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Effects of 10 to 30 years of lithium treatment on kidney function.

Long-term lithium treatment is associated with end-stage renal disease, but there is little evidence of a clinically significant reduction in renal function in most patients. We previously found that 1.5% of people who took lithium from the 1960s and 1970s developed end-stage renal disease; however, none of the patients who started after 1980 had end-stage renal disease. Here we aimed to study the

Increased cancer risks among arthroplasty patients: 30year follow-up of the Swedish Knee Arthroplasty Register.

BACKGROUND: An increasing number of young patients are undergoing knee arthroplasties. Thus, the long-term risks of having a knee prosthesis must be evaluated. This study focuses on the potential carcinogenic effects of the prosthesis; it is a long-term follow-up of all patients in Sweden between 1975 and 2006. METHODS: The incidence of cancer in a total population of operated individuals was comp

Instruments for a European Extremely Large Telescope: the challenges of designing instruments for 30- to 100-m telescopes

Designs for Extremely Large Telescopes (ELTs) are quite well advanced,but the requirements of instruments have had limited impact. Sinceprovision of a suitable environment for instruments is a critical aspectof all telescopes, we outline some well-known and some less-appreciatedchallenges of designing instruments for ELTs. A wide-field spectrometer(WFSPEC) with ~10 arcmin field-of-view, probably w

A 30dBm PA for MTC Communication in 65nm CMOS Technology

In this paper the feasibility of using a fully integrated 65nm CMOS PA in future machine-type communication standards has been investigated. The integrated PA investigated shows a linear output power in VSWR 2:1 of minimum 24dBm. A VSWR of 2:1 with an associated 3.1dB front-end insertion loss corresponds to a VSWR of 5:1 at the antenna, which is a conservative number. The PAE at 1dB compression po