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Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of AZD0837 vs. vitamin K antagonists

Aims Oral anticoagulation with vitamin K antagonists (VKAs) for stroke prevention in atrial fibrillation (AF) is effective but has significant limitations. AZD0837, a new oral anticoagulant, is a prodrug converted to a selective and reversible direct thrombin inhibitor (AR-H067637). We report from a Phase II randomized, dose-guiding study (NCT00684307) to assess safety, tolerability, pharmacokinet

Input och output : ordföljd i svenska barns huvudsatser och bisatser

This thesis investigates the word order in the main and embedded clauses of four Swedish monolingual children, covering the age range 1;3–4;0. Using a generative framework, a quantitative and qualitative analysis focusing on the syntax of verb placement and complementizers is presented. Chapters 1 to 4 offer a background to the thesis. In chapter 1 the aims and the material are presented. Chapter

HIV och straffansvar - en kriminell sjukdom?

Denna uppsats syftar till att granska och diskutera kriminaliseringen av – och tillämpningen av straffrätten på – HIV-smittade personers sexuella kontakter där HIV-smitta överförs, eller riskerar att överföras, från en person till en annan. Upprätthållandet av ett straffhot avseende gärningar med grund i HIV är en kontroversiell fråga, i vart fall inom HIV/AIDS-arbetet på internationell nivå. SverThis paper aims to review and discuss the criminalization of – and the application of criminal law to – a HIV-infected person’s sexual contacts where HIV infection is transmitted, or may be transmitted from one person to another. Maintaining criminal sanctions for acts with a connection to HIV is a controversial issue, at least in HIV/AIDS work at an international level. Sweden, which is one of th

Deficiency of Peptidylglycine-alpha-amidating Monooxygenase, a Cause of Sarcopenic Diabetes Mellitus

Context: Peptidylglycine-α-amidating monooxygenase (PAM) is a critical enzyme in the endocrine system responsible for activation, by amidation, of bioactive peptides. Objective: To define the clinical phenotype of carriers of genetic mutations associated with impaired PAM-amidating activity (PAM-AMA). Design: We used genetic and phenotypic data from cohort studies: the Malmö Diet and Cancer (MDC;

Occurrence of the hermit beetle (Osmoderma eremita), in Sweden.

We have compiled data on the occurrence of a threatened beetle, Osmoderma eremita, in Sweden. The species inhabits tree hollows with wood mould. The data were compiled from field surveys conducted in 1993-2003, using pitfall traps at 401 localities and using wood mould sampling at 104 localities. We have also gone through published data and all larger Swedish museums and registered old records. O.

Perceived anxiety, depression, and sleeping problems in relation to psychotropic drug use among elderly in assisted-living facilities.

Objective: The aim of the present study was to investigate the perceived anxiety, depression, sleeping habits, and participation in social activities in relation to psychotropic drug use among elderly in assisted-living facilities and to identify factors of importance for the use of these drugs. Method: The study had a cross-sectional design and included 93 residents living in old-age homes or in

Intensive care medicine in Europe : Perspectives from the European Society of Anaesthesiology and Intensive Care

BACKGROUND Anaesthesiology represents a rapidly evolving medical specialty in global healthcare, currently covering advanced peri-operative, pre-hospital and in-hospital critical emergency management (CREM), intensive care medicine (ICM) and pain management. The aim of the European Society of Anaesthesiology and Intensive Care (ESAIC) is to develop and promote a coordinated interdisciplinary and m

Faculty of science guidelines lucris

Brevmall Postal address Box 118, 221 00 Lund Visiting address Astronomihuset, Sölvegatan 27 Telephone +46 46 222 48 54, +46 72 704 70 70 Email maria.ovesson@science.lu.se Website www.naturvetenskap.lu.se Dean Guidelines on making entries in the research information system LUCRIS In spring 2016, LU will implement a University-wide research information system, LUCRIS (Lund University Current Informa

https://www.science-library.lu.se/sites/science-library.lu.se/files/2021-06/faculty_of_science_guidelines_lucris.pdf - 2026-05-20

ASP computational-science

Allmän studieplan för forskarutbildning Page 1 of 10 Faculty Board SYLLABUS Reg. no U 2024/383 Date 12 June 2024 General syllabus for third-cycle studies in Computational Science, NABERV01 This syllabus was approved by the Faculty Board on 12 June 2024 and applies to doctoral students admitted from 2 September 2024. The syllabus is based on Chapter 6, Sections 1–11, 25–36, Chapter 7, Sections 34–4

https://www.science.lu.se/sites/science.lu.se/files/2024-10/ASP_computational-science.pdf - 2026-05-20

Multipark biobank access procedures

Microsoft Word - MultiPark Biobank Access Procedures_160502.docx MultiPark  Biobank  Access  Procedures     Overview   The  MultiPark  biobank  collection     The   MultiPark   biobank   sample   collection   (MPBC)   includes   three   major   parts;   information  from  MPBC  questionnaires,  blood  samples  and  registry  data.  At  entry,  blood   is   sampled   and   the   questionnaire   is

https://www.multipark.lu.se/sites/multipark.lu.se/files/multipark_biobank_access_procedures.pdf - 2026-05-20

Gisn23 english

Kursguide - Course Syllabus • • • • • • Details of approval The syllabus was approved by Study programmes board, Faculty of Science on 2013- 03-21 to be valid from 2013-03-22, autumn semester 2013. General Information The course is an elective course for second-cycle studies for a Degree of Master of Science (120 credits) in geographic information science. Language of instruction: English Learning

https://www.nateko.lu.se/sites/nateko.lu.se/files/gisn23_english.pdf - 2026-05-20

Conference consumption credit health and welfare

Microsoft Word - Conference_Consumoption, Credit, Health and Welfare.docx Conference, May 21-22: Consumption, Credit, Health and Welfare Welcome to a two-day Conference on Consumption, Credit, Health and Welfare. The Conference is organised as a collaboration between Pufendorf IAS, Lund University and SIFO, Norway. It is held in two separate parts of which the first,"Perspectives On The Credit Soc

https://www.pi.lu.se/sites/pi.lu.se/files/conference_consumption_credit_health_and_welfare.pdf - 2026-05-20

Sub-award agreement template simple

Sub-Award Agreement regarding the [name of grant] between Lund University , hereinafter referred to as “LU”, and [organisation] , hereinafter referred to as the “Sub-Awardee”; WHEREAS - [employee] has received a [name of grant] in accordance with Appendix 1 to carry out the research project “[name of project]” (the “Project”); and - the parties have agreed that the Sub-Awardee will perform certain

https://www.staff.lu.se/sites/staff.lu.se/files/sub-award_agreement_template_simple.docx - 2026-05-20

The pollination tragedy

The creation of floral resources for pollinators, such as flower strips, is seen as a relevant and needed intervention but comes with both cost and an opportunity for farmers. It may be worth it if, for example, pollinators are attracted to pollinator-dependent crops and deliver crop pollination. Unfortunately, since pollinators are mobile organisms, the spatial distribution of crop pollination re

Old-growth mixed beech-dominated forests continue accumulating carbon with advancing age

Old-growth forests uniquely support biodiversity while serving as some of the planet's most important carbon stocks. The influence of tree and stand age on carbon flux dynamics remains debated—an urgent question as climate-driven disturbances may reshape forest age structures and in situ carbon storage. To clarify these relationships in Fagus sylvatica , systems, we examined a unique dataset of 3,

Selenoprotein P Deficiency Is Associated with Early Signs of Kidney Disease and Hospitalization Risk in Heart Failure

Selenium (Se), an essential trace element, is linked to poor prognosis in heart failure (HF) and kidney disease. Se deficiency (serum Se < 70 μg/L) has been associated with increased cardiovascular mortality. Selenoprotein P (SELENOP), the main Se transporter, reflects bioavailable Se. Selective glomerular hypofiltration syndrome (SGHS), defined by a cystatin C-based eGFR < 0.7 of creatinine-based

Prostate Cancer Foundation Screening Guidelines for Black Men in the United States

BACKGROUND In the United States, Black men are at highest risk for being diagnosed with and dying from prostate cancer. Given this disparity, we examined relevant data to establish clinical prostate-specific antigen (PSA) screening guidelines for Black men in the United States. METHODS A comprehensive literature search identified 1848 unique publications for screening. Of those screened, 287 studi