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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured

The original chapter on adaptive-filter models addressed the issue of how far such models were consistent with experimental evidence. Here we consider one particularly important kind of evidence, that concerning the nature of the synaptic plasticity that underlies cerebellar learning. The basic decorrelation learning rule employed by the adaptive-filter model can be translated into spike timing-de

Popular Abstract in Swedish Denna avhandling undersöker hur vi använder visuell kontextinformation i samtal. Alla modeller över språkprocessning och kommunikation är ense om att visuell kontextinformation har en positiv nettoeffekt på förståelse och kommunikation. Trots detta är det inte klart genom vilka mekanismer denna kontextinformation verkar, eller om dessa mekanismer fungerar i situationer This dissertation is about the role of visual context information in communication. All accounts of language processing and communication agree that visual context is beneficial for understanding. Despite this, it is not clear through which mechanisms visual context works and whether these mechanisms also work in communication outside the lab setting. This dissertation aims to provide answers to t

The Department of Physical Geography and Ecosystem Science at Lund University is behind this site. We want as many people as possible to use our website. On this webpage, we describe how www.nateko.lu.se complies with the Swedish Act on Access to Digital Public Service, any known accessibility issues and how to report deficiencies to us so that we can rectify them. How accessible is the website? T

https://www.nateko.lu.se/accessibilitystatement - 2026-05-07

Sammanfattning “Bemanning” är idag ett inarbetat begrepp som innebär att ett bemanningsföretag anställer personal för att hyra ut dessa till att utföra arbete hos ett kundföretag. Det betyder att det normala anställningsförhållandet mellan en arbetsgivare och en arbetstagare får en tredje involverad part. Branschen har växt sedan början av 90-talet och har kommit att bli en allt mer etablerad del Abstract The staffing agency is today a well-known concept. Staffing agencies hire employees in order to rent them out to companies to fill vacancies on the market. This means that the traditional employment relationship between the employer and the employee now often involves a third party. The industry has grown since the early nineties and has become an established part of the labour market due

Denna uppsats behandlade ett typfall enligt vilket en person sökte anstifta ett mord, men den anstiftade förväxlade identiteten på måltavlan och mördade anstiftarens kumpan. Syftet med uppsatsen var att utreda och analysera vilket straffrättsligt ansvar anstiftaren har i scenariot. Till vägledande hjälpmedel presenterades två alternativa lösningsmodeller från juridisk doktrin: ekvivalensmodellen oThis thesis intended to examine a scenario regarding instigation of murder in which the instigated mistook an accomplice of the instigator for the intended victim. The purpose of the thesis was to assess the criminal liability of the instigator in that scenario. Two alternative models were presented within legal doctrine: the model of equivalence, and the model of specialty. According to the model

The orchid genus Nigritella is closely related to Gymnadenia and has from time to time been merged with the latter. Although Nigritella is morphologically distinct, it has been suggested that the separating characters are easily modifiable and subject to rapid evolutionary change. So far, molecular phylogenetic studies have either given support for the inclusion of Nigritella in Gymnadenia, or for

The purpose of the present article is to systematically investigate how people perceive collective threat and how such threat perceptions relate to political preferences. Existing threat taxonomies are mostly derived from top-down analyses and little attempt has been made to examine bottom-up how people spontaneously perceive threats. One area where this is of central importance is the relationshi

This website is run by The Centre for Environmental and Climate Research at Lund University. We want as many people as possible to be able use our website. This page describes how climate-kic.lu.se complies with the Swedish Act on Access to Digital Public Service, any known accessibility issues and how to report problems so that we can fix them. How accessible is this website?This website is partl

https://www.climate-kic.lu.se/accessibility-statement-climate-kicluse - 2026-05-07

This paper highlights the complexity and ambiguity regarding the phenomenon of so called honour-related violence and oppression and explores how these matters are taken into consideration in the field of social work. In order to explore this field of study we used qualitative research as the method of inquiry. Semi-structured interviews were conducted with six female social workers working with pe