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The cycloruthenation of 2-phenylimidazole (phim) by [Ru(6-C6H6)(-Cl)Cl]2 in acetonitrile in the presence of NaOH has been carried out. The unstable intermediate [Ru(phim)(MeCN)4]PF6 formed has been converted into the complexes [Ru(phim)(4,4′-Me2bpy)(MeCN)2]PF6 (2) and [Ru(phim)(LL)2]PF6 (3, LL=phen (a), bpy, 4,4′-Me2bpy), which were characterized by the mass-spectrometry, 1H-NMR spectroscopy, UV–v
Treatment with adrenocorticotrophic hormone (ACTH) has a well-documented cholesterol-lowering effect. Increased uptake of low-density lipoprotein (LDL) by HepG2 cells in response to incubation with ACTH has been demonstrated but the precise cholesterol-lowering mechanism has resisted elucidation. Since apolipoproteins are important determinants of lipoprotein metabolism, we sought to extend the kn
The Fra a I allergen in strawberry (Fragaria ananassa) is homologous to the major birch pollen allergen Bet v 1, which has numerous isoforms differing in terms of amino acid sequence and immunological impact. To map the extent of sequence differences in the Fra a I allergen, PCR cloning and sequencing was applied. Several genomic sequences of Fra a 1, with a length of either 584, 591 or 594 nucleo
Superporous agarose beads were used as a support for hydrophobic interaction chromatography. These beads have large connecting flow pores in addition to their normal diffusion pores. The flow pores, which are approximately one fifth of the overall diameter of the superporous agarose beads, were earlier shown to give the beads improved mass transfer properties relative to homogeneous agarose beads
Poly(styrene-graft-ethylene oxide), having alkyl chains (C-12 or C-18) on the polystyrene main chain or on the poly(ethylene oxide) (PEO) side chains, were synthesized. The main chain was alkylated by first ionizing amide groups in a styrene/acrylamide copolymer with tert-butoxide, and then using the amide anions as sites for reactions with 1-bromoalkanes. An excess of amide anions was used in the
Background & Aims: Human milk is believed to contain biological factors involved in the regulation of newborn growth, including brain development. Recently, it has also been shown to contain the calcium-binding S100B protein, regarded as a neurotrophic factor. The present study investigates the concentrations of this protein in colostrum, human milk at different levels of maturation and in mil
The Multi-plume Aerosol dynamics and Transport (MAT) model has been developed to study the dynamics of the particle size distribution in urban environments. The MAT model uses a novel multi-plume scheme for vertical dispersion and routines of the aerodynamics models AERO3. It treats the processes: emission from a near ground source, dilution with background air, deposition, coagulation and condens
Increased nitrogen leaching from forest soils is a potential environmental problem in areas with high nitrogen deposition. In Sweden nitrogen is strongly retained in the forests, and high nitrogen leaching is not common from growing forests. However, soil water measurements on clearcuts along a deposition gradient in Sweden showed a positive correlation between increased concentration of inorganic
PURPOSE: The development of tumor-specific markers to select targeted therapies and to assess clinical outcome remains a significant area of unmet need. We evaluated the association of baseline circulating tumor cell (CTC) number with clinical characteristics and survival in patients with castrate metastatic disease considered for different hormonal and cytotoxic therapies. EXPERIMENTAL DESIGN: CT
Popular Abstract in Swedish Oberoende av om det är i ett samhälle, datornätverk eller organen i en mänsklig kropp, så är behovet av kommunikation stort i en komplex miljö. Eftersom den komplicerade människokroppen är beroende av kommunikation för att reglera funktioner, skickas otaliga mängder signaler oavbrutet. För att signalerna skall vara meningsfulla så måste de kunna tas emot och behandlas.
This symposium presents two tracks, one practical and one more theoretical, divided in ten topics, and presented in three parallel sessions. Two new topics are introduced; “Historical Buildings” and “Challenges for the future”. The intention of adding Historical Buildings is to gather people with different backgrounds, for example Building Physicists, Building antiquarians, Building Biologists, Ar
The care of demented patients requires clear communication during care procedures. Earlier studies have shown that nurses were often vague in their verbal communication and unpublished observations indicated that in some cases demented patients continued to be verbally active after the nurses had left. This study aimed at exploring further the initiating and terminating phases of verbal interactio
Fe 0 fluorescence by PAR has been investigated in eight symbiotic starshaving a wide range in temperature of the hot component and orbitalperiod. The data used are spectra obtained from the IUE archive. Allpumping lines investigated in this work are in the short wavelengthregion of IUE (1200-2000 Å), except for He 0 λ 1084.942 andO 0 λ 1032.041. The resulting Fe 0 fluorescence lines are mainlyin t
Prostate-specific antigen (PSA) and human prostatic glandular kallikrein (hK2) have 79% identity with the primary structure. When we used recombinant hK2 protein, only 7 of 23 monoclonal anti-PSA IgGs (monoclonal antibodies, MAbs) cross-reacted with hK2, which enabled us to design a novel immunofluorometric MAb-MAb assay for the specific detection of hK2. In the first incubation, an excess of MAb
Gas turbines emissions, NOX in particular, have negative impact on the environment. To limit the emissions gas turbine burners are constantly improved. In this work, a fourth generation SIT (Siemens Industrial Turbomachinery) burner is studied to gain information about the formation of NOX emissions. The gas mixtures for the full burner are limited to natural gas with different nitrogen dilutions.
Aim: The Driving to Learn project focused on people with profound cognitive disabilities and their possible achievements from practicing joystick-use in a powered wheelchair. The aim of this study within the project was to statistically analyse the participants' outcomes, and to explore factors, in terms of participant and training characteristics, associated with a favourable outcome of training
Popular Abstract in Swedish I avhandlingen studeras plasminogenaktiverings-systemets (PA-systemets) komponenter i livmoderslemhinnan. PA-systemet reglerar omvandlingen av plasminogen till plasmin. Plasminogen är ett inaktivt enzym som finns överallt i kroppsvätskor samt i kroppens olika organ. Aktiveringen katalyseras av aktivatorer, antingen urokinase plasminogen activator (uPA) eller tissue plasThe release of urokinase plasminogen activator (uPA) from endometrial stromal cells decreased after progesterone stimulation, due to upregulation of PA inhibitor 1 (PAI-1) and uPA receptor (uPAR). Subsequently, the uPA:PAI-1 complex was internalized and degraded via uPAR. Predecidual cells in the late secretory phase expressed PAI-1 and uPAR, supporting a specific role for predecidual cells in the
