Filetype
Extracellular vesicles (EVs) are membrane enclosed biological nanoparticles released by cells. In the past two decades, EVs have gained a lot of attention due to their role in numerous biological processes. However, their small nature complicates isolating them from biological fluids with cumbersome techniques, such as ultracentrifugation. Acoustic trapping is a technique that uses ultrasonic stan
Recent studies on Alzheimer's disease (AD) suggest that tau proteins spread through the brain following neuronal connections. Several mechanisms could be involved in this process: spreading between brain regions that interact strongly (functional connectivity); through the pattern of anatomical connections (structural connectivity); or simple diffusion. Using magnetoencephalography (MEG), we inves
Background: Following exposure to traumatic stress, women are twice as likely as men to develop mood disorders. Yet, individual responses to such stress vary, with some people developing stress-induced psychopathologies while others exhibit resilience. The factors influencing sex-related disparities in affective disorders as well as variations in resilience remain unclear; however, emerging eviden
Rodent models are important research tools for studying the pathophysiology of traumatic brain injury (TBI) and developing new therapeutic interventions for this devastating neurological disorder. However, the failure rate for the translation of drugs from animal testing to human treatments for TBI is 100%. While there are several potential explanations for this, previous clinical trials have reli
Land use change from agricultural intensification has been highlighted as one of the major drivers of global declines in insects, reducing species diversity and abundance and shifting community composition towards generalist species. However, it remains a challenge to determine how land use change impacts the genetic diversity of species and populations even if this diversity is vital to their lon
Popular Abstract in Swedish Enbart i Sverige drabbas tusentals personer årligen, kvinnor som män, av plötsligt cirkulationsbortfall (akut ischemi) i ett ben till följd av blodpropp i en artär. Tillståndet är akut och innebär ett direkt hot mot såväl liv som lem. Personer som drabbas är ofta äldre, och de har ofta många andra sjukdomar med sig i bagaget. För att rädda benet, och patienten, krävs aBackground: Acute ischemia of the lower limb is a vascular emergency associated with amputation and death. Patients suffering from acute limb ischemia are usually elderly, and multiple comorbidities are often present. Intra-arterial thrombolysis is, perhaps, the most important minimal-invasive treatment option available today. Although uncontrolled hemorrhage is a dreaded complication, it is consi
Most deterioration processes in cement based materials are closely related to moisture sorption and moisture transport properties. Therefore, it is important to study these properties, both theoretically and practically. This work is an experimental investigation in this field. Nowadays, the cement industry produces cements with increasing amounts of supplementary cementitious materials (SCMs) to
The joint Swedish-Russian “Tundra Ecology-94” expedition during 1994 used the large Russian ice-breaking research vessel R/V Akademik Fedorov a platform and went along a coastline of 3500 km-from the Kola Peninsula 10°E to Kolyuchinskaya Bay 173°E. Radioactivity in air, seawater and sediment was explored at various locations along the route. The average of 7Be activity concentration in air over th
In this study, we compare annual fluxes of methane (CH4), nitrous oxide (N2O) and soil respiratory carbon dioxide (CO2) measured at nine European peatlands (n = 4) and shrublands (n = 5). The sites range from northern Sweden to Spain, covering a span in mean annual air temperature from 0 to 16 degrees C, and in annual precipitation from 300 to 1300 mm yr(-1). The effects of climate change, includi
Det finns en stor potential för ett ökat utnyttjande av biomassa för energiändamål i Sverige. En ökad användning av biomassa skulle kunna bidra till att minska utsläppen av koldioxid från förbränning av fossila bränslen, minska beroendet av importerade fossila energibärare samt påverka den regionala och lokala miljösituationen såväl positivt som negativt. Föreliggande studie behandlar framför alltThere is a large potential for increasing the use of biomass for energy purposes in Sweden. Increasing the use of biomass can reduce emissions of carbon dioxide (CO2) from fossil-fuel combustion and dependence on imported fossil fuels. Furthermore, increased biomass use will affect emissions of other air pollutants than carbon dioxide as well as environmental impacts from land use. The study deals
Background: Blood lipid levels including low-density lipoprotein cholesterol ( LDL-C), high-density lipoprotein cholesterol ( HDL-C), and triglycerides ( TG) are highly heritable. Genome-wide association is a promising approach to map genetic loci related to these heritable phenotypes. Methods: In 1087 Framingham Heart Study Offspring cohort participants ( mean age 47 years, 52% women), we conduct
Popular Abstract in Swedish Komplementsystemet är ett system bestående av cirka 35 proteiner i blodet och på cellytor, som ingår i kroppens medfödda immunförsvar. Det är ett mycket viktigt men också explosivt system, potentiellt skadligt för kroppens egna celler, som kräver strikt reglering. Denna avhandlings huvudaktör, C4b-bindande protein (C4BP), nedreglerar komplementsystemet. C4BP har en ovanThe subject of this thesis is plasma protein C4b-binding protein (C4BP). C4BP is an important regulator of the classical pathway of the complement system, a cascade-like system comprised of over 35 proteins, which partakes in the defence against micro-organisms and is involved of clearance of immune-complexes and apoptotic cells. C4BP contains two different types of subunits, seven identical alfa-
Most modern ultrafast lasers are based on mode-locked fiber or solid-state lasers and operate around the near infrared part of the electromagnetic spectrum. The widely spread CPA based Titanium Sapphire lasers can emit pulses centred around 800nm with durations down to 20 fs. However, for many ultrafast experiments light at different centre frequencies are required. In order to obtain other centre
Traditionellt anses vulkanoklastiska interbeds ha dålig reservoarpotential på grund av de vulkaniska komponenterna, som lätt kan omvandlas till olika lermineral. Publicerade arbeten från interbasaltiska sedimentära avlagringar i Faroe-Shetlands Basin tyder dock på annat. Denna studie syftar därför till att utvärdera porositets- och permeabilitetsegenskaper hos vulkanoklastiska interbeds från FaroeTraditionally, volcaniclastic interbeds have been considered to have poor reservoir potential due to their volcanic components readily altering to various clay minerals, but published discoveries within lava successions in the Faroe-Shetland Basin may challenge this dogma. This study therefore, evaluates porosities and permeabilities for volcaniclastic interbeds from the Faroe Islands Basalt Group
Abstract: The zooplankton community of The Area of Multiple Use Hawaii (AUMH), South Pacific Coast of Guatemala mangrove channel ecosystem was studied in the dry season between February and March 2011. Zooplankton samples were taken during two lunar cycles, four tidal cycles (flood, high water (HW), ebb, low water (LW)), at four different sites. For each sampling occasion, salinity, pH, dissolved
Abstract Estuaries and salt marshes are important wetlands used by waterbirds during winter and migration. However, many salt-marshes have been transformed into salinas, which currently function as high-tide roosts. Since traditional salt production is no longer profitable, many salinas have been abandoned or converted into aquaculture potentially becoming less attractive to waders. In this study
BACKGROUND: Following the economic crisis in Greece in 2010, the country's ongoing austerity measures include a substantial contraction of health-care expenditure, with reports of subsequent negative health consequences. A comprehensive evaluation of mortality and morbidity is required to understand the current challenges of public health in Greece.METHODS: We used the results of the Global Burden
Uppsatsen behandlar selektiv distribution av luxuösa produkter samt hur marknadsrättsliga regler påverkar möjligheten att upprätthålla sådana system. Lyxprodukter definieras i rättspraxis som högkvalitativa produkter med ett relativt högt pris som marknadsförs under prestigefyllda varumärken. Eftersom karaktären av lyx utgör den främsta konkurrensfördelen vid distribution av denna typ av produkter
Uppsatsen behandlar budpliktsinstitutet i Sverige samt i några andra utvalda länder. Fokus ligger på vilka subjekt som kan drabbas av sanktion, samt vilka typer av sanktioner som finns att tillgå vid ett brott mot sagda budplikt. Institutet har kommit att bli ett av de mer omdiskuterade reglerna på värdepappersmarknaden då det råder osäkerhet om huruvida regeln verkligen passar det svenska företag
