By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 30 May 2021 We propose combining population-based register data with a nested clinical cohort to correct misclassification and unmeasured confounding through probabilistic quantification of bias. We have illustrated this approach by estimating the association between knee osteoarthritis and mortality. Read the paper at https:/

https://www.lupop.lu.se/article/probabilistic-quantification-bias-combine-strengths-population-based-register-data-and-clinical-1 - 2025-07-15

Published 3 May 2018 A platform for safe handling of data at the medical faculty Infosäk will shortly publish complete information about the project. Meanwhile, you can read more here.

https://www.lupop.lu.se/article/infosak - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 31 May 2021 Photo: flickr / Mitchell Joyce Laboratory-based animal research has revealed a number of exposures with multigenerational effects—ones that affect the children and grandchildren of those directly exposed. An important task for epidemiology is to investigate these relationships in human populations. Read the paper a

https://www.lupop.lu.se/article/methodological-issues-population-based-studies-multigenerational-associations - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 1 June 2021 Photo: Pixabay / Gerd Altmann In observational studies using routinely collected data, a variable with a high level of missingness or misclassification may determine whether an observation is included in the analysis. In settings where inclusion criteria are assessed after imputation, the popular multiple-imputatio

https://www.lupop.lu.se/article/multiple-imputation-variance-estimation-studies-missing-or-misclassified-inclusion-criteria - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 2 June 2021 Photo: Pixabay / Gerd Altmann A growing number of studies use data before and after treatment initiation in groups exposed to different treatment strategies to estimate “causal effects” using a ratio measure called the prior event rate ratio (PERR). Here, we offer a causal interpretation for PERR and its additive s

https://www.lupop.lu.se/article/causal-interpretation-rate-change-methods-prior-event-rate-ratio-and-rate-difference - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 2 June 2021 Image from pixabay / pearson0612 The coronavirus disease 2019 (COVID-19) pandemic and the coming transition to a postpandemic world where COVID-19 will likely remain as an endemic disease present a host of challenges and opportunities in epidemiologic research. Read the paper at https://academic.oup.com/aje/article

https://www.lupop.lu.se/article/what-now-epidemiology-wake-pandemic - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 3 June 2021 Suppose that an investigator wants to estimate an association between a continuous exposure variable and an outcome, adjusting for a set of confounders. If the exposure variable suffers classical measurement error, in which the measured exposures are distributed with independent error around the true exposure, then

https://www.lupop.lu.se/article/reducing-bias-due-exposure-measurement-error-using-disease-risk-scores - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 4 June 2021 Photo: Kennet Ruona In aspiring to be discerning epidemiologists, we must learn to think critically about the fundamental concepts in our field and be able to understand and apply many of the novel methods being developed today. We must also find effective ways to teach both basic and advanced topics in epidemiolog

https://www.lupop.lu.se/article/simulation-tool-teaching-and-learning-epidemiologic-methods - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 5 June 2021 Photo: Pixabay / Arek Socha Factorial Mendelian randomization is the use of genetic variants to answer questions about interactions. Although the approach has been used in applied investigations, little methodological advice is available on how to design or perform a factorial Mendelian randomization analysis. Read

https://www.lupop.lu.se/article/factorial-mendelian-randomization-using-genetic-variants-assess-interactions - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 6 June 2021 Unmeasured confounding can bias the relationship between exposure and outcome. Sensitivity analyses generate bias-adjusted measures but these are not much used; this may change with the availability of the E-value (for evidence for causality in observational studies), appealing for its ease of calculation. Read the

https://www.lupop.lu.se/article/bias-factor-maximum-bias-and-e-value-insight-and-extended-applications - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 7 June 2021 Photo: Pixabay / Colin Behrens We illustrate the method and some potential choices using data from England for men diagnosed with melanoma. Various marginal measures are presented and compared. Read the paper at https://academic.oup.com/ije/article/49/5/1614/5896134

https://www.lupop.lu.se/article/reference-adjusted-and-standardized-all-cause-and-crude-probabilities-alternative-net-survival - 2025-07-15

Published 27 May 2021 Fotograf: Håkan Röjder The PhD position is linked to the research project The long reach of the neighborhood: Health, education and earnings in Landskrona, Sweden, 1904-2015, funded by Handelsbankens forskningsstiftelser. The PhD student will work in this project in collaboration with other project members and will be affiliated with the Centre for Economic Demography at LUSE

https://www.lupop.lu.se/article/phd-position-economic-history-neighborhood-effects-over-life-course - 2025-07-15

Published 8 May 2018 Find out how GDPR will affect you and your research! More information, including programme, here.

https://www.lupop.lu.se/article/gdpr-event - 2025-07-15

By anna [dot] axmon [at] med [dot] lu [dot] se (Anna Axmon) - published 16 June 2021 Photo: Pixabay / Gerd Altmann This paper describes the multiform, wave-missing and two-method designs, including their benefits, their impact on bias and power, and other factors that must be taken into consideration when implementing them in an epidemiological study design. Read the paper at https://academic.oup.

https://www.lupop.lu.se/article/reflection-modern-methods-planned-missing-data-designs-epidemiological-research - 2025-07-15

By alexis [dot] bento_luis [at] med [dot] lu [dot] se (Alexis Luis) - published 15 August 2023 An image of co-cultures with neuronal projections in purple and astrocytes in green. Image credit: Isaac Canals. One of Multipark's associated research groups has published a new study that reveals the role of astrocytes in the development of frontotemporal dementia (FTD). Their findings, now in the jour

https://www.multipark.lu.se/article/new-study-reveals-astrocytes-role-frontotemporal-dementia - 2025-07-15

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 11 July 2023 Angela Cenci Nilsson was one of the panellists in a session discussing disease mechanisms, non-dopaminergic cells involved in PD, and the latest development regarding gene and cell therapy approaches. Summer is the right period for recharging our batteries through vacations and travels. It also seems t

https://www.multipark.lu.se/article/summer-greetings-multipark-world-parkinson-congress - 2025-07-15

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 24 August 2023 Illustration of a Lewy body.(Image: istock.com/Marcin Klapczynski) Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test. The s

https://www.multipark.lu.se/article/lewy-body-disease-can-be-detected-symptoms - 2025-07-15

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 4 September 2023 Find out how electrotherapy works without surgery in this video by Roger Olsson. Researchers at Lund and Gothenburg Universities have successfully developed temporary, organic electrodes that can be seamlessly integrated into biological systems. The method, now published in Nature Communications, opens

https://www.multipark.lu.se/article/electrotherapy-without-surgery - 2025-07-15

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 19 September 2023 Brainwaves, or neural oscillations, are periodic electrical activities that occur when large groups of neurons work together. Researchers now hope that these signals will teach us more about hallucinations and psychoses. Photo: Pär Halje Researchers at Lund University have developed a technique for simultaneo

https://www.multipark.lu.se/article/how-psychedelic-drugs-affect-rats-brain - 2025-07-15

By agata [dot] garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 8 February 2022 Toxin-antitoxin pairs consist of a gene encoding a toxin that inhibits bacterial growth and an adjacent gene encoding an antitoxin that counteracts the toxic effect. It is like keeping a bottle of poison on a shelf next to a bottle of the antidote. Researchers in Lund have discovered an antitoxin me

https://www.medicine.lu.se/article/new-multipurpose-switch-inhibiting-bacterial-growth - 2025-07-15