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Nausea and emesis are common side effects of opioid drugs administered for pain relief in cancer patients. The aim of this study was to compare the anti-emetic efficacy and safety of ondansetron, placebo and metoclopramide in the treatment of opioid-induced nausea and emesis (OIE) in cancer patients. This was a multinational, multicentre, double-blind, parallel group study in which cancer patients
Popular Abstract in Swedish Av de industrier som kom att spela en viktig roll för den starka ekonomiska utvecklingen i Sverige från 1890-talet och framåt befann sig den moderna verkstadsindustrin i frontlinjen. Syftet med denna avhandling är att diskutera hur de teknologiska förändringar som präglade den andra industriella revolutionens inledande fas påverkade den relativa efterfrågan på yrkesskicSweden experienced a remarkable economic growth in the period 1890-1930, to a large extent due to a very successful adaptation of core elements of the Second Industrial Revolution such as electricity and mechanical engineering. Theoretically this thesis aims at discussing changes in the balance between the relative demand for skilled and unskilled labour during the first phase of the Second Indust
Popular Abstract in Swedish Familjen Mosasauridae omfattar en grupp storvuxna (3-13 m), vattenlevande reptiler som under ett geologiskt sett kort tidsavsnitt i kritperioden, om ca 25 miljoner år, snabbt tog över positionen som topp-predatorer i haven. Fossil av mosasaurier dyker först upp i lager avsatta för ca 90 miljoner år sedan. Under de följande årmiljonerna fick gruppen en närmast global utbMarine strata of latest early Campanian age (sensu germanico) in the Kristianstad Basin, Skåne (Scania), southern Sweden, have yielded a diverse mosasaur fauna comprising six to eight taxa, including Tylosaurus ivoensis, Clidastes propython, Hainosaurus minor n. sp., Halisaurus sternbergii, Platecarpus cf. somenensis, Platecarpus? sp., Dollosaurus sp., and possibly yet another mosasaurine or halis
Micronutrient concentrations in foliage and stemwood (including bark) of six European tree species (Betula pendula Roth., Quercus robur L., Fraxinus excelsior L., Fagus sylvatica L., Tilia cordata Mill. and Picea abies (L.) Karst.) planted on the same type of soil at six sites in three different countries were studied. Micronutrient concentrations in foliage were considerably higher than in stemwo
Urine sediments from 20 patients with urinary bladder carcinoma, and from 11 healthy individuals were investigated for their content of Lea and Leb active glycolipids. The investigation was restricted to blood group phenotype Le (a-b+). All individuals exhibited both Lea- and Leb-active glycolipids. In healthy individuals the ratio Lea/Leb was less than 1 in 10 out of 11 cases, whereas in patients
The aim of the study was to investigate the feasibility of mobilizing Philadelphia chromosome negative (Ph-) blood stem cells (BSC) with intensive chemotherapy and lenograstim (G-CSF) in patients with CML in first chronic phase (CP1). During 1994-1999 12 centers included 37 patients 556 years. All patients received 6 months' IFN, stopping at median 36 (1-290) days prior to the mobilization chemoth
Once activated, some T cells home to distinct sites in the body, such as the intestine and inflamed skin. Research in mice shows that dendritic cells in the gut produce a derivative of vitamin A, retinoic acid, that gives T cells directions.
Popular Abstract in Swedish Det finns en schablonblid av dopseden förr och nu. Lite karikerat skulle den kunna sägas se ut på följande sätt. Förr döptes alla barn. Skälen till att man döpte sina barn var djupt religiösa. Så kom baptismen och bröt barndopsseden. När baptisterna slutade döpa sina barn och sekulariseringesvågen blev allt starkare följde snart många efter. Idag döps barnen framfö alltFrom the time of the establishment of Christianity in Sweden to the middle of the Nineteenth Century all childeren were baptised. In Örebro, in central Sweden, the baptism custom was subsequently broken and weakend. Örebro is in many ways an extreme case. In 1910 only 82 percent of children were baptised. The old dodparent custom was almost extingct in 1910. The dissertation shows the course of ch
A new type of continuous, supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing specific fractionation and separation of human peripheral blood lymphocytes in a chromatographic format. The affinity adsorbent was used to design a novel cell separation strategy, which was based on the interaction of protein A from Staphylococcus aureus with cells bearing IgG antibodies on
A model based on the penetration theory has been developed to calculate the dynamic absorption rate of sulfur dioxide into a droplet of limestone slurry. The model includes both instantaneous equilibrium reactions and reactions with finite rates; limestone dissolution, sulfite oxidation, gypsum crystallization and the hydrolysis reaction of CO2. The model has been used to quantify the mass transfe
