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Grundsjukdomen dödar transplanterade insulinceller

En undersökning där tre typ 1 diabetiker, som fått både njure och bukspottkörtel transplanterade, deltog visar att det är den ursprungliga autoimmuna processen som förstör de nya insulincellerna. Bukspottkörtelns andra funktioner och njuren går fria från angreppet. Två av patienterna fick antikroppar i blodet lång tid innan blodsockerkontrollen började svikta. Den tredje patienten hade antikroppar

https://www.diabetesportalen.lu.se/artikel/grundsjukdomen-dodar-transplanterade-insulinceller - 2025-10-03

Är det välståndet som gör barnen diabetessjuka?

Förespråkarna för hygienhypotesen menar det. Vällevnaden - hög levnadsstandard, välstädade hem utan ohyra, rent vatten och få infektioner - gör att vårt immunförsvar inte utvecklas och då ökar risken att drabbas av autoimmuna sjukdomar, till exempel typ 1 diabetes. Förespråkarna i forskningsprojektet Diabimmune pekar på skillnaden mellan Finland och ryska Karelen. I välståndslandet Finland är före

https://www.diabetesportalen.lu.se/artikel/ar-det-valstandet-som-gor-barnen-diabetessjuka - 2025-10-03

Gammal trotjänare lovande nytt medel vid diabetes

Salasat, ett mer än hundra år gammalt läkemedel mot smärtor i lederna sänker blodsockret och minskar skadliga blodfetter vid typ 2 diabetes. Forskarna finner resultaten så uppmuntrande att de nu går vidare med en längre och större undersökning. Drogen, som ursprungligen kommer från pilträdets bark, har använts inom medicinen i mer än 1 500 år.- Det är en av de äldsta kända drogerna i den västerlän

https://www.diabetesportalen.lu.se/artikel/gammal-trotjanare-lovande-nytt-medel-vid-diabetes - 2025-10-03

När det vattnas i munnen...

Blotta åsynen eller lukten av mat startar en komplex kedja av händelser som bland annat leder till att saliv- och insulinutsöndringen ökar. Nu har forskare upptäckt en genmutation som försämrar kroppens insulinsvar på en frestande och väldoftande måltid. Mekanismen bakom ökad saliv- och insulinutsöndring styrs av det parasympatiska nervsystemet, det vill säga funktioner som regleras av nerver men

https://www.diabetesportalen.lu.se/artikel/nar-det-vattnas-i-munnen - 2025-10-03

Smör ger lägre blodfetter än olivolja

Höga blodfetter ökar i regel kolesterolvärdena i blodet vilket i sin tur ökar risken för åderförkalkning och hjärtinfarkt. Nu visar en ny studie vid Lunds universitet att smör ger en betydligt lägre blodfettshöjning efter en måltid jämfört med olivolja. Skillnaden var tydlig hos framförallt män, medan den hos kvinnor var mer marginell. Den främsta förklaringen till smörets relativt låga blodfettss

https://www.diabetesportalen.lu.se/artikel/smor-ger-lagre-blodfetter-olivolja - 2025-10-03

Ymnigt guldregn över diabetesforskning

Läkemedelsföretaget Novo Nordisk donerar 885 miljoner danska kronor till universitetet i Köpenhamn och ett nytt center för grundläggande forskning om typ 2 diabetes, övervikt och hjärtkärlsjukdomar. Det är den största donationen någonsin i Danmarks historia. Kamp mot folksjukdomarPengarna, mer än 1,2 miljarder svenska kronor, ska fördelas över tio år. Det nya centret i Köpenhamn har namnet ”The No

https://www.diabetesportalen.lu.se/artikel/ymnigt-guldregn-over-diabetesforskning - 2025-10-03

Flytten till Sverige ökar diabetesrisken

Barn till invandrare från länder med låg risk för typ 1 diabetes drabbas oftare än förväntat av sjukdomen om de växer upp i högrisklandet Sverige. Något i den svenska miljön ligger bakom, menar forskarna. Ahmed Delli, forskare på Lunds Universitets Diabetescenter, har kartlagt vad som händer när ett barn flyttar från ett område med låg risk för typ 1 diabetes till ett område med hög risk som Sveri

https://www.diabetesportalen.lu.se/artikel/flytten-till-sverige-okar-diabetesrisken - 2025-10-03

New study: Parents' metabolic traits can affect the child's health over time

New research at Lund University shows that the biological parents’ genes affect the child's insulin function and capacity to regulate blood sugar levels and blood lipids in different ways. Such knowledge may be used to to develop preventive treatments that reduce the child's risk of developing type 2 diabetes and cardiovascular disease. Previous research by diabetes researcher Rashmi Prasad has sh

https://www.medicine.lu.se/article/new-study-parents-metabolic-traits-can-affect-childs-health-over-time - 2025-10-03

Fine-tuning neural circuits to heal the brain – Segerfalk lecturer Andres Lozano on next-gen neurosurgery

LONGREAD. He treats tremor with sound waves, is preparing to help paralyzed patients control a cursor with their thoughts and envisions a future where brain and machines talk to each other in both directions. Neurosurgeon and researcher Andres Lozano is pushing the boundaries of what is possible in the human brain – and doing it with both precision and imagination. “We are trying to discover the b

https://www.medicine.lu.se/article/fine-tuning-neural-circuits-heal-brain-segerfalk-lecturer-andres-lozano-next-gen-neurosurgery - 2025-10-03

More opportunities to test for Alzheimer’s using new analytical method

A simpler method of analysing blood samples for Alzheimer’s disease has been tested in a large multicentre study, led by Lund University in Sweden. “This is a major step in bringing simple blood tests for Alzheimer’s disease into the healthcare system globally,” say the researchers behind the study. In brief:The blood-based marker (P-tau217) may start to change several years before the onset of Al

https://www.medicine.lu.se/article/more-opportunities-test-alzheimers-using-new-analytical-method - 2025-10-03

From molecule to patient – Six promising projects to advance Parkinson's research

What role does an inflammatory protein have in disease development? Which neuronal circuits cause different symptoms? How may diabetes affect Parkinson’s disease? Can motor signs be identifies early in individuals at risk for the disease? And how should patients in very advanced disease stages be treated to maintain their quality of life? These questions may soon have answers thanks to several ong

https://www.medicine.lu.se/article/molecule-patient-six-promising-projects-advance-parkinsons-research - 2025-10-03

Simple medication can save the lives of cardiac patients

Patients suffering from myocardial infarction who receive early add-on lipid-lowering medication have a significantly better prognosis than those who receive add-on treatment late, or not all. Based on the results of a study from Lund University in Sweden, many new heart attacks, strokes and deaths could be prevented. Cardiovascular disease is by far the most common cause of death worldwide, and m

https://www.medicine.lu.se/article/simple-medication-can-save-lives-cardiac-patients - 2025-10-03

Lund Stem Cell Center welcomes a new leadership team

The Lund Stem Cell Center at Lund University welcomes the beginning of a new chapter with the appointment of its new leadership team. As of January 1, 2025, Professor Malin Parmar has assumed the role of Director, with Associate Professor Göran Karlsson stepping in as Deputy Director. Together, they bring decades of expertise, deep connections to the Lund research community, and a shared vision fo

https://www.medicine.lu.se/article/lund-stem-cell-center-welcomes-new-leadership-team - 2025-10-03

Protein changes reveal diseases

Researchers at Lund University have developed a new method to determine how the composition of proteins in blood changes in response to disease or organ damage. This could provide a deeper understanding of how diseases affect the body and be used to discover new biomarkers in the blood to aid in diagnosing complex medical conditions. Our organs consist of a variety of specific proteins that are vi

https://www.medicine.lu.se/article/protein-changes-reveal-diseases - 2025-10-03

Higher success rate using a simple oral swab test before IVF

Researchers at Lund University in Sweden have conducted a clinical study to show how a woman’s genetic profile provides information on which hormone treatment is most effective for in vitro fertilisation (IVF). The researchers have now developed a simple oral swab test that shows which hormone therapy is the best option for IVF treatment About 15 per cent of all couples of reproductive age are inv

https://www.medicine.lu.se/article/higher-success-rate-using-simple-oral-swab-test-ivf - 2025-10-03

8.3 million euros for doctoral programme in regenerative medicine and ATMP

Lund University in Sweden has been awarded an EU grant of 8.3 million euros for a new international doctoral programme in regenerative medicine and advanced therapy medicinal products. The aim is to improve the environment for regenerative medicine and ATMPs in Europe and facilitate cooperation between research and clinical application. It started as an idea at the Lund Stem Cell Center to train a

https://www.medicine.lu.se/article/83-million-euros-doctoral-programme-regenerative-medicine-and-atmp - 2025-10-03

Lund University's virus centre inaugurated with symbolic demolition of giant virus

Lund University Virus Centre (LUVC) holds festive inauguration (May 27). There was no ribbon-cutting ceremony, but instead a symbolic demolition of a 3D-printed giant virus marked the official opening of the virus centre.Three deans—current and former—as well as professors who have succeeded one another at the Faculty of Medicine and played key roles in bringing LUVC to life, attended the ceremony

https://www.medicine.lu.se/article/lund-universitys-virus-centre-inaugurated-symbolic-demolition-giant-virus - 2025-10-03

New gene variants significantly increase the risk of blood clots

Blood clots can form in both arteries and veins. However, the reasons behind them differ, as do the consequences and the chances of preventing blood clots. In Sweden, almost half of all cases of venous thrombosis have a genetic explanation. A team of researchers from Lund University in Sweden has now discovered three gene variants that increase the risk of blood clots in the leg by up to 180 perce

https://www.medicine.lu.se/article/new-gene-variants-significantly-increase-risk-blood-clots - 2025-10-03

Link identified between low-fibre diet and the more dangerous type of atherosclerotic plaque in the coronary arteries

A Swedish multi-centre study led by researchers at Lund University shows a link between low fibre consumption and the presence of unstable or high-risk plaque in coronary arteries – the type of plaque that can trigger blood clots and cause heart attacks. The study also links dietary pattern to the composition of the plaques, i.e. how potentially dangerous they are. Using advanced cardiac imaging,

https://www.medicine.lu.se/article/link-identified-between-low-fibre-diet-and-more-dangerous-type-atherosclerotic-plaque-coronary2 - 2025-10-03

How to turn research ideas into a real-world impact

Professors Carl Borrebaeck, Thoas Fioretos, Lao Saal and Åke Borg share their experiences in transforming groundbreaking research into diagnostic tools, treatments, and biotech companies. From navigating commercialization strategies and securing long-term funding to building strong teams and mentoring future innovators, they reflect on what it truly takes to make science matter—outside the lab. Th

https://www.medicine.lu.se/article/how-turn-research-ideas-real-world-impact - 2025-10-03