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T cell-exosomer som biomarkör vid Typ 1-Diabetes Typ 1-diabetes (T1D) är en autoimmun sjukdom, där kroppens T-celler (immunceller) angriper bukspottskörtelns insulinproducerande betaceller. Insulin är ett viktigt hormon, som reglerar blodsockerhalten i kroppen. Destruktion av betacellerna leder till nedsatt insulinproduktion och därmed höga blodsockerhalter, som följaktligen leder till andra kompType 1 diabetes, also known as juvenile diabetes or insulin-dependent diabetes, is a growing and serious health problem worldwide with highest incidence in developed countries and among children. It is a T cell-mediated autoimmune disease, characterized by destruction of β-cells of the pancreatic islets of Langerhans, resulting in deficient insulin secretion and hyperglycemia. The cause of the dis

Förhöjda temperaturer på höga breddgrader kan förändra koldynamiken i hela Arktis. Modellerade CO2 simuleringar visar att under nuvarande klimatförhållanden utgör Arktis en netto kolsänka, fast den stora utsträckningen samt fina geografiska heterogenitet lyfter upp osäkerhet kring dess status som CO2 sänka/källa i regionen. Förståelsen för arktiska koldioxidflödekan förbättras genom integrering avIncreased temperatures in high latitudes may alter the carbon dynamics throughout the Arctic. Modelled CO2 simulations show that current climate conditions constitute the Arctic a net carbon sink, though the large extent and fine landscape heterogeneity raise an uncertainty about the carbon sink/source status of the region. The understanding of Arctic CO2 fluxes can be improved through integration

Today, bioethanol is predominately produced with conventional feedstock that may not be desired for ethanol production due to their primary food and animal feed value. Therefore, lignocellulosic biomass, a relatively cheap and non-food competitive biomass has received attention. However, the complexity of lignocellulosic biomass poses challenges to developing a large-scale production process compe

Det har nog inte undgått någon att det är bråttom att minska på utsläppen av växthusgaser samt nyttjandet av jordens naturresurser. För att detta ska bli möjligt behöver vi ta vara på de resurser som redan finns i så stor utsträckning som möjligt, innan vi väljer att kassera dem. Restauranger är en verksamhet där det uppstår stora mängder avfall och där det kan vara svårt att veta hur man ska gå t

Att bygga nytt för klimatet Med en ökande befolkning ökar även behovet av bostäder, kontor samt skolor och förskolor. En ny byggnad ger upphov till växthusgasutsläpp under hela sin livscykel. Tidigare har fokus legat på byggnadens driftsskede, men allt eftersom byggnaderna blir energisnålare flyttas fokuset över till byggnadens byggprocess. Byggbranschen står för en femtedel av Sveriges växthusgasAs the population increases, so does the need for residential buildings, offices, schools and preschools. The construction industry accounts for about 20% of Sweden’s greenhouse gas emissions. While buildings become more energy-efficient the focus is shifted from the operational phase to the construction phase. The law on climate declaration is a Swedish law, which holds developers responsible for

This research analyses the presence of political personalisation and its role in establishing performed authenticity in political content on TikTok. Despite TikTok being a platform created for entertainment purposes, TikTok has come to play a significant role in political discourse and engagement with politicians Employing a qualitative approach to Multimodal Critical Discourse Analysis, this rese

Swedish students obtaining student financial aid from Centrala Studiestödsnämnden (CSN) face an income ceiling of how much they can earn per half a calendar year before their aid is lowered according to a matrix. The thesis investigates how CSN’s income ceiling impacts students. It is important to examine it as it is a hot topic both in the public debate and among politicians. The analysis of the

Inom större byggnader används ofta installationsschakt, vilket är en brandteknisk avskild vertikal förbindelse mellan våningsplan för kanaler av olika media. Genom att använda ett sådant schakt går det att undvika isolering, brand-/brandgasspjäll och liknande åtgärder när rör- och kanalgenomföringar går igenom brandceller. Ofta är schakten avsedda för flera kanaler, då besparingar i form av isolerWithin larger buildings, shafts for installations are often used as a hub for air ducts and pipes for other medias across different floors of the buildings. The walls of such shafts are currently required, for most cases, to have the same fire protection rating as an ordinary wall. Forshafts which are performed with non-combustible materials, or done with extra fire protection within the shaft, th

As society becomes more ecologically conscious there is a push toward the use of materials with a smaller environmental burden, one of these materials is glulam (GLT), which has gained a lot of traction in recent years not only for ecological reasons but for its ease in manufacture, transport, noise dampening, etc. The focus of this project was to evaluate the influence of different joint configu

Inflammation Profiling in Chemotherapy One of the methods used for treating leukemia and various types of cancer is chemotherapy that is spread over multiple cycles of treatment. The chemotherapy is toxic for the blood system and severely decreased cellular output and may leave the bone marrow (BM) impaired leading to myelosuppression. Myelosuppression is a state where the BM have problems to re

Varje år sker det tusentals olyckor i trafiken i Sverige till följd av det stora transportbehovet i samhället. Transportstyrelsen har ett mål, Nollvisionen, som innebär att ingen ska dödas eller skadas allvarligt i trafiken. För att nå målet är en åtgärd att hastigheten sänks där gång- och cykeltrafik behöver interagera med motorfordon. Det kan man göra i form av sidoförskjutningar, avsmalning av Every year, thousands of traffic accidents occur in Sweden as a result of the transportation need in society. The Swedish Transport Agency has a goal, Vision Zero, which means that no one should die or be severely injured in traffic. To reach the goal one measure is to reduce the speed where pedestrians and cyclists need to interact with motor vehicles. This can be done by chicanes, narrowing of t

Microalgae belong to the group of the oldest microorganisms that can grow in both fresh and marine water. Microalgal biomass is a rich source of vitamins, lipids, pigments and essential amino acids. Microalgal biomass can be used without cracking and fractionation or it can be cracked, fractionated and purified to get particular components like vitamins, pigments, omega-3 oils and proteins. But du

Language is a social act and the fact that social communities create new or change existing words that are known in daily standard language, can make the lexicon difficult to comprehend for the ones not involved. The communication that belong to a specific social group can be classified as a jargon, and in this present study we look at gaming language as an example of how social communities’ lexic

As a country with a high proportion of population and land area in the world, China is in a stage of changing its economic development direction, from the previous extensive economic growth to the intensive economic growth. At the same time, due to the limited total amount of resources and limited environmental bearing capacity on the earth, certain constraints are found in terms of amount and str

This dissertation investigates the function of the sea in contemporary British and Irish literature, focusing on the following three novels: Dermot Bolger’s Temptation (2000), John Banville’s The Sea (2005), and Ian McEwan’s On Chesil Beach (2007). The analysis is divided into two main parts, where the sea is considered in its roles as a setting and as a symbol. The former section starts with a su