteoarthritis. The studies were from all around the world and together included more than 10 million people. The researchers estimated that for individuals aged 40 years and older, the global prevalence of knee osteoarthritis is around 23%. This means that almost every fourth person over the

https://www.arthritisportal.lu.se/article/how-common-knee-osteoarthritis - 2025-09-11

PRP injections no more effective than placebo

PRP treatment (platelet-rich plasma) is a relatively new experimental treatment that is often marketed to be effective for patients with osteoarthritis. However, there is a lack of high-quality research claiming the effectiveness of the treatment. Researchers from Brazil have recently published results from a small clinical trial (including 61 patients) evaluating three different treatments. The p

https://www.arthritisportal.lu.se/article/prp-injections-no-more-effective-placebo - 2025-09-11

Osteoarthritis roundtable: Best from the ACR conference 2021

Doctors Jack Cush, Martin Englund, Gillian Hawker, Tihuna Neogi, and Kent Kwoh discuss the best OA research from the 2021 ACR (American College of Rheumatology) conference, including a new study indicating that the diabetes medicine metformin lowers the risk of developing osteoarthritis. Dr. Jack Cush is a professor of internal medicine at The University of Texas Southwestern Medical School, in th

https://www.arthritisportal.lu.se/article/osteoarthritis-roundtable-best-acr-conference-2021 - 2025-09-11

Increased burden by osteoarthritis in the world

In a recent study, a group of scientists have evaluated the burden of osteoarthritis over the past three decades, using data from the worldwide initiative ”Global Burden of Disease study 2019.  The results show that the number of people affected by osteoarthritis has increased by about 113 percent in 30 years, from about 248 million in year 1990 to about 530 million in year 2019. The authors concl

https://www.arthritisportal.lu.se/article/increased-burden-osteoarthritis-world - 2025-09-11

Is there a link between OA and obesity?

Researchers from Australia have investigated the incidence of obesity in patients with OA undergoing knee replacement. In a recent study from Australia researchers have investigated the incidence of obesity in patients undergoing knee replacements because of their OA. The results were compared to the incidence of obesity in the general population. The results show that of the 56 000 patients who u

https://www.arthritisportal.lu.se/article/there-link-between-oa-and-obesity - 2025-09-11

Frequent use of strong painkillers in patients with knee osteoarthritis the years before total knee replacement

Researchers have investigated the use of strong painkillers the years prior total knee replacement. A recent study from England and Sweden (Lund University) has investigated the number of patients with knee osteoarthritis having required treatment with opioids in the years prior to total knee replacement. Opioids are a group of strong painkillers including Morphine, Oxycodone, Tramadol and Citodon

https://www.arthritisportal.lu.se/article/frequent-use-strong-painkillers-patients-knee-osteoarthritis-years-total-knee-replacement - 2025-09-11

Doctoral thesis: Imaging techniques for studies of knee osteoarthritis

Example MRI images and corresponding map from the relaxation parameter T2* of meniscus samples from knees with (right) and without (left) known knee osteoarthritis. Picture: Emma Einarsson The aim of this thesis was to investigate imaging techniques to study tissues and degenerative changes related to knee osteoarthritis. Osteoarthritis is commonly affecting the knee joint. At a late stage of the

https://www.arthritisportal.lu.se/article/doctoral-thesis-imaging-techniques-studies-knee-osteoarthritis - 2025-09-11

Does my diet affect my OA?

We interviewed a dietician to find out more about if and how your diet might affect your OA. Whether a certain diet can make a difference or even make It better when it comes to osteoarthritis (OA) is a question that has been asked several times. We spoke to a dietician called Erik Jönsson who works at several health centers in region Skåne. He has met patients with OA many times, even if that’s o

https://www.arthritisportal.lu.se/article/does-my-diet-affect-my-oa - 2025-09-11

TENS or weak opioids, what's best if you suffer from painful knee OA?

In a recent study, researchers investigated two different ways of treating pain in patients with knee osteoarthritis. The one half got to try W-TENS and the other half received weak opioids. They studied both the efficacy and safety in both methods. Patients with nociceptive pain from their knee OA often receive weak opioids, even though it is well known that the efficacy is moderate. It is also k

https://www.arthritisportal.lu.se/article/tens-or-weak-opioids-whats-best-if-you-suffer-painful-knee-oa - 2025-09-11

Will it be possible to predict the future health status of your knee tissues?

Gustavo is a mechanical engineer from Colombia. During his master's studies, Gustavo got the opportunity to conduct an internship in Lausanne, Switzerland. In Lausanne, he worked in orthopedics and studied the mechanical response of knee implants for total knee replacements using numerical modeling. When Gustavo came home from Lausanne, he was offered a PhD position at the University of Eastern Fi

https://www.arthritisportal.lu.se/article/will-it-be-possible-predict-future-health-status-your-knee-tissues - 2025-09-11

Cannabidiol (CBD) to relieve OA pain. Does it work?

A recent study from Denmark investigated which effect CBD has in hand osteoarthritis and psoriatic arthritis. For 12 weeks, one half received synthetic CBD and the other half received placebo, as an add-on to their usual analgesics. The researchers investigated more than pain relief, including sleep quality and mental health. The participants who got CBD had 20-30 mg CBD every day for 12 weeks. Th

https://www.arthritisportal.lu.se/article/cannabidiol-cbd-relieve-oa-pain-does-it-work - 2025-09-11

Auricular acupressure to relieve OA pain?

Researchers studied if auricular acupressure could work as pain relief in osteoarthritis patients at 65 years old or older. In the study, researchers also investigated the participants' sleep quality. All the participants were 65 years old or more and lived in nursing homes in Korea.  There is a link between osteoarthritis pain and poor sleep. According to the study, sleep quality in people withou

https://www.arthritisportal.lu.se/article/auricular-acupressure-relieve-oa-pain - 2025-09-11

Exercise led by a trainer instead of opioids?

It has been known for many years that movement and exercise in different forms are beneficial and can decrease pain for those with osteoarthritis. One might have to look around to find a form of exercise that fits since it is individually. Some prefer to train on their own, and others prefer training in a group. Some get offered to participate in classes led by a trainer/physiotherapist from their

https://www.arthritisportal.lu.se/article/exercise-led-trainer-instead-opioids - 2025-09-11

Osteoarthritis and stroke, is there a link?

The Arthritis portal earlier wrote about if there is a link between osteoarthritis and other diseases, for example, cancer. In a new study, researchers investigated if there is a link between hip osteoarthritis and stroke. A stroke is a bleeding or blood clot in the brain. A stroke can cause more or less permanent damage, depending on how damaged the brain gets. There are several risk factors for

https://www.arthritisportal.lu.se/article/osteoarthritis-and-stroke-there-link - 2025-09-11

New study finds ruptured ACLs can heal without surgery

A recent study published in the British Journal of Sports Medicine, challenged the common assumption that an ACL injury cannot heal. The anterior cruciate ligament (ACL), is the main stabilising ligament in the knee. Rupture of the ACL is most common in young, active individuals, and can have devastating impacts. The most common treatment is ACL reconstruction, which is based on the assumption tha

https://www.arthritisportal.lu.se/article/new-study-finds-ruptured-acls-can-heal-without-surgery - 2025-09-11

Reportage: Get to know the Ph.D. student who wants to contribute to OA on a molecular level

We are following Amanda Sjögren during her Ph.D. to learn more about what she does at work and to find out the aim of her research. Researchers often start their careers with a Ph.D. Earlier this year, Amanda Sjögren began her Ph.D. in Lund at the clinical epidemiology unit, orthopedics, Lund University. During her Ph.D., we will get the opportunity to get an insight into her work and what she's a

https://www.arthritisportal.lu.se/article/reportage-get-know-phd-student-who-wants-contribute-oa-molecular-level - 2025-09-11

Popular lecture by Andrea Dell'Isola

In the picture, you see Andrea Dell'Isola during a lecture that he was invited to give a few weeks ago. Andrea Dell'Isola, research associate and postdoc at the unit for clinical epidemiology, orthopedics, at Lund University. Andrea is also a physiotherapist and has worked clinically before starting full-time research. The lecture interested many, over 300 people sat in the audience to learn more

https://www.arthritisportal.lu.se/article/popular-lecture-andrea-dellisola - 2025-09-11

Genetics can explain why many suffer from hand osteoarthritis

In a new study, 60,000 Swedish twins were studied. Researchers investigated which role genetic factors play in the development of hand osteoarthritis. The genetic factor seems to be a strong contributor to being diagnosed with hand osteoarthritis when visiting specialist care. In this study, the researchers compared the incidence of hand osteoarthritis diagnosed in specialist care, many times by a

https://www.arthritisportal.lu.se/article/genetics-can-explain-why-many-suffer-hand-osteoarthritis - 2025-09-11

Reportage: Meet Fatima, -waiting for surgery

In this series of reports, you will learn about the process for surgical treatment of advanced osteoarthritis, starting from when a patient first sees an orthopedic specialist to ultimately receiving surgery. We will give you insight into the multiple healthcare visits one needs in order to undergo joint replacement. If you or someone you know is waiting to see an orthopedic doctor for assessment

https://www.arthritisportal.lu.se/article/reportage-meet-fatima-waiting-surgery - 2025-09-11