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During the last decade, identification of the genes involved in familial forms of Parkinson's disease (PD) has advanced our understanding of the mechanisms underlying the development of different aspects of PD. However the available animal models still remain as the main limiting factor for the development of neuroprotective therapies that can halt the progression of the disease, through which we
The Garden Warbler is a classic subject for the study of Palaearctic-African bird migration strategies. Most studies have considered the situation close to the breeding areas, while the African and especially the sub-Saharan part of the species' migration have received comparatively little attention. Here we use autumn and spring ringing data from Nigeria and The Gambia to study the movements and
Alfonso Pecha (b. 1327, d. 1389), Bishop of Spanish Jaén from 1359 to 1368, went to Italy after his resignation. There he made St. Bridget’s acquaintance. Alfonso who was a man of great learning and wide experience became St. Bridget's trusted advisor and assisted her in propagating her great causes (the return of the papacy from Avignon to Rome, a reform of the Church, the founding of a new order
IKEA is a product developing company, known for putting packaging and logistics issues at the top of its agenda. At IKEA, the product and the packaging are developed concurrently with the aim of lowering the total cost from the supplier to the customer. During the years 2002 to 2004, a pckaging redesign project was conducted at IKEA. The purpose of the project was to redesign the packaging for an
Future wireless networks, the systems beyond 3G, will be a combination of different wireless systems. With only one terminal a user should be able to connect to different type of operators, technologies and systems. The issue is also to make the terminal staying online connected, when these changes are made. Both intrasystem handovers and intersystem handovers should be supported by such terminals
Consumers are pushing for higher data rates to support more services that are introduced in mobile applications. As an example, a few years ago video-on-demand was only accessed through landlines, but today wireless devices are frequently used to stream video. To support this, more flexible network solutions have merged in 4G, introducing new technical problems to the mobile terminal. New techniqu
Diffuse ultrasonic wave measurements used in structural health monitoring applications can detect damage in concrete. However, the accuracy is very susceptible to environmental variations. In this study, a large concrete floor slab was monitored using diffuse wave fields that were generated by continuous-wave transmissions between ultrasonic transducers. The slab was monitored for several weeks wh
BACKGROUND: Salmonella enterica serotype Enteritidis (SE) is considered to be one of the most potent pathogenic Salmonella serotypes causing food-borne disease in humans. Since a live bacterial vaccine based on surface display of antigens has many advantages over traditional vaccines, we have studied the surface display of the SE antigenic proteins, H:gm and SefA in Escherichia coli by the β-autot
The UN Sustainable Development Goal (SDG) 7 states that access to affordable, reliable, sustainable, and modern energy should be provided for all by 2030. The effects on socioeconomic development by access to safe, affordable, and clean electricity stands out as educational benefits, income improvement, and health progress. However, the electrification rate has been slow for sub-Saharan Africa and
The present review covers a wide scope of occupational heat stress related issues. The problematics related to climate change have placed heat exposure on the agenda. As a result, the research on heat effects has increased in recent years and a considerable amount of new material has become available. The literature includes general and specific reviews that focus on various heat-related aspects i
The research presented in this work represents reflections in the light of Julia Kristeva's philosophy concerning empirical data drawn from research describing the everyday life of people dependent on ventilators. It also presents a qualitative and narrative methodological approach from a person-centred perspective. Most research on home ventilator treatment is biomedical. There are a few publishe
The question whether students can be used as subjects in software engineering experiments is debated. In order to investigate the feasibility of using students as subjects, a study is conducted in the context of the Personal Software Process (PSP) in which the performance of freshmen students and graduate students are compared and also related to another study in an industrial setting. The hypothe
Computer control is entering all facets of life from home electronics to production of different products and material. Many of the computers are embedded and thus ``hidden'' for the user. In many situations it is not necessary to know anything about computer control or real-time systems to implement a simple controller. There are, however, many situations where the result will be much better when
In the first part I discuss general problems of program-evaluation. In spite of a lot of problems concerning the practice of evaluation it is becoming more and more popular in programs with ambitions to develop social change. This development rise important issues concerning the relation between politics and science as well as about the methods, the value-criteria and the theories that are in use.
In 2018, an AI system named by its creator DABUS (Device for the Autonomous Bootstrapping of Unified Sentience) was credited by its creator to have independently invented a neural flame and a fractal container. According to its creator, DABUS is a ‘sentient artificial general intelligence can replicate all aspects of human cognition, including perception, creativity, consciousness, and sentience’
Background: While HPV vaccination uptake in Sweden is quite high, at around 80%, vaccine hesitancy remains an issue in countries throughout Europe. The latter can be related to a contemporary context of increased contestation of expert knowledge and of a large share of information on health-related issues including vaccination today being sought via the internet. Still, there is a paucity of recen
In this paper, a factor-augmented version of the New Keynesian Phillips curve (NKPC) is assessed using a data set comprised of a large panel of European Union (EU) member countries. The factor-augmentation is natural given that country-level inflation rates are highly co-moving. The presence of unattended common factors is important because it raises the issue of omitted variables bias, as the rea
Diversification of forest industry activites into transport fuels is important for Swedish climate and energy policy goal achievement, and biofuel proponents also claim that it is important for Swedish forest industry competitiveness. There is significant ongoing research effort on biofuels for road transport and extensive experimentation on several technical platforms has been conducted. These di
This chapter is concerned with 3L1 acquisition (early trilingualism; i.e., the development of three languages during early childhood). This is a methodologically challenging and understudied topic, most typically focussing on children with two home languages that are both different from the language of the wider community. The available research on lexicon, syntax, and phonology shows that triling
