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High-grade serous ovarian cancer (HGSOC) is a major health concern for women due to its subtle onset, aggressive progression, high recurrence rate, and resistance to standard therapies. Olaparib, a PARP inhibitor, is currently used as maintenance therapy following removal of tumors. C26A6 is a promising therapeutic which has been shown to inhibit breast cancer progression in mouse models by disrup
Lipid nanoparticles (LNPs) are vesicular structures composed of phospholipids commonly used in vaccine formulations due to their ability to protect and encapsulate mRNA for efficient delivery to target cells. This delivery system was pivotal for the rapid development of COVID-19 mRNA vaccines. Efficient mRNA delivery depends on the particle size and stability of LNPs, making these key parameters t
This study examines determinants of child marriage among women in Zimbabwe using data from the 2015 Demographic and Health Survey and the 7th wave of the World Values Survey. The purpose is to assess the effect that individual-level empowerment, and community-level social norms have on child marriages in Zimbabwe, testing if: H1 Higher levels of empowerment on an individual level is associated wit
The Healthcare Strike 2024 : An Oral History. This bachelor thesis explores the effect of the 2024 strike by the Swedish Association of Health Professionals on the subjectivity of its participants. Through oral history as method and theory, recorded interviews with a strategic selection of informants have been conducted. All informants are nurses and union members, but with varying degrees of unio
This thesis investigates the adaptive reuse of Vagnsverkstaden, a former railway maintenance hall in Malmö’s Lokstallarna. The project explores how this early 20th-century industrial structure can be transformed into a multifunctional civic space, while preserving its material and historical character. Using site analysis, theoretical frameworks, and case study comparisons, the proposal introduces
This Master’s thesis project tackles the challenge of engaging parents and children in shared reading by transforming everyday waiting areas into inviting reading spaces. Although parents know that reading is important, many struggle to find the time amidst daily pressures and feel overwhelmed by the demands of modern life. By providing a calm reading space in environments where children and paren
Syftet med studien var att undersöka om det finns en relation mellan upplevelsen av destruktivt ledarskap från närmsta chef och upplevelsen av stress respektive utbrändhet hos anställda. Studien undersökte även om det finns en relation mellan aktivt respektive passivt destruktivt ledarskap och stress respektive utbrändhet. Slutligen syftade studien till att undersöka om det finns en relation mellaThe purpose of the study was to investigate whether there was a relationship between the experience of destructive leadership by the immediate manager and the experience of stress and burnout among employees. The study also investigated whether there was a relationship between active and passive destructive leadership and stress and burnout. Finally, the study aimed to investigate whether there wa
Att kunna identifiera outnyttjad byggrätt är en angelägenhet hos såväl privata som offentliga aktörer. För privata aktörer uppstår detta behov exempelvis vid nybyggnadsprojekt och för offentliga kan ett annat behov istället vara att ha bättre koll på sin planberedskap. Att söka och beräkna byggrätten manuellt kan ta tid och för privata aktörer kan detta även leda till missade möjligheter. Ett digiBeing able to identify unused development rights is of interest for both private and public actors. For private actors, this need arises, for example, in new construction projects, and for public actors, another need may instead be to have better control over their planning readiness. Searching and calculating development rights manually can be time consuming and for private actors this can also l
One of the major contributors to the increasing complexity of integrated circuits, is the datapath logic, responsible for data transformations and manipulations. As performance demands increase, the complexity of these datapath logic increases, making the functional verification both tedious and expensive. A single undetected bug in this logic can compromise the system integrity, highlighting th
This thesis develops an application-oriented framework to identify and predict residential demand-side flexibility from the temporal structure of electricity use, rather than energy totals. We construct structure-based, price-aligned labels that track shifts between peak and off-peak hours, and train three complementary models: a next-day behavioral classifier (M1) for short-horizon operations, a
Lithium-ion batteries are widely used and remain the dominant energy storage technology for modern electronics and electric vehicles. Despite their widespread adoption, these batteries pose safety risks, including fire hazards and thermal runaway. One aspect that has received relatively little attention in current research is the formation and impact of fluorinated compounds during battery degrada
Denna uppsats behandlar de rättsliga frågor som uppstår när konserter och idrottsevenemang spelas in, laddas upp eller livestreamas. Bakgrunden är att sådana videor ofta laddas upp på internet, vilket aktualiserar både upphovsrättsliga och avtalsrättsliga frågor. Syftet med uppsatsen är att analysera rättsläget kring inspelning och tillgängliggörande av konserter och idrottsevenemang. Metoden soThis thesis addresses the legal issues that arise when concerts and sporting events are recorded, uploaded or livestreamed. The background is that such videos are often uploaded to the internet, which raises both copyright and contract law questions. The purpose of the thesis is to analyse the legal situation regarding the recording and making available of concerts and sporting events. The method
This thesis explores how bilingual and trilingual children aged 7–11 develop their English pronunciation in an international school where English is the main language of learning and play. Recordings from a storytelling task were rated for accent and comprehensibility, and background data from parental questionnaires provided detailed language profiles. Analyzing these data, it examines (a) whethe
Modern telecommunications equipment places increasing demands on energy efficiency, driven by both environmental concerns, rising electricity costs, and the strain on national power grids. This thesis investigates practical ways to reduce power consumption in radios, particularly in the downlink digital signal processing chain. Our findings were tested on two platforms, a validation board and an i
An exploration of perspectives in art through technology, by way of Graham Harman
This thesis extends the novel model of reference [1] to enable the description of odd-even and odd-odd nuclei, as well as negative-parity states of even-even nuclei. The method employs quasi-particle blockings of Hartree-Fock-Bogoliubov states to represent states with an odd number of particles using states with an even number of particles. The Bloch–Messiah decomposition for odd nucleon states is
This explorative thesis observes how European integration was framed in Lithuanian mass media in the years leading to the accession to the European Union, using it as a case study in the Central Eastern European region entering the EU in 2004. It is situated in the context of the emergence of the concept of European identity in the 1970s expressing the need for European Union countries to develop
In order to design and investigate the effects of vegetable oil based enzymatically produced liquid crystalline phases (LCPs), oat oil with 15% and 50% polar lipids contents (PL15, PL40) and with different storage conditions were incubated with Lipozyme TL and CalB. PL40 based LCPs were further investigated incorporating 1-10% aspartame (ASP) or ibuprofen (IBU) and all of the LCPs samples were ana
This thesis explores the spatial distribution of trees in the LPJ-GUESS dynamic global vegetation model and proposes some modification to improve ecological realism. In the standard version of LPJ-GUESS, the model simplifies forest dynamics by averaging individuals into cohorts and disregarding competition, canopy interactions or resource allocation completely. To improve this, a newer version was
