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Popular Abstract in Swedish Cellerna i blodet har en rad skilda funktioner, såsom att transportera syre, levra blodet vid behov eller att på olika sätt delta i vårt immunförsvar. Alla blodets celler härstammar från en s k stamcell som har förmåga att genom en rad förändringar mogna ut till vilken typ av cell som helst i blodsystemet. Leukemi är en sjukdom som drabbar blodet och som uppstår p g a aAcute myeloid leukemia (AML) is commonly associated with balanced chromosomal translocations. Characteristically, these translocations lead to the fusion of two unrelated genes, resulting in the expression of an aberrant fusion protein. t(8;21) is one of the most common translocations found in patients with AML. It results in the expression of the chimeric protein AML1-ETO. AML1 is a transcription

Despite improvements in therapy for children with type 1 diabetes, the prevalence of cardiovascular morbidity in adulthood due to accelerated atherosclerosis remains significant (1). Similar to other cardiovascular risk factors, the diabetic state facilitates arterial endothelial injury, a primary event in the pathogenesis of atherosclerosis (2). Although several pediatric studies have reported an

1. Five oligotrophic clear-water lakes on the Faroe Islands were studied during August 2000. Algal and bacterial production rates, community respiration, and CO2 saturation were determined. In addition, we examined the plankton community composition (phytoplankton and heterotrophic nanoflagellates) and measured the grazing pressure exerted by common mixotrophic species on bacteria. 2. High respir

BACKGROUND: In peritoneal dialysis, approximately 40% of the total osmotic ultrafiltration (UF) induced by glucose can be predicted to be due to "free" water transport across aquaporin-1 (APQ-1). Theoretically, it would be possible to assess the fraction of free water transport in the early phase of a hypertonic dwell, when UF rate is high and the relative contribution of Na+ diffusion is low. La

Man kan inte få reda på hur Jesus såg ut och exakt formulerade sig – t.o.m. ”Fader Vår” har vi i två rätt olika versioner. Hans egna verbala mönster skiner dock igenom evangelietraditionen, och går, liksom ett stort antal innehållsliga temata centrerade kring gudsriket, sannolikt tillbaka till Jesus själv. Två inflytelserika forskningsidéer, den om den obegränsade formbarheten i muntlig tradering

Popular Abstract in Swedish Diskussionen tar sin utgångspunkt i den klyfta som finns mellan, å ena sidan, stora delar av forsknings- och policy-världen och, å andra sidan, den verklighet som författaren stött på ute på den afrikanska landsbygden. Forskningsvärlden ser vattenresurser som en rent ekonomisk tillgång och småskaliga bönder beskrivs såsom vinstmaximerande individer, medan verkligheten äAllocation, control, and management of natural resources are issues that absorb researchers within both the social and natural sciences. This study deals with such research questions as well as with one of the most fundamental issues in Economic History – namely institutional change. The plot is set around continuity and change of property rights institutions governing water resources. The setting

The uptake of N-15-labelled alanine, ammonium and nitrate was studied in ectomycorrhizal morphotypes of intact Pinus sylvestris seedlings. PCR-RFLP analysis of the ITS-region of fungal rDNA was used to identify the morphotypes. Seedlings were grown in forest soil collected at an experimental site in southern Sweden. The treatments compared were a control, N fertilisation (600 kg N ha(-1) as urea),

OBJECTIVE: To compare the parental stress in the families of 2 year old extremely low birthweight (ELBW) infants with that in control families, and to compare the stress of mothers with that of fathers. METHODS: The study population included all parents of ELBW infants (birth weight < 1000 g and gestational age at least 22 gestational weeks) born between 1 January 1996 and 31 December 1997 in Hels

The behavior of DNA at different types of interfaces and how the formed structures DNA at an interface could be affected by cationic surfactant has been studied. Particular attention was paid to how the type of cationic surfactant and DNA (single or double stranded and length) affects the compaction/decompaction of DNA. Adsorption of DNA-cationic surfactant complexes is determined by a delicate ba

Electrical wiring of different types of pyranose oxidase (P20) (fungal wild type, recombinant wild type with a hexahistidine tag, mutant form E542K with a hexa-histidine tag) from Trametes multicolor, and recombinant P20 from Coriolus sp. overexpressed in Escherichia coli as well as of pyranose dehydrogenase (PDH) from Agaricus meleagris and Agaricus xanthoderma with an osmium redox polymer (poly(

STUDY DESIGN: By using roentgen stereophotogrammetric analysis in six patients having tantalum indicators implanted at a preoperative external fixation test, the mobility in the spondylolytic lumbosacral level and its adjacent segment could be studied before fusion and during the course of postoperative fusion consolidation. OBJECTIVE: To study the mobility effects on the segment adjacent to a lum

Popular Abstract in Swedish Miljöhänsyn vid produktutveckling hanteras alltmer inom ramen för arbetet i certifierbara miljöledningssystem exempelvis enligt den internationella standarden ISO 14001. Detta innebär att industrin i allt högre grad sätter mål och delegerar ansvar för en kontinuerlig förbättring av produkters miljöprestanda inom ramen för speciella miljöledningsprogram för produktutveckEnvironmental considerations in product development are increasingly dealt with in the framework of certified environmental management systems such as ISO 14001. This allows industry to set objectives and assign responsibility for continuous improvement for DFE activities and environmental performance of products in DFE management programs. This thesis presents a general model for DFE management p

Background. A national survey in 1996 showed insufficient routines for management of patients with mild head injuries in Norwegian hospitals. Since then, the Scandinavian Guidelines for Management of Mild Head Injuries have been published. Methods. A cross-sectional questionnaire survey of management practice was performed in all 59 hospitals in 2002. We compared the results with figures from 1996

Many attempts have been made for the last six decades to design defined media for species of the lactococcus group. The general outcome of the studies suggests that this group is heterogeneous with respect to specific requirements for nutrients. Lactococcal species are limited in various metabolic pathways. Early attempts to trace the required nutrients were not always successful because of the po

Antimicrobial peptides are effector molecules of the innate immune system. We recently showed that the human antimicrobial peptides alpha-defensin and LL-37 bind to glycosaminoglycans (heparin and dermatan sulphate). Here we demonstrate the obverse, i.e. structural motifs associated with heparin affinity (cationicity, amphipaticity, and consensus regions) may confer antimicrobial properties to a g

The role of protein kinase C (PKC) isoforms in the neural cell adhesion molecule (NCAM)-mediated neurite outgrowth was tested using a co-culture system consisting of fibroblasts with or without NCAM expression upon which either primary cerebellar granular neurones (CGN) or pheochromocytoma (PC12-E2) cells were grown. The latter transiently expressed various PKC isoforms and domains derived from se

Aims White right intracardiac thrombosis (IT) is a potential cause of pulmonary embolism (PE) similar to that of stroke in left-sided IT, its prevalence and prognostic significance has not been studied in the general population. The aim of this study was to assess the age- and gender-specific prevalence of IT and its relation to PE in a population-based autopsy cohort. Methods and Results Between

The transduction pathways coupling muscarinic receptors to induction of fos and jun genes were investigated in neuroblastoma SH-SY5Y cells. Stimulation with carbachol induced expression of c-fos, fosB, c-jun, junB, and junD. This effect was abolished by pretreatment with atropine, indicating an involvement of muscarinic receptors. These genes were also induced by activation of protein kinase C wit