Objectives: There is a need for more specific biomarkers to diagnose and predict disease course in patients with axial spondyloarthritis (axSpA). This study aimed to study immunological plasma biomarkers at different time-points in radiographic (r)-axSpA patients overall and stratified by sex and compare these biomarker patterns in r-axSpA patients concerning disease phenotypes and disease activit

Objectives A rising incidence of septic shock as well as recommendations for early vasopressor initiation has increased the number of patients eligible for norepinephrine (NE). Traditionally, NE has been administered through central lines, in intensive care units, due to the risk of extravasation in peripheral lines. The aim of the current study is to determine the rate of complications and patien

Volatility, which indicates the dispersion of returns, is a crucial measure of risk and is hence used extensively for pricing and discriminating between different financial investments. As a result, accurate volatility prediction receives extensive attention. The Generalized Autoregressive Conditional Heteroscedasticity (GARCH) model and its succeeding variants are well established models for stoc

Background Elevated troponin levels are a sensitive biomarker for cardiac injury. The quick and reliable prediction of troponin elevation for patients with chest pain from readily available ECGs may pose a valuable time-saving diagnostic tool during decision-making concerning this patient population. Methods and results The data used included 15 856 ECGs from patients presenting to the emergency r

Introduction Nutritional education intervention during pregnancy is the process of teaching pregnant women about the importance of a healthy diet and how to make healthy food choices. It is an important part of public health and vital to preventing adverse birth outcomes. Therefore, synthesising available evidence on the effect of nutritional education intervention on birth outcomes is essential f

Personalized patient care has gained increasing attention in recent years. Precise drug dosing is critical for patient safety and good clinical outcomes, especially in intensive care units, where patients often are in critical conditions. Such treatments can include stabilizing blood pressure and heart rate or maintaining safe anesthesia levels. However, the inter-patient variability in the drug r

Background: Words are a natural way to describe mental states in humans, while numerical values are a convenient and effective way to carry out quantitative psychological research. With the growing interest of researchers in gaming disorder, the number of screening tools is growing. However, they all require self-quantification of mental states. The rapid development of natural language processing

If an atom of the host lattice in silicon is replaced by an atom belonging to the fifth group in the periodic table, the potential binding the extra electron to the impurity atom can, in most cases, be approximated by a hydrogen-like potential. 1 This gives rise not only to an energy level in the band gap for the impurity ground state, but, in addition, also to a series of excited states. In silic

Introduction: Ovarian cancer is a lethal disease with low survival rates for women diagnosed in advanced stages. Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. The β-galactoside-binding lectin, Galectin-3, is involved in different immune processes and has been associated with poor outcome in various cancer

I september 2022 blev den elev som dödat två lärare på Malmö Latinskola den första 18-åringen att dömas till livstids fängelse. Tova Bennet, juris doktor i straffrätt, menar att målet har flera aspekter som kan motivera en prövning i högsta instans.

This article critically examines the dual role of the Georgian Orthodox Church (GOC) as both a cultural guardian of national identity and a barrier to covenantal pluralism in Georgia. Drawing on legal-financial and comparative-historical analysis, it demonstrates how the GOC’s institutional dominance perpetuates systemic inequalities, including disproportionate state funding, inequitable property

Adopting technological innovations is crucial for organizations to survive in dynamic and competitive market scenarios. Moreover, it is essential to understand the customer needs and respond accordingly. The present research makes use of Technology-Organization-Environment (TOE) framework for Lean Six Sigma Integrated Industry 4.0 (LSSI) adoption. Scholarly literature shows that adopting LSSI dras

In this thesis, we provide a number of novel algebraic means of certifying stability and performance for linear systems constrained in various ways by cones. The purpose is mainly threefold: to provide mathematical statements with applicative potential, to unify seemingly dissimilar results in the literature and thereby increase understanding, and to advance the state of the art on dynamical syste