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Epidemiology, bacteriology, and clinical characteristics of HACEK bacteremia and endocarditis: a population-based retrospective study

The objective was to describe the epidemiology, bacteriology, clinical presentation, risk factors for endocarditis (IE), diagnostic workup, and outcome of patients with bacteremia caused by the non-influenzae Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, and Kingella genera (HACEK). A retrospective population-based cohort of patients with bacteremia collected from 2012 to 2017 was iden

https://www.lupop.lu.se/article/epidemiology-bacteriology-and-clinical-characteristics-hacek-bacteremia-and-endocarditis-population - 2025-08-29

SES inequalities in cause-specific adult mortality: a study of the long-term trends using longitudinal individual data for Sweden (1813–2014)

Higher socioeconomic status (SES) is associated with lower mortality, and this correlation has been confirmed using different indicators across several geographical settings. Nevertheless, the timing of the emergence of the SES gradient remains unclear. We used individual-level longitudinal data for a regional population in southern Sweden covering the period between 1813 and 2014, and we applied

https://www.lupop.lu.se/article/ses-inequalities-cause-specific-adult-mortality-study-long-term-trends-using-longitudinal-individual - 2025-08-29

Successful research funded by the European Research Council

Six researchers from Lund University Diabetes Centre have recieved prestigous grants from the European Research Council (ERC). In order to celebrate the success we invited the public to an open seminar. Some of the talks can be reviewed here (in Swedish). Forskning för bättre folkhälsa:Framsteg inom typ 2-diabetes, fetma och hjärtsjukdomar   Föredrag av professor Olle Melander Professor Olle Melan

https://www.ludc.lu.se/article/successful-research-funded-european-research-council - 2025-08-29

From injections to pills - the research on neonatal diabetes

They govern everything we think and do, they give us the ability to feel pain and to secrete insulin: they are the ion channels that are present in every one of our cells and that control the electrical impulses in our nerve and muscle cells. “For me, they are the very spark of life”, says Dame Frances Ashcroft, professor at the University of Oxford, who is also now to be an honorary doctor at Lun

https://www.ludc.lu.se/article/injections-pills-research-neonatal-diabetes - 2025-08-29

200.000 euro to diabetes research

Four researchers have been awarded grants from The Bo and Kerstin Hjelt Diabetes Foundation. The grant consists of Euro 50 000 each and are aiming towards better treatments and prevention of type 2-diabetes. Improved life expectancy and quality of people with diabetesDiabetes affects millions of patients around the world. The two main types of the disease, type 1 and type 2, are both characterized

https://www.ludc.lu.se/article/200000-euro-diabetes-research - 2025-08-29

The role of vitamin A in diabetes

There has been no known link between diabetes and vitamin A -- until now. A new study suggests that the vitamin improves the insulin producing β-cell´s function.The researchers initially discovered that insulin-producing beta-cells contain a large quantity of a cell surface receptor for vitamin A. "There are no unnecessary surface receptors in human cells. They all serve a purpose but which, in ma

https://www.ludc.lu.se/article/role-vitamin-diabetes - 2025-08-29

New research describes the differences between mice and humans

Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs which have worked in animal experiments are not equally successful in humans. The researchers discovered differences – but also unknown similarities – in the function of insulin-producing beta cells. The team have mapped a category of receptors, known as G protein-coupled receptors, which con

https://www.ludc.lu.se/article/new-research-describes-differences-between-mice-and-humans - 2025-08-29

LUDC-IRC ready for take off

Taking advantage of a novel sub-classification of diabetes LUDC-IRC, a newly launched collaboration between academia, the health care system and industry, aims at delivering precision medicine in diabetes. LUDC-IRC consolidation meeting  - We have set the bar high. We very specifically aim at making a difference for diabetes patients by the end of this eight year program. We need to find smart way

https://www.ludc.lu.se/article/ludc-irc-ready-take - 2025-08-29

Newborn babies to be screened for studies on type 1 diabetes and celiac disease (gluten intolerance)

Can insulin taken as an infant in small doses together with food render the immune system used to insulin and thus prevent type 1 diabetes? Can a gluten-free diet and probiotics prevent celiac disease (so called gluten intolerance)? These questions will be asked by two separate studies that are being planned at Lund University in Sweden. A new comprehensive screening of newborn babies in southern

https://www.ludc.lu.se/article/newborn-babies-be-screened-studies-type-1-diabetes-and-celiac-disease-gluten-intolerance - 2025-08-29

New drink keeps blood sugar in check

Food researchers at Lund University in Sweden have discovered that consuming small amounts of chromium mixed with certain amino acids before eating is healthy. Why? Well, this mixture diluted in water suppresses the blood sugar spike that occurs when we eat. Now, they are hoping that the drink – which tastes like ordinary mineral water – will be able to compete with soft drinks and flavoured water

https://www.ludc.lu.se/article/new-drink-keeps-blood-sugar-check - 2025-08-29

The risk of type 1 diabetes not increased by swine flu vaccine Pandemrix

There has been a fear that the swine flu vaccine, Pandemrix, would increase the risk of autoimmune diseases other than narcolepsy. However, a new study of children from Sweden and Finland shows that the vaccine increased neither the risk of developing autoantibodies against insulin-producing beta cells nor the occurrence of type 1 diabetes. Helena Elding Larsson “On the contrary, the risk was redu

https://www.ludc.lu.se/article/risk-type-1-diabetes-not-increased-swine-flu-vaccine-pandemrix - 2025-08-29

“Death receptors” – new markers for type 2 diabetes and cardiovascular disease

Researchers at Lund University in Sweden have found that the presence of death receptors in the blood can be used to directly measure the risk of developing cardiovascular diseases and type 2 diabetes. “We see that people with known risk factors such as high blood sugar and high blood fats also have heightened death receptor levels”, says Professor Jan Nilsson who led the study. Death receptors ar

https://www.ludc.lu.se/article/death-receptors-new-markers-type-2-diabetes-and-cardiovascular-disease - 2025-08-29

Nordic conference in Malmö about Precision Medicine in the future

December 4-5, nordic researchers gathered in Malmö to discuss future challenges in precision medicine, a research field where diagnosis and treatment are based on the individual´s genetic and biological conditions. Focus is on our common and increasing diseases diabetes, cardiovascular disease, cancer and psychiatric diagnosis. "The goal of the meeting is to bring together mordic stakeholders in p

https://www.ludc.lu.se/article/nordic-conference-malmo-about-precision-medicine-future - 2025-08-29

Paradigm shift in the diagnosis of diabetes

A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. We are now seeing the first results of ANDIS – a study covering all newly diagnosed diabetics in southern Sweden — published in The Lancet Diabetes & Endocrinology. The major difference from today’s classification is that type 2 diabetes actually consists of several

https://www.ludc.lu.se/article/paradigm-shift-diagnosis-diabetes - 2025-08-29

Opposites Attract: Assortative Mating and Immigrant–Native Intermarriage in Contemporary Sweden

This paper studies how immigrant–native intermarriages in Sweden are associated with individual characteristics of native men and women and patterns of assortative mating. Patterns of educational- and age-assortative mating that are similar to those found in native–native marriages may reflect openness to immigrant groups, whereas assortative mating patterns that indicate status considerations sug

https://www.lupop.lu.se/article/opposites-attract-assortative-mating-and-immigrant-native-intermarriage-contemporary-sweden - 2025-08-29

Psoriasis is Associated with a High Comedication Burden: A Population Based Register Study

A large body of evidence supports the association between psoriasis and concomitant diseases. However, the study of comedication for these diseases in patients with psoriasis is limited. The current study aimed to investigate the prescription and drug dispensation for comorbidity associated with psoriasis. Read more at https://link.springer.com/article/10.1007/s13555-020-00442-3

https://www.lupop.lu.se/article/psoriasis-associated-high-comedication-burden-population-based-register-study - 2025-08-29

The association between sociodemographic characteristics and dementia in patients with atrial fibrillation

We studied AF patients ≥ 45 years in Sweden 1998-2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Register, and the National Patient Register (NPR) for incident dementia. Cox regression with hazard ratios (HR) and 95% confidence intervals (CI) was used for the association between exposure and outcome, adjusting for age and comorbiditi

https://www.lupop.lu.se/article/association-between-sociodemographic-characteristics-and-dementia-patients-atrial-fibrillation - 2025-08-29

Mammographic density changes during neoadjuvant breast cancer treatment: NeoDense, a prospective study in Sweden

We prospectively included 200 breast cancer patients assigned to neoadjuvant chemotherapy (NACT) in the NeoDense study (2014–2019). Raw data mammograms were used to assess MD with a fully automated volumetric method and radiologists categorized MD using the Breast Imaging-Reporting and Data System (BI-RADS), 5th Edition. Logistic regression was used to calculate odds ratios (OR) for pCR comparing

https://www.lupop.lu.se/article/mammographic-density-changes-during-neoadjuvant-breast-cancer-treatment-neodense-prospective-study - 2025-08-29

Risk of Recurrent Disease 6 Years After Open or Robotic-assisted Radical Prostatectomy in the Prospective Controlled Trial LAPPRO

Conclusive evidence of superiority in oncological outcome for robot-assisted laparoscopic prostatectomy (RALP) over retropubic radical prostatectomy (RRP) is lacking. Read more at https://www.sciencedirect.com/science/article/pii/S2666168320351235

https://www.lupop.lu.se/article/risk-recurrent-disease-6-years-after-open-or-robotic-assisted-radical-prostatectomy-prospective - 2025-08-29