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Left atrial appendage outflow velocity index is superior to conventional criteria for prediction of maintenance of sinus rhythm after cardioversion. An echocardiographic study in patients with atrial fibrillation of a few months' duration

OBJECTIVE: To investigate whether left atrial appendage outflow velocity alone or in relation to left atrial diameter is a superior predictor of sinus rhythm maintenance after cardioversion compared with traditional clinical or echocardiography parameters. DESIGN: Sixty-two patients with their first episode of atrial fibrillation were examined using echocardiography before DC-cardioversion. At one

Dietary intakes and plasma concentrations of carotenoid's and tocopherols in relation to glucose metabolism in subjects at high risk of type 2 diabetes: the Botnia Dietary Study

Background: The role of antioxidants in the pathogenesis of type 2 diabetes is uncertain. Objective: We evaluated cross-sectional relations of dietary intakes and plasma concentrations of antioxidants with glucose metabolism in a high-risk population. Design: The subjects, were 81 male and 101 female first- and second-degree, nondiabetic relatives of patients with type 2 diabetes. Antioxidant inta

A 2-year prospective study of patient-relevant outcomes in patients operated on for knee osteoarthritis with tibial osteotomy

Background: Tibial osteotomy is a treatment for younger and/or physically active patients suffering from uni-compartmental knee osteoarthritis. The open wedge osteotomy by the hemicallotasis technique includes the use of external fixation. The use of external fixation has several advantages, as early mobilization and the opportunity for optimal correction. However, the hemicallotasis technique has

Social inequalities in health- do they diminish with age? Revisiting the question in Sweden 1999.

BACKGROUND: Individuals with low income have poorer health and should, therefore, have higher health expenditure than people with high income particularly in countries with a universal health care system. However, it has been discussed if social inequities in health diminish with age and we, hence, aimed to analyse this question. METHODS: We performed an age stratified cross-sectional analysis usi

Xenoestrogenic activity in blood of European and Inuit populations

BACKGROUND: Human exposure to persistent organic pollutants (POPs) is ubiquitous and found in all individuals. Studies have documented endocrine disrupting effects and impact on reproduction. The aim of the present study was to compare the level of xenoestrogenic activity in serum of groups with varying POP exposure, and to evaluate correlations to the POP biomarkers, 2,2',4,4',5,5'-hexachlorobiph

Liver dendritic cells present bacterial antigens and produce cytokines upon Salmonella encounter.

The capacity of murine liver dendritic cells (DC) to present bacterial Ags and produce cytokines after encounter with Salmonella was studied. Freshly isolated, nonparenchymal liver CD11c(+) cells had heterogeneous expression of MHC class II and CD11b and a low level of CD40 and CD86 expression. Characterization of liver DC subsets revealed that CD8alpha(-)CD4(-) double negative cells constituted t

Overactive bladder: prevalence, risk factors and relation to stress incontinence in middle-aged women.

Objective To investigate the prevalence of and factors associated with overactive bladder in middle-aged women. Design Cross sectional population-based study. Setting Southern Sweden and the Women's Health in the Lund Area study (WHILA 1995-2000) where 6917 (64% of the invited) women, 50-59 years old in 1995, participated. Population From the WHILA study, 1500 women reporting troublesome urinar

Purification and properties of the cGMP-inhibited cAMP phosphodiesterase from bovine aortic smooth muscle

Pure cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) in micrograms quantities was isolated from bovine aortic smooth muscle after more than 5000-fold purification using DEAE ion-exchange and affinity chromatography with a derivative of the specific cGI-PDE inhibitor cilostamide conjugated as a ligand to aminoethyl agarose (CIT-agarose). The cGI-PDE, which constituted about half of the high affinit

Survival rate 28 days after hospital admission with first myocardial infarction. Inverse relationship with socio-economic circumstances.

Objective. To study to what extent geographical differences of the mortality from ischaemic heart disease (IHD) can be accounted for by the 28-day case fatality rate (CFR) following first hospital admittance for acute myocardial infarction (MI) and whether the geographical pattern of survival has any relationship with socio-economic circumstances. Design. Register-based surveillance study. Setting

Bladder exstrophy : Clinical and experimental aspects

Popular Abstract in Swedish Blåsexstrofi är en ovanlig och mångfasetterad missbildning. I hela Sverige föds cirka tre barn om året med blåsexstrofi. Bukvägg och urinblåsa är öppna nedanför naveln, så att man ser blåsans insida samt rinnande urin. Flickorna har en delad clitoris, framflyttad och trång slidöppning samt framflyttad ändtarmsöppning. Pojkarna har en kort, öppen penis, som ligger uppfäl

Body Protein and its Change in Patients During Anti-Tumor Treatment

Popular Abstract in Swedish Förändring av kroppsprotein hos cancerpatienter under behandling Bakgrund Det är välkänt att patienter med cancer ofta drabbas av nedsatt aptit, viktminskning, orkeslöshet och ämnesomsättningsrubbningar under sin sjukdom. Denna samlade symptombild kallas kakexi. Detta tillstånd minskar toleransen för olika behandlingar, som cytostatika- och strålbehandling, försämrar The purpose of this study was to investigate how total body protein and its fraction of body weight (body protein fraction) change in cancer patients during different anti-tumor treatments, and to see if these changes have any clinical significance in the form of prognostic value or correlation with disease course and tumor response. In 84 patients, 28 with lung cancer, 24 with gastrointestinal t

Cygnet or ugly duckling – what makes the difference? A tale of heat-pump market developments in Sweden

Who can pick a winner? Since 1974, various types of targeted support have at different times been directed at the development of the heat pump market in Sweden – which in the following decades oscillated violently between soaring sales and collapse. Eventually, however, small heat pumps for space heating of residential buildings have in recent years securely established themselves as a mature and

Potent inhibitors of uropathogenic E. coli papG adhesins; Synthesis, conformational studies and biological evaluation of galabiose derivatives and synthesis of glycosphingolipid analogues

The importance of carbohydrates in biological systems has become evident during the last fifty years. It is well known that pathogenic bacteria and viruses attach to glycoconjugates present at mammalian cell surfaces, and that this attachment is a prerequisite for the later stages of infection. Obviously, this interaction is interesting as a target for the development of novel ways to treat bacter

Aspects on the Regio and Stereo Selectivity in the Hydrolsilylation of 1,3-Dienes

Popular Abstract in Swedish Hydrosilyleringsreaktionen är formellt en addition av en hydrosilan till ett omättat system. Reaktionen är oftast katalyserad av en övergångsmetall, och i denna process är det möjligt att påverka på vilket sätt additionen sker. Denna avhandling är en sammanfattning av fyra artiklar som behandlar regio-, stereo- och kemoselektivitet vid addition av hydrosilaner till konjThis thesis is a summary of four papers concerning various aspects on the transition metal catalysed hydrosilylation of 1,3-dienes. The hydrosilylation reaction is formally an addition of a hydrosilane to an unsaturated system and depending on the reaction conditions, control of stereo-, regio-, and chemo-selectivity can be achieved. Optically active heterobidentate P,N ligands were synthesised f

Resonant Tunneling in Laterally Confined Quantum Structures

In the thesis, three-dimensionally confined resonant tunneling structures were studied experimentally. Two approaches were used for obtaining quantum confinement: gate-defined lateral constriction of double barrier structures, and epitaxial growth of self-assembled quantum dots. In addition, the thesis deals with the basic development of large-area double barrier resonant tunneling diodes, as a st

Thermo-economic evaluation of bio-ethanol humidification EvGT cycle

The evaporative gas turbine pilot plant (EvGT) has been in operation at Lund Institute of Technology in Sweden since 1997. This article presents the latest development in the evaporative technology, the evaporation of bio-ethanol in a gas turbine power plant as a means to reduce the emission of greenhouse gases. Bio-ethanol is produced from a feedstock consisting of corn-stover, and the bio-ethano

Concentrated DNA-amphiphiles Structure, Hydration, and Dynamics

Popular Abstract in Swedish DNA är en molekyl som finns närvarande i stan alla celler och den innehåller den genetiska koden för utvecklingen av alla former av liv. Molekylen är väldigt tunn (2 nanometer i diameter) och lång - mänskligt DNA skulle vara ca en meter lång i utsträckt tillstånd. Inuti cellerna antar DNA en superkompakt struktur för att få plats inuti en cellkärna med bara ca 10 mikromThe structure, hydration, and dynamics of concentrated DNA-amphiphile complexes were investigated by small-angle X-ray diffraction, sorption calorimetry, and nuclear magnetic resonance. A concentrated, electroneutral, DNA-amphiphile complex can be formed by mixing charge-stoichiometric solutions. The effect is a strong association of DNA with the oppositely charged amphiphile resulting in the form