Severity assessment of patients with haemophilia A (HA) is traditionally based on FVIII activity (FVIII:C). Clinical phenotype of HA patients often differs between individuals with the same FVIII:C determined with clotting and chromogenic assays. The aim of this study was to assess the influence of the FVIII:C on thrombin generation (TG) assay parameters both in vitro and ex-vivo postinfusion plas

Loess soils cover vast areas in the arid and semi-arid regions of northern China. Due to the lack of reliable surface water and ground-water, rainwater harvesting has played a prominent role in farmers' domestic usage and agricultural irrigation. An economical arid valid type of water storage cistern with optimum design of components has been introduced to rural areas in the Loess Plateau. Differe

A fragment of the mitochondrial cytochrome b gene of avian malaria (genera Haemoproteus and Plasmodium) was amplified from blood samples of 12 species of passerine birds from the genera Acrocephalus, Phylloscopus and Parus. By sequencing 478 nucleotides of the obtained fragments, we found 17 different mitocholdrial haplotypes of Haemoproteus or Plasmodium among the 12 bird species investigated. On

In order to correlate behavioural deficits to lesion size and to reveal possible functional asymmetries in the rat brain, locomotor activity, rotation and sensorimotor integration to touch were studied in spontaneously hypertensive rats (SHR) subjected to right or left middle cerebral artery occlusion. Control and infarcted rats showed no difference in locomotor activity. Infarcted rats tended to

RATIONALE AND OBJECTIVES. During coronary arteriography the blood is replaced for a short period of time with a contrast medium (CM) solution. The CM may cause a risk of arrhythmias and ventricular fibrillation (VF). Previous investigations have shown that the addition of small amounts of sodium (10-30 mmol/L) to nonionic CM may decrease the risk of VF from these media. Calcium addition to nonioni

We report a theoretical study of the electronic structure of GaAs nanowhiskers, grown in the [111] direction with hexagonal cross section, based on a tight binding approach. It is shown that the band structure of the GaAs nanowhiskers shifts from a direct band gap to an indirect band gap when the lateral size of the nanowhiskers becomes smaller than a certain value. The effective masses of the ele

To mimic the two-signal requirements for T cell activation mediated by ligands, we exposed the superantigens SEA or SEE (signal 1) to T cells incubated with HLA-DR/LFA-3 or HLA-DR/137-1-CHO transfected cells (signal 2). LFA-3 costimulation was able to induce T cell proliferation as well as IFN-gamma and IL-4 production at similar levels as in cells induced by B7-1. Analysis of the CD28RE of the IL

Energy balances are analysed from a life-cycle perspective for biogas systems based on 8 different raw materials. The analysis is based on published data and relates to Swedish conditions. The results show that the energy input into biogas systems (i.e. large-scale biogas plants) overall corresponds to 20-40% (on average approximately 30%) of the energy content in the biogas produced. The net ener

The crustose lichenized fungi in the Acarosporaceae are splendid examples of organisms managing to survive in extremely harsh environments, such as highly mineralized rocks and low-pH habitats. Some representatives of the Acarospora smaragdula complex are known to accumulate substantial amounts of potentially toxic metals including iron and copper, resulting in populations with highly divergent co

The binding of a nitroxide spin-labeled analog of N-acetyllactosamine to galectin-3, a mammalian lectin of 26 kD size, is studied to map the binding sites of this small oligosaccharide on the protein surface. Perturbation of intensities of cross-peaks in the (15)N heteronuclear single quantum coherence (HSQC) spectrum of full-length galectin-3 owing to the bound spin label is used qualitatively to

To compare the effectiveness of individual support, group rehabilitation and a combination of the two in improving health-related quality of life (HRQOL) and psychological well-being in cancer patients during 24 months after diagnosis, as compared with standard care (SC). Furthermore, to compare the study sample and a random sample of the Swedish population with regard to HRQOL. A total of 481 con

The generation of proton beams from ultrathin targets, down to 20 nm in thickness, driven with ultrahigh contrast laser pulses is explored. the conversion efficiency from laser energy into protons increases as the foil thickness is decreased, with good beam quality and high efficiencies of 1% being achieved, for protons with kinetic energy exceeding 0.9 MeV, for 100 nm thick aluminum foils at inte

A coarse network of nerve fibres displaying immunoreactivity for vasoactive intestinal polypeptide (VIP) was found in the wall of the hepatic portal vein of the rabbit. Electrical field stimulation of the rabbit portal vein in vitro, in the presence of adrenergic and cholinergic blockade, caused a marked relaxation of the vessel and a release of VIP into the perfusate. Addition of VIP to the tissu

The issue of adverse health effects from dental amalgam and the concurrent low-dose exposure to inorganic mercury have been scrutinized by several Swedish expert groups during the past years. Only rarely have amalgam fillings in children been related to health effects. Experimental studies in genetically disposed animals have shown that low doses of inorganic mercury can induce autoimmune glomerul

Objective: To discuss terminology, radiological differential diagnoses and significance of magnetic resonance imaging (MRI)-detected subchondral bone marrow lesions (BMLs) of the knee joint. Methods: An overview of the published literature is presented. In addition, the radiological appearance and differential diagnosis of subchondral signal alterations of the knee joint are discussed based on exp