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Inhibition of oxidative metabolism is often found to decrease contractility of systemic vascular smooth muscle, but not to reduce global [Ca(2+)](i). In the present study, we probe the hypothesis that it is associated with an altered pattern of intracellular Ca(2+) oscillations (waves) influencing force development. In the rat tail artery, mitochondrial inhibitors (rotenone, antimycin A, and cyani
Short-chain fatty acids (SCFAs) have attracted much attention recently because of their positive physiological effects. In this work, a rapid and reliable gas chromatographic method for determination of eight SCFAs, in colonic and faecal samples from rats and humans has been developed and validated. The methodology involves extraction of the SCFAs in water before a direct injection procedure on a
Objective:To determine whether the combined intervention of 50 000 IU vitamin A administered together with Bacille Calmette-Guerin (BCG) vaccination at birth was associated with adverse events, in particular bulging fontanels and adverse reactions to BCG.Subjects/Methods:From an ongoing trial, 2145 infants randomized to 50 000 IU vitamin A or placebo with BCG vaccination were recruited. Adverse ev
Organic substrates for pelagic bacteria are derived from dissolved organic carbon (DOC) in the water column. DOC is a heterogeneous mixture of molecules, some of which are imported from the watershed (allochthonous DOC) and others that are produced by autotrophs within the system (autochthonous DOC). We examined the importance of autochthonous versus allochthonous DOC in supporting the growth of p
Objective. Selective leukocyte apheresis is a new type of non-pharmacological treatment for patients with active ulcerative colitis and Crohn's disease. Preliminary data have indicated that this type of therapy is safe and efficacious, and large sham-controlled studies are currently in progress. In Scandinavia, a substantial number of patients with chronic inflammatory bowel disease have already r
TB PNA FISH is a new fluorescence in situ hybridization (FISH) method using peptide nucleic acid (PNA) probes for differentiation between species of the Mycobacterium tuberculosis complex (MTC) and nontuberculous mycobacteria (NTM) in acid-fast bacillus-positive (AFB+) cultures is described. The test is based on fluorescein-labelled PNA probes that target the rRNA of MTC or NTM species applied to
Med sin ökade tillgänglighet på den kommersiella marknaden har eye-tracking blivit ett allmänt tillgängligt system för att analysera ögonrörelser. Detta har öppnat upp för nya möjligheter för utvärdering av usability inom humancomputer interaction, som tidigare har varit dyrt, tidskrävande och ofta utfört baserat på dåligt dokumenterade standarder och mål. Tidigare forskning har visat att eye-tracWith its increased availability on the commercial market, eye-tracking has become a widely accessible system for analysing eye-movements. This has opened up new possibilities in evaluation of usability in human-computer interaction, which has had a history of being expensive, time-consuming and often performed based on poorly documented standards and objectives. Previous research has indicated the
This essay concerns the complementation of the English emotive verbs like, love, hate and prefer. In English, gerund-participial and infinitival complements often receive semi-synonymous semantic interpretations when complementing emotive verbs. All the while, both complement types supposedly convey separate semantic interpretations, resulting in that they commonly appear in contexts expressing ha
Studien ämnade att undersöka hur väl personlighet respektive könsidentifiering, var för sig respektive tillsammans, kan predicera ideologisk orientering. För att undersöka detta användes personlighetstestet HEXACO och könsidentifieringstestet BSRI. Syftet med uppsatsen var att öka väljarförståelsen. Studien utgick ifrån ett bekvämlighetsurval (N=272), med 171 kvinnor och 101 män. Samtliga var svenThis aim of this thesis was to examine how well personality and gender-identification, by themselves and combined, were able to predict ideological orientation. This through the personality test HEXACO and gender-identification test BSRI. The purpose of the study was to help improve the understanding of Swedish voters. The sample was a convenience sample (N=272), with 171 women and 101 men, all Sw
Studiens syfte var att undersöka om det fanns ett samband mellan anställningsotrygghet och upplevt psykiska välmående med det sociala samspelet mellan kollegor som en medierande effekt. Detta undersöktes genom en webbaserad enkät, där upplevt psykiskt välmående, anställningsotrygghet och det sociala samspelet mättes med konstruktestade formulär. Deltagarna (N=87) var anställda i livsmedelsbutiker The purpose of the study was to examine if there is a covariance between job insecurity and the experienced mental well-being with the factor social interaction between co-workers as a mediating effect. This was studied through a web survey where experienced mental well-being, social interaction and job insecurity was measured with construct validated surveys. The participants (N=87) were employee
This study is written in collaboration with the Swedish Police in Landskrona. The study aimed to identify reported assaults in public places in Landskrona during the period of 2016-2019. The study consists of statistical data analysis of secondary data and was carried out using the statistical program SPSS. The empirical data consisted of register data from the Police's internal reporting syst
Background In ST-elevation myocardial infarction (STEMI), distal embolization of thrombus material often precludes restoration of normal coronary artery flow. Small-scaled studies have demonstrated that intracoronary thrombus aspiration improves flow and myocardial perfusion, but only one larger randomized single-center study has suggested a survival benefit. Thrombus aspiration is widely used in
Acute lymphoblastic leukemia (ALL) is the major pediatric cancer diagnosed in economically developed countries with B-cell precursor (BCP)-ALL, accounting for approximately 70% of ALL. Recent genome-wide association studies (GWAS) have provided the first unambiguous evidence for common inherited susceptibility to BCP-ALL, identifying susceptibility loci at 7p12.2, 9p21.3, 10q21.2, and 14q11.2. To
BACKGROUND: The need for completion axillary lymph node dissection (ALND) in breast cancer patients with micrometastases in the sentinel nodes (SNs) is controversial. The aim of this retrospective observational study is to determine if the method of detection of early breast cancer is predictive for additional positive nodes in patients with micrometastases in the SNs. METHODS: Between 2001 and 20
