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Focusing on chronic lung disease

The Lung Bioengineering and Regeneration research group is made up of about 15 researchers focusing on chronic lung disease. The group’s work includes the development of different methods to study disease models for conditions such as COPD and pulmonary fibrosis. One of the researchers, John Stegmayr, has been awarded SEK 700,000 from the Carl Tesdorpf Foundation to expand research into idiopathic

https://www.medicine.lu.se/article/focusing-chronic-lung-disease - 2025-10-29

Learning more about the endocrine system could lead to fewer cases of type 2 diabetes and obesity

How much water do we need to drink to stay healthy? How do different diets affect our metabolism? Studies of various hormones in the body are providing diabetes researchers with new answers to these questions. The goal is to develop individualized treatments and dietary recommendations that could lower the risk of developing obesity and diseases such as type 2 diabetes. The endocrine system and th

https://www.medicine.lu.se/article/learning-more-about-endocrine-system-could-lead-fewer-cases-type-2-diabetes-and-obesity - 2025-10-29

ERC grants for research on diabetes and immunotherapy

Two innovation-driven research projects at Lund University have been awarded a Proof of Concept Grant by the European Research Council, ERC. They relate to biomarkers for predicting who benefits from metformin in the treatment of type 2 diabetes and new technology to enable powerful and focused therapies for the treatment of solid tumours. Charlotte Ling has been awarded an ERC Proof of Concept Gr

https://www.medicine.lu.se/article/erc-grants-research-diabetes-and-immunotherapy - 2025-10-29

Metabolic health plays role in obesity-related cancers

For up to 40 years, nearly 800,000 people from Sweden, Norway and Austria have been tracked based on how their BMI and metabolic health – that is, their blood pressure, blood glucose levels and blood fats - affect the risk of suffering from obesity-related cancers. The study shows that those who are metabolically unhealthy are at a higher risk of certain forms of cancer, regardless of their body w

https://www.medicine.lu.se/article/metabolic-health-plays-role-obesity-related-cancers - 2025-10-29

Complications in pregnancy linked to increased risk of heart disease

Certain complications during pregnancy bring an increased risk of heart disease later on. However, there is still much to learn about how arteriosclerosis develops between pregnancy and heart disease later in life. A large new study led by researchers from Lund University in Sweden shows that narrowing and calcification of the blood vessels of the heart are more common in women previously affected

https://www.medicine.lu.se/article/complications-pregnancy-linked-increased-risk-heart-disease - 2025-10-29

PAX5 – a gene strongly associated with impaired insulin secretion in type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if it is possible to use the genetic CRISPR/Cas9 scissors to correct the gene’s activity. The research team’s scientific paper was published in the Journal of Clinical Invest

https://www.medicine.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-10-29

Mapping aquaporins, water channels in cell membranes

Modern imaging techniques allows researchers to map the structure of the smallest components of cells, such as proteins. By understanding what proteins look like and how they interact with their surroundings, researchers can find keys to more effective drug therapies. In a study led from Lund University, researchers have mapped the structure of a channel in the cell membrane that regulates the tra

https://www.medicine.lu.se/article/mapping-aquaporins-water-channels-cell-membranes - 2025-10-29

New insights into foetal development may protect against leukaemia

During the foetal stage, a number of so-called cell programs run that are vital to the development of the foetus. In a study published in Cell Reports, researchers from Lund University demonstrate that one of these foetal programs appears to protect against acute myeloid leukaemia (AML). “We have used an experimental mouse model that always results in this type of leukaemia. The interesting thing

https://www.medicine.lu.se/article/new-insights-foetal-development-may-protect-against-leukaemia - 2025-10-29

First patient receives milestone stem cell-based transplant for Parkinson’s Disease

On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund University and it is now being tested in patients for the first time. The transplantation product is generated from embryonic stem cells and functions to replace the dopamine nerve cells which are lost in the p

https://www.medicine.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-10-29

Smart microscopy works out where to take the picture

Is it possible to know exactly where to point a microscope in order to capture the precise moment a bacterium or a virus infects a cell? In order to take high resolution microscopic images of living biological material, you need to know exactly where to point the microscope. Researchers at Lund University in Sweden have now developed a software solution for smart, data-driven microscopy, which mak

https://www.medicine.lu.se/article/smart-microscopy-works-out-where-take-picture - 2025-10-29

What makes blood stem cells transform? Regulation of RNA splicing may be an answer

Researchers at Lund University Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major nexus of gene expression regul

https://www.medicine.lu.se/article/what-makes-blood-stem-cells-transform-regulation-rna-splicing-may-be-answer - 2025-10-29

ERC Advanced Grant for Alzheimer's Research

Three researchers at Lund University in Sweden, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. One of these researchers is neuroscientist Oskar Hansson, who will use blood tests for rapid screening of drugs in the treatment of Alzheimer’s disease. The European Rese

https://www.medicine.lu.se/article/erc-advanced-grant-alzheimers-research - 2025-10-29

Obstetricians more emotionally stable than most

Swedish obstetricians and gynecologists are noticeably more emotionally stable and conscientious compared to the majority of the Swedish population. Based on the doctors' personalities, their decision-making styles differ in emergency situations. The research study from Lund University is now published in Scientific Reports. Personality is usually summarized in five traits - the so-called "big fiv

https://www.medicine.lu.se/article/obstetricians-more-emotionally-stable-most - 2025-10-29

Revealed: Molecular “superpower” of antibiotic-resistant bacteria

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study led from Lund University in Sweden now shows how two molecular mechanisms can work together make the bacterium extra resistant. “Using this

https://www.medicine.lu.se/article/revealed-molecular-superpower-antibiotic-resistant-bacteria - 2025-10-29

Cocktail of modified antibodies provides strong effect against SARS-CoV-2

Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus. The modified antibodies have been tested in human cells and with mice. Many antibodies used to treat covid infection during the pandemic have been so-called neutralizin

https://www.medicine.lu.se/article/cocktail-modified-antibodies-provides-strong-effect-against-sars-cov-2 - 2025-10-29

Hello there, Anil Seth…

Almost 14 million viewers have watched Anils Seth’s TED Talk “Your brain hallucinates your conscious reality”. In the beginning of May, he visits Lund University and Neuroscience Day to give this year's prestigious Segerfalk lecture. We meet on zoom for a conversation about AI, the mystery of consciousness and – of course – to find out what he knew about Sweden. … how would you explain consciousne

https://www.medicine.lu.se/article/hello-there-anil-seth - 2025-10-29

Understanding the sensitivities of body and mind: Open lecture with the 2023 honorary doctors of the Faculty of Medicine

A Nobel laureate and a pioneer have been appointed honorary doctors 2023 at our faculty. On May 24, they offer their insights into the sensitivities of body and mind in an open lecture. In this lecture you will hear the 2023 honorary doctors of the Faculty of Medicine, Nobel laureate professor David Julius and professor Rita Charon each talk about their research and what it has taught them about t

https://www.medicine.lu.se/article/understanding-sensitivities-body-and-mind-open-lecture-2023-honorary-doctors-faculty-medicine - 2025-10-29

Superstars coming to Lund for drug and pharmaceutical symposium

Several Nobel laureates, renowned scientists, and successful biotech entrepreneurs are coming to Lund in May to participate in the Lund Spring Symposium, an international symposium on drug research. Medications are the physician's primary tool when treating their patients, and understanding how drugs work is fundamental to being a good doctor, according to Lars Grundemar, adjunct professor of clin

https://www.medicine.lu.se/article/superstars-coming-lund-drug-and-pharmaceutical-symposium - 2025-10-29

New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atheroscler

https://www.medicine.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-10-29