Search results

Type 2 diabetes (T2D) is the fastest growing non-infectious disease worldwide. Impaired insulin secretion from pancreatic beta-cells is a hallmark of T2D, but the mechanisms behind this defect are insufficiently characterized. Integrating multiple layers of biomedical information, such as different Omics, may allow more accurate understanding of complex diseases such as T2D. Our aim was to explore

Background: The purpose of this study is to determine the prevalence and morbidity of neck pain with or without cervical rhizopathy, upper extremity motor deficit and/or thoracolumbar pain in elderly men. Methods: We conducted a cross-sectional questionnaire study of 3,000 community-dwelling older men with a mean age of 75.4 ± 3.2 years (range 69–81) to determine if they had experienced neck pain

Study design: Cross-sectional and longitudinal. Objectives: To (i) describe health-related quality of life (HRQoL) and changes over 6 years in older adults aging with long-term spinal cord injury (SCI) and (ii) investigate how changes in HRQoL are associated with age, gender, and injury characteristics. Setting: Community in southern Sweden. Methods: From the initial 123 participants (years 2011–2

The research presented in this work represents reflections in the light of Julia Kristeva's philosophy concerning empirical data drawn from research describing the everyday life of people dependent on ventilators. It also presents a qualitative and narrative methodological approach from a person-centred perspective. Most research on home ventilator treatment is biomedical. There are a few publishe

Introduction: Atypical hemolytic uremic syndrome (aHUS) is a progressive and potentially life-threatening disease characterized by complement-mediated thrombotic microangiopathy. Patients with aHUS may experience fatigue, which can negatively impact their lives, but there is a knowledge gap regarding disease burden in these patients. Methods: In this longitudinal study, patients with aHUS from the

Diffuse ultrasonic wave measurements used in structural health monitoring applications can detect damage in concrete. However, the accuracy is very susceptible to environmental variations. In this study, a large concrete floor slab was monitored using diffuse wave fields that were generated by continuous-wave transmissions between ultrasonic transducers. The slab was monitored for several weeks wh

The present review covers a wide scope of occupational heat stress related issues. The problematics related to climate change have placed heat exposure on the agenda. As a result, the research on heat effects has increased in recent years and a considerable amount of new material has become available. The literature includes general and specific reviews that focus on various heat-related aspects i

The question whether students can be used as subjects in software engineering experiments is debated. In order to investigate the feasibility of using students as subjects, a study is conducted in the context of the Personal Software Process (PSP) in which the performance of freshmen students and graduate students are compared and also related to another study in an industrial setting. The hypothe

In the first part I discuss general problems of program-evaluation. In spite of a lot of problems concerning the practice of evaluation it is becoming more and more popular in programs with ambitions to develop social change. This development rise important issues concerning the relation between politics and science as well as about the methods, the value-criteria and the theories that are in use.

BACKGROUND: The act of swallowing after gastric pull-up esophagectomy has not been thoroughly investigated. The aim of this study was to evaluate deglutition in the esophageal remnant and in the gastric conduit in patients who have undergone this operation.METHODS: The residual radionuclide activity was measured 15 seconds after a swallow in the esophageal remnant and at intervals up to a maximum

The effect of mineral fertilization and its application pattern on microbial activity and the subsequent CO2 and CH4 emissions arising from soil organic matter (SOM) or added substrate remains unclear. We quantified the decomposition of 13C-labeled straw and the priming effect (PE) governed by the N and P fertilizer application pattern during a 100-day experiment in a flooded soil. Straw addition

Computer control is entering all facets of life from home electronics to production of different products and material. Many of the computers are embedded and thus ``hidden'' for the user. In many situations it is not necessary to know anything about computer control or real-time systems to implement a simple controller. There are, however, many situations where the result will be much better when

We estimated the biomass and growth of arbuscular mycorrhizal (AM) mycelium in sand dunes using signature fatty acids. Mesh bags and tubes, containing initially mycelium-free sand, were buried in the field near the roots of the dune grass Ammophila arenaria L. AM fungal mycelia were detected at a distance of about 8.5 cm from the roots after 68 days of growth by use of neutral lipid fatty acid (NL

During the last decade, identification of the genes involved in familial forms of Parkinson's disease (PD) has advanced our understanding of the mechanisms underlying the development of different aspects of PD. However the available animal models still remain as the main limiting factor for the development of neuroprotective therapies that can halt the progression of the disease, through which we

Disturbance of ecosystems is a major factor in regional carbon budgets, and it is believed to be partly responsible for the large inter-annual variability of the terrestrial part of the carbon balance. Forest fires have so far been considered as the most important disturbance but also other forms of disturbance such as insect outbreaks or wind-throw might contribute significantly to the largely un

We investigated how the legacy of warming and summer-drought affected microbial communities in five different replicated long-term (>10 years) field-experiments across Europe (EU-FP7 INCREASE infrastructure). To focus explicitly on legacy effects (i.e. indirect rather than direct effects of the environmental factors), we measured microbial variables under the same moisture and temperature in a bri

Previous studies using echocardiography in healthy subjects have reported conflicting data regarding the percentage of the stroke volume ( SV) of the left ventricle ( LV) resulting from longitudinal and radial function, respectively. Therefore, the aim was to quantify the percentage of SV explained by longitudinal atrioventricular plane displacement ( AVPD) in controls, athletes, and patients with