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Background: A varying response to cholinesterase inhibitor (ChEI) treatment has been reported among patients with Alzheimer's disease (AD). Whether the individual-specific response, specific ChEI agent or dose affects mortality is unclear. We aimed to examine the relationship between the 6-month response to ChEI and lifespan. Methods: Six hundred and eighty-one deceased patients with a clinical AD
The paper is aimed at the description of the newly introduced model used to simulate the neural response to the chemical stimulus. A potential difference across the living cell or tissue depends usually on the chemical excitation of this living entity. The peculiar case of chemical excitation is the odour recognition across animal kingdom, in particular by various insects. A potential difference i
Titanium is widely used clinically, yet little is known regarding the effects of modifying its three-dimensional surface geometry at the nanoscale level. In this project we have explored the in vivo response in terms of nitric oxide scavenging and fibrotic capsule formation to nano-modified titanium implant surfaces. We compared titanium dioxide (TiO(2)) nanotubes with 100nm diameters fabricated b
The University Board is the highest decision-making body of the University. Its role is to "supervise all matters concerning the higher education institution" and it is "responsible for the performance of its duties", according to the Higher Education Act, Chapter 2, Section 2. The University Board consists ofthe Vice-Chancelloreight community representatives appointed by the Swedish Government, o
https://www.lunduniversity.lu.se/about-university/management-and-organisation/university-board - 2026-06-27
Introduction: Divers are reported to have a lower ventilatory response to elevated levels of carbon dioxide (CO₂) than non-divers. Hypoventilation with CO₂ retention during diving is potentially dangerous. It is unknown if CO₂ retention is largely inherited or develops during diving training. We aimed to investigate if a military dive training course would influence the ventilatory response to CO₂
Introduction Angiotensin-receptor blockers may exert favourable anti-arrhythmic effects in atrial fibrillation (AF), but their mechanisms are not fully understood. In this study, we tested the hypotheses that (i) candesartan reduces atrial fibrillatory rate and (ii) fibrillatory rate and its response to candesartan are related with the outcome of cardioversion. For this purpose, a post hoc subanal
In a 2007 article, Hathaway relaunched his proposal of a multilateral refugee protection system based on the idea of ‘common but differentiated responsibility’. The 2007 article and an earlier, similar article of 1997 both observe that the proposed system will not provide a back door to ‘permanent immigration’ for refugees.In the proposals, all remaining migration movements are subjected to the co
This thesis aims to explore social work practices in relation to sex work. It addresses the research question of what challenges, trends and implications evolve for professional social work in Germany once effective practices in response to prostitution have been identified. These issues are explored through the method of qualitative interviews. The study uses social stigma theory as a theoretica
As Cooren and Sandler note in their paper, communication studies has largely received Bakhtin as a theorist of dialogue, but such a framing limits his potential contributions to our thinking. They argue that when we seek to understand the communicative constitution of reality, Bakhtin's work can lead us in novel and fruitful directions. I find their claims compelling, and thus this response is mor
GABA is the main inhibitory neurotransmitter in the mammalian CNS. GABA in the brain is commonly associated with a fast, point-to-point form of signalling called synaptic transmission (phasic inhibition), but there is growing evidence that GABA participates in another, slower and more diffuse form of signalling often referred to as tonic inhibition. Unresolved questions regarding tonic neuronal in
Studies report that urticarial dermographism is exacerbated by "life events" and emotions. The aim of this study was to determine what aspects of life quality are affected by symptomatic dermographism and whether acute stress is a potential triggering factor. A total of 21 adult patients with urticarial dermographism completed a questionnaire on symptoms and quality of life. Twelve patients agreed
1. A 6-year study (1992-97) of changes in submerged vegetation after biomanipulation was carried out in the eutrophicated Lake Finjasjon, Southern Sweden. Ten sites around the lake were revisited each year. At each site five samples of above-ground biomass were taken at 10 cm water depth intervals. An investigation of the seed bank at the 10 sites, and a grazing experiment where birds and large fi
Popular Abstract in Swedish Kroppens svar på vävnadsskada är avgörande för initierandet av läknings-processen och försvaret mot invaderande mikroorganismer. Det lokala samspelet mellan de olika cellerna i immunförsvaret sker genom cellsignalering via små proteiner kallade cytokiner. Ett kraftigt eller obalanserat svar kan medföra att inflammationsdrivande cytokiner (IL-6, IL-1, TNF) läcker ut i blCell-signalling via cytokines modulates the local response to surgical trauma, directs the immunologic response and initiates the healing process. Surgical trauma induces a systemic cytokine response and a down-regulation of the antigen presentation capacity of monocytes (HLA-DR expression), which is associated with a poor prognosis if pronounced. The aims with the studies in this thesis were to i
Rewetting a dry soil can result in two response patterns of bacterial growth and respiration. In type 1, bacterial growth starts to increase linearly immediately upon rewetting and respiration rates are highest immediately upon rewetting. In type 2, bacterial growth starts to increase exponentially after a lag period with a secondary increase in respiration occurring at the start of the exponentia
