To investigate the role of protein kinase C delta (PKC delta) in angiotensin II-induced facilitation mechanisms of hypoxic neuronal damage and whether candesartan, an AT1 receptor antagonist, can suppress these mechanisms, we performed in vitro experiments which were free from vascular components using PC12 cells under hypoxic (12 h)/reoxygenation (0-48 h) conditions. Angiotensin II apparently inc

Kritisk granskning av det svenska mottagandet av Martin Scorseses Kristi sista frestelse ((The Last Temptation of Christ, 1988).

For a cathode duct of a proton-exchange membrane fuel cell, a three-dimensional analysis method is further developed to include two-phase, multicomponent gas and heat transport processes. A set of momentum, heat transport, and gas species equations is solved for the whole duct by coupled source terms and variable thermophysical properties. The effects of the electrochemical reactions on the heat g

In this paper, a new frequency offset correction approach for OFDM is proposed to track a wider range of offsets than conventional proposals, without devoting specific pilot symbols for synchronization. This can be attained since, in coherent OFDM, channel estimation is usually performed employing pilot-symbol assisted-modulation (PSAM), based on inserting known symbols in the time-frequency grid.

The effects of genetic variation on molecular functions predisposing to type 2 diabetes are still largely unknown. Here, in a specifically designed diabetes model, we couple separate gene loci to mechanisms of P-cell pathology. Niddm1i is a major glucose-controlling 16-Mb region in the diabetic GK rat that causes defective insulin secretion and corresponds to loci in humans and mice associated wit

Popular Abstract in Swedish Som ett skepp uti vilda havet, den kristna församlingen i ärkebiskop Laurentius Petris verk I 1593 års Uppsala mötes "förening om läran, ceremonier och kyrkotukt" finns följande avsnitt : Thernäst bejake och vederkännes vi oss alldeles vele holle vidh the Apostoliske, Niceniske och Athanasii symbola, såsom och vidh then äldste, rätte och oförrandrede Ausburgiske confeThe aim of this thesis is to present the ecclesiology of Laurentius Petri, a former student at Wittenberg who was archbishop of Uppsala from 1531 to his death 1573. He had a decisive role in the founding of the Church of Sweden, especially through his Swedish Church Ordinance(1571). Nevertheless most of his seventy-three writings are little known and have been rarely studied. Chapter one starts by

Agonist-induced activation of smooth muscle involves a rise in intracellular Ca(2+) concentration and sensitization of myosin light chain phosphorylation to Ca(2+). Sr(2+) can enter through Ca(2+) channels, be sequestered and released from sarcoplasmic reticulum, and replace Ca(2+) in activation of myosin light chain phosphorylation. Sr(2+) cannot replace Ca(2+) in facilitation of agonist-activate

The mechanical effects of the intermediate filament protein desmin was examined in desmin deficient mice (Des-/-) and their wild type control (Des+/+). Active force generation was determined in intact soleus muscles and in skinned single fibres from soleus and psoas. A decreased force generation of skinned muscle fibres from Des-/- mice and a tendency towards decreased active force in intact soleu

Popular Abstract in Swedish Denna rapport handlar om hur framväxten av strategiskt betydelsefull kompetens kan föstås. Studien har tre teoretiska utgångspunkter hämtade ur resursbaserad strategiteori, strategisk human resource management samt organisatorisk inlärning. Genom en empirisk fallstudie av det snabbväxande högteknologiföretaget Axis Communications utvecklas en analyrsram genom vilken fraThe purpose of this thesis is to introduce the concept of distinctive competence in a multi-theoretical setting, consisting of the resource-based view, strategic human resource management and organizational learning, in order to develop a theoretical framework for better understanding of the dynamic side of distinctive competence. The empirical part of the study consists of an in-depth case study

Objective: An inability of the nervous system to fully activate the muscle is one factor that can contribute to age-related muscle weakness. Superimposed electrical stimulation can be used to determine voluntary muscle activation (VA). The aim of this study was to assess VA of the quadriceps muscle in healthy older and younger subjects. Design: Electrical stimulation causes moderate discomfort in

Background The design of the Exeter stem may facilitate distal migration, but radiostereometric analysis (RSA) studies have been limited to 2 years of follow-up. Patients and methods We followed migration of the Exeter femoral stems in 22 primary hip arthroplasties for 5 years with RSA. Results All stems migrated distally and the median migration at 2 years was 1.34 mm, while at 5 years it was 1

In this study the field effects on electrochemic ally controlled silicon etching in KOH during three- and four-electrode pn etch-stop have been investigated. When a p-doped bulk area is surrounded by n-doped silicon and the n-doped silicon is electrochemic ally passivated, small lines of bulk silicon in between the n-doped silicon would not etch. The size of the bulk silicon that did not etch coul

Popular Abstract in Swedish De nu gällande trafikpolitiska principerna för kostnadsansvaret lades fast i 1988 års trafikpolitiska beslut (Regeringens proposition 1987/88:50 om trafikpolitiken inför 1990-talet). Utgångspunkten för kostnadsansvaret är trafikavgifter på samhällsekonomiska villkor med syfte att ge rätt beteendesignaler på transportområdet. Från denna utgångspunkt har kostnadsansvaret Transport is a key factor for economic growth. It has enabled both the economic scale of production and an increase in competition. No one can question this role of transportation. There is, however, a back-side to the coin: the environmental challenge. Present trends show that transportation is not compatible with sustainable development. The need to internalise the external effects from trans-po