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Haploblocks are regions of the genome that coalesce to an ancestor as a single unit. Differentiated haplotypes in these regions can result from the accumulation of mutational differences in low-recombination chromosomal regions, especially when selective sweeps occur within geographically structured populations. We introduce a method to identify large well-differentiated haploblock regions (LHBRs)
Objectives Early detection of neurosensory injury among workers exposed to hand-arm vibration is crucial. The aim of our study was to evaluate the diagnostic test performance of clinical point-of-care testing using a tuning fork and temperature rollers in relation to vibrotactile and thermal quantitative sensory testing. Methods We recruited 225 vibration-exposed workers who underwent clinical poi
Understanding the structure of metal-ligand complexes is essential for catalyst design, materials development, and biochemical modeling. Metal carbonyls are especially relevant due to their diverse structures and electronic features. Here, we benchmarked seventeen density functionals (B3LYP, BP86, CAM–B3LYP, M06, M06L, PBE, PBE0, r2SCAN, r2SCAN–3c, revPBE, revTPSS, RPBE, TPSS, TPSS0, TPSSh, (Formu
A memlumor is an innovative neuromorphic luminescent device with a state-dependent photoluminescence quantum yield (PLQY) designed for optical neuromorphic computing applications. Metal halide perovskite memlumors leverage charge trapping and photodoping to modulate the PLQY, making it dependent on the excitation light history. Here, we demonstrate the ability of perovskite memlumors to classify t
OBJECTIVES: This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of acupuncture for the treatment of infantile colic.
Ledarskap har beskrivits som ett undflyende fenomen – en (positiv) lösning som kan kopplas till nästintill alla problem, men är svårt att fånga när det händer. Karisma, transformation och extraordinärisering utgör synsätt på ledarskap där särskilda individer tillskrivs extraordinära egenskaper, men de har inte fångat hur detta görs i vardagliga interaktioner. Ledarskap som praktik och ledarskap i Leadership has been described as a disappearing phenomenon – a (positive) solution that can be attached to almost any problem, yet it is difficult to capture as it happens. Charisma, transformation, and extra-ordinarization are perspectives on leadership where certain individuals are ascribed extraordinary qualities, but this is not captured analytically in everyday interactions. However, Leadersh
The Paris Agreement necessitates global net-zero emissions by mid-century, including steel industry emissions that currently amount to about 7% of global energy system emissions. In this article we review the literature on steel decarbonization. Steel industry emission mitigation measures include reduced demand through materials efficiency, increased high-quality recycling, and decarbonization of
This paper uses uncertainty generated by environmental change and climate crisis as a prompt to rethink the concept of vulnerability within disaster studies. Where some have sought to recover a latent political potential in vulnerability, a togetherness founded in the disclosure of insecurities to others, we argue that there is value in refusing to settle on any single meaning. This is explored di
Objective: To evaluate the causal effect of genetically predicted serum urate (SU) levels on the risk of overall and major site-specific cancers in individuals of European ancestry, using Mendelian randomization (MR) analysis. Method: Data from two population-based cohorts from southern Sweden, the Malmö Diet and Cancer Study (MDCS) and Malmö Preventive Project (MPP), and summary-statistics data f
High-performance X-ray detectors are essential for 3D X-ray imaging in computed tomography (CT), but conventional systems require high radiation doses to achieve fine resolution. All-In-One (AIO) Cu(I) halide complexes, capable of forming both ionic and coordinate bonds within a single structure, offer efficient scintillation at lower doses, yet their performance remains limited by nonradiative en
Introduction: Residual cognitive deficits are commonly reported by individuals in remission from depression, often affecting daily life functioning and mental health. To provide tailored and personalized cognitive enhancement interventions for this population, there is a need for a better understanding of the characteristics of those who benefit from such interventions. Therefore, this study aimed
This paper presents an integrated conodont biostratigraphy and carbon isotope chemostratigraphy for the Cambrian-Ordovician transition in western Zhejiang, southeast China. Eight conodont zones can be recognized, in ascending order the Westergaardodina cf. calix-Prooneotodus rotundatus, Proconodontus, Eoconodontus, Cordylodus proavus, Cordylodus intermedius, Cordylodus lindstromi, Cordylodus angul
Background: Employment rates are lower in adults with cerebral palsy (CP). Even though reduced manual ability is associated with limitations in daily activities, it is unclear whether employment rates are associated with manual ability in adults with CP. Objective: To analyze regular employment and employment rates (hours/week) in adults with CP and estimate their associations with manual ability
Inclusive urbanisation is being promoted in development discourse, and a scholarly debate is emerging, but the conceptualisation and empirical understanding of this process should be placed in relation to urbanisation trends. In sub-Saharan Africa more than a quarter of the urban population lives in small towns. These are predicted to experience the most rapid population growth in the coming decad
This chapter focuses on how to apply salutogenesis in practice in the context of health care, especially when designing interventions. The foundation for implementation is to understand and apply the core principles of salutogenesis and health promotion, hereby building capacity and strength in all involved, i.e.: the patients, participants, health professionals and relatives. The key salutogenic
Jordbruk och jordbruksomvandling är centrala i debatten om försörjning, utveckling och hållbarhet, särskilt i det globala syd där de förs fram som vägen till fattigdomsbekämpning, livsmedelssäkerhet och ekonomisk omvandling. Trots årtionden av reformer fortsätter jordbruksutvecklingen dock att ge ojämna och motstridiga resultat. Politik för social inkludering, landsbygdsomvandling och hållbarhet bAgriculture remains central to global debates on livelihoods, development, and sustainability, particularly across the Global South where it is widely promoted as a pathway to poverty reduction, food security, and economic transformation. Yet, despite decades of reform, agricultural development continues to generate uneven and contradictory outcomes. Policies framed around inclusion, rural transfo
