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CO2 elimination at varying inspiratory pause in acute lung injury
Previous studies have indicated that, during mechanical ventilation, an inspiratory pause enhances gas exchange. This has been attributed to prolonged time during which fresh gas of the tidal volume is present in the respiratory zone and is available for distribution in the lung periphery. The mean distribution time of inspired gas (MDT) is the mean time during which fractions of fresh gas are pre
Orthostatic hypotension and low blood pressure in organic dementia: a study of prevalence and related clinical characteristics
OBJECTIVE: To determine the prevalence of orthostatic hypotension (OH), low blood pressure and dizziness, falls and fractures in patients with organic dementia. DESIGN: We prospectively studied 151 patients, assessing the prevalence of OH, hypertension, heart disorders, diabetes mellitus and the use of medication possibly associated with OH. SETTING: The patients were admitted to our psychogeriatr
Reinstitutionalisation in mental-health care: comparison of data on service provision from six European countries
Objective To establish whether reinstitutionalisation is occurring in mental health care mid, if so, with What variations between Western European countries. Design Comparison of data on changes in service provision. Setting Six European countries with different traditions of mental health care that have all experienced deinstitutionalisation since the 1970s - England, Germany, Italy, the Netherla
On open shortest path first related network optimisation problems
The paper deals with flow allocation problems in IP networks using open shortest path first (OSPF) routing. Its main purpose is to discuss and propose methods for finding settlements of OSPF link weight system realising the assumed demand pattern for the given network resources (links capacities). Such settlements can result in a significantly better network performance, as compared with the simpl
An approach towards surface imprinting of the enzyme ribonuclease A
An Adsorbent showing enhanced selectivity for the enzyme RNase A was prepared by a surface imprinting procedure based on metal coordination. A metal chelating monomer, N-(4-vinyl)-benzyl iminodiacetic acid, was polymerized onto methacrylate-derivated silica particles in the presence of RNase A and metal ions. Lysozyme and RNase A were separated on the adsorbent used as stationary phase in high-per
Subchronic toxicity of Baltic herring oil and its fractions in the rat I: Fractionation and levels of organohalogen pollutants
Baltic herring (Clupea harengus) oil was extracted and fractionated. To examine the contribution to toxicity and biological effects of different halogenated organic pollutants, the herring oil and the fractions were mixed into pelleted food and given to Sprague-Dawley female rats at three levels, corresponding to a human intake of 1.6, 8.2 and 34.4 kg fish per week. Herring oil, its fractions, as
“Otiosorum hominum receptacula”: Orthodox Religious Houses in Ingria, 1615–52
The essay collects and analyses sources on the Russian Orthodox monasteries of the Swedish province of Ingria (Ingermanland). These houses have rarely been treated; their very existence is largely unknown among specialists, although they are the only Orthodox religious houses to have existed in Scandinavia before the mid-20th century, apart from those of post-1809 Finland. On the basis of printe
Repulsion between oppositely charged surfaces in multivalent electrolytes
In answer to recent experimental force measurements between oppositely charged surfaces we here reproduce the repulsion in the presence of multivalent salt using Monte Carlo simulations within the primitive model. Our osmotic pressure curves are in good agreement with experimental results. In contrast with Poisson-Boltzmann calculations, both repulsion and charge inversion are seen in the simulati
Elimination of S100B and renal function after cardiac surgery
OBJECTIVES: To determine the biologic half-life of the S100B protein and to investigate if the elimination of S100B depends on glomerular filtration rate (GFR). DESIGN: Prospective human study. SETTING: University hospital. PARTICIPANTS: Sixteen patients who underwent cardiac surgery with cardiopulmonary bypass. INTERVENTIONS: Shed mediastinal blood (autotransfusion) was returned to the patients p
Structured patient-clinician communication and 1-year outcome in community mental healthcare - Cluster randomised controlled trial
Background Patient-clinician communication is central to mental healthcare but neglected in research. Aims To testa new computer-mediated intervention structuring patient-clinician dialogue (DIALOG) focusing on patients' quality of life and needs for care. Method In a cluster randomised controlled trial, 134 key workers in six countries were allocated to DIALOG or treatment as usual; 507 people wi
Brachioradial pruritus is associated with a reduction in cutaneous innervation that normalizes during the symptom-free remissions.
Background: There has been a controversy regarding the cause of brachioradial pruritus: is it caused by a nerve compression in the cervical spine or is it caused by a prolonged exposure to sunlight? Objective: The purpose was to study clinical features of patients with brachioradial pruritus and to compare the cutaneous innervation in punch biopsies from the itchy skin of patients with the age-mat
Nephrogenic adenoma of the urethra: an unusual cause of hematuria in the child
The authors describe a 9-year-old boy who had an accident with his bicycle. He presented with hematuria a few weeks later, and cystoscopy results showed a polypod lesion near the veru montanum. The lesion was resected, and histologic examination showed a nephrogenic adenoma (NA), which recurred 6 years later with hematuria. NA is a rare lesion in a child's urethra and can be a source of hematuria.
Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells
Tamoxifen (Tam) is widely used in chemotherapy of estrogen receptor-positive breast cancer. It inhibits proliferation and induces apoptosis of breast cancer cells by estrogen receptor-dependent modulation of gene expression, but recent reports have shown that Tam (especially at pharmacological concentrations) has also rapid nongenomic effects. Here we studied the mechanisms by which Tam exerts rap
An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport
The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol. 116:727-735, 1973). In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport. The product of the azlB gene is an Lrp-like protein that negatively regulates
Remembering childhood atopic dermatitis as an adult: factors that influence recollection
Background: Atopic dermatitis (AD) is common in the population, and studies have shown that the disease is on the increase. Studies based on hospital records reflect selected populations and may miss less severe cases of AD, and the use of self-reported questionnaires has the drawback of recall bias. Objectives: To investigate some possible factors influencing recall bias when questionnaires are u
Cerebral glucose metabolism measured by positron emission tomography in term newborn infants with hypoxic ischemic encephalopathy
Total and regional cerebral glucose metabolism (CMRgl) was measured by positron emission tomography with 2-(F-18) fluoro-2-deoxy-D-glucose ((18)FDG) in 20 term infants with hypoxic ischemic encephalopathy (HIE) after perinatal asphyxia. All infants had signs of perinatal distress, and 15 were severely acidotic at birth. Six infants developed mild HIE, twelve moderate HIE, and two severe HIE during
Asymptotic solutions to the Smoluchowski's coagulation equation with singular gamma distributions as initial size spectra
Smoluchowski's coagulation equation is studied for the kernel K (u, v) = E(u(alpha)v(beta) + u(beta) v(alpha)) with real, non-negative alpha, beta and E, using gamma distributions with a singularity at zero volume as initial size spectra. As the distribution parameter of the gamma distribution, p, approaches its lower limit (p -> 0) the distribution becomes similar to pv(p-1) 1 for small v. Asympt
Trouble-Makers and Interactionism. Reconsidering Quarrels in Institutions for Juvenile Delinquents
The tense relationship between 'troublesome youth' and conventional society does not end with incarceration or institutional treatment. Rather, it is transformed into an abundance of interpersonal conflicts within incarceration and treatment. This article uses an interactionist perspective to critically assess five research approaches that account for these phenomena in various ways: 1) quarrels a
Electromagnetic corrections in partially quenched chiral perturbation theory
We introduce photons in partially quenched chiral perturbation theory and calculate the resulting electromagnetic loop-corrections at next-to-leading-order (NLO) for the charged meson masses and decay constants. We also present a numerical analysis to indicate the size of the different corrections. We show that several phenomenologically relevant quantities can be calculated consistently with phot