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Changes in incidence and prevalence of vertebral fractures during 30 years

The age and sex-specific incidence and prevalence of vertebral compression fractures were compared between the 1950s and 1980s in an urban population. In women over 80 years of age the incidence of symptomatic vertebral fractures has increased approximately four times; in elderly men even more. Mainly, low-energy trauma has caused these fractures. Thus, one clinical manifestation of osteoporosis--

Midline carcinoma with t(15;19) and BRD4-NUT fusion oncogene in a 30-year-old female with response to docetaxel and radiotherapy

Background: Poorly differentiated midline carcinoma with a translocation between chromosomes 15 and 19, i.e. t(15; 19), has been recognized as a distinct clinical entity for over a decade. This tumor affects young individuals, shows a rapidly fatal clinical course despite intensive therapy. The t( 15; 19) results in the fusion oncogene BRD4-NUT. Information concerning treatment of this rare disord

Patch testing with 2.0% (0.60 mg/cm(2) ) formaldehyde instead of 1.0% (0.30 mg/cm(2) ) detects significantly more contact allergy.

Background.The currently used patch test concentration for formaldehyde is 1.0% (wt/vol) in water. However, clinical experience and previous studies suggest that 1.0% might be insufficient for detecting an optimized number of clinically relevant cases of contact allergy to formaldehyde. Objectives.To validate earlier patch test results for comparison of 1% (wt/vol) and 2% (wt/vol) formaldehyde in

Prevalence of dementia subtypes: A 30-year retrospective survey of neuropathological reports.

We investigated the distribution of neuropathologically defined dementia subtypes among individuals with dementia disorder. The neuropathological reports were studied on all patients (n=524; 55.3% females; median age 80, range 39-102 years) with clinically diagnosed dementia disorder who underwent complete autopsy including neuropathological examination within the Department of Pathology at the Un

Description of ParaSol v3.0 and comparison with measurements

Parasol is a computer program for calculating the solar and thermal properties of windows with sunshades and the energy demands of a room with a window/shading system. The program has three main features. One of them is a calculation of g, T and U for normal incidence of beam irradiation, which is performed as soon as a window or an internal/interpane sunshade is selected. The other two are based

Nature by numbers: an evaluation of how DEFRA’s Biodiversity Metric 3.0 can or cannot capture rewilding outcomes

The United Kingdom’s response to the pressing biodiversity decline in England includes the Biodiversity Net Gain (BNG) policy and is operationalised through DEFRA’s Biodiversity Metric, which quantifies biodiversity into ‘biodiversity units’. This thesis evaluates how effectively the metric reflects real biodiversity outcomes at the rewilded Knepp Estate in West Sussex. Using 2005 as a baseline an

Prostate cancer diagnostics: evolution over 30 years and the impact of education level – a prospective population-based study

Objective: The aim of this study is to describe how the use of diagnostic imagingfor prostate cancer (PCa) has evolved over time and to determine whether thereare any differences in access to diagnostic imaging, type of cancers detected, andmortality based on the education level of patients.Methods: 11,063 men were recruited between 1991 and 1996 and thenprospectively followed until 2020. All new

Trends in type 1 diabetes incidence between 2007 and 2023 and their association with SARS-CoV-2 infection in a population-based matched cohort study among individuals under 30 years old in Sweden

AIMS/HYPOTHESIS: The incidence of type 1 diabetes increased during the pandemic in various countries. SARS-CoV-2 infections may trigger the development of type 1 diabetes, but the evidence is inconclusive. This study aimed to assess trends in type 1 diabetes incidence between 2007 and 2023, and to quantify the association between SARS-CoV-2 infections and the risk for developing type 1 diabetes.ME

Branding in the Metaverse: Exploring established brand management perspectives and the advent of decentralized branding on Web 3.0

Purpose: The purpose of this exploratory qualitative research is: First, to explore what brands understand by metaverse and how they perform branding in this new context. Second, to investigate how established constructivist approaches to branding are performed within the metaverse. And finally, to define what decentralized branding is and how it is linked to a decentralized metaverse. Additionall

Comparison between model-based RSA and an AI-based CT-RSA : an accuracy study of 30 patients

Background and purpose — Radiostereometry (RSA) is the current gold standard for evaluating early implant migration. CT-based migration analysis is a promising method, with fewer handling requirements compared with RSA and no need for implanted bone-markers. We aimed to evaluate agreement between a new artificial intelligence (AI)-based CT-RSA and model-based RSA (MBRSA) in measuring migration of