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A set of measurements for the production of a W-boson in association with high-transverse-momentum jets is presented using 140 fb-1 of proton–proton collision data at a centre-of-mass energy of s=13 TeV collected by the ATLAS detector at the LHC. The measurements are performed in final states in which the W-boson decays into an electron or muon plus a neutrino and is produced in association with j
Climate change is increasingly recognized as a major security concern, with drought–migration–conflict linkages attracting significant attention in both policy and research. While some narratives portray drought as a direct driver of migration and conflict, evidence shows a far more complex relationship: climate stress can lead to more migration in some contexts and less in others, with internal m
There is widespread recognition of the need for new homes to feature only low or zero-carbon (LZC) heating. However, residential developers continue to choose conventional high-carbon options such as natural gas boilers over net-zero compatible alternatives. This study explores how UK local authorities (LAs) within the English planning system can encourage residential developers to deploy LZC heat
3I/ATLAS is the third interstellar object discovered to date, following 1I/‘Oumuamua and 2I/Borisov. Its unusually high excess velocity and active cometary nature make it a key probe of the Galactic population of icy planetesimals. Understanding its origin requires its past trajectory through the Galaxy to be traced and the possible role of stellar encounters to be assessed, both as a potential or
This thesis examines how the environmental, regulatory, and social problems arising from U.S.– Malaysia plastic waste trade were represented following China’s 2018 National Sword policy and Malaysia’s eventual 2025 restrictions on plastic waste imports. Rather than treating plastic waste trade as only a material flow, this study seeks to analyze how different actors constructed meaning through com
Background Prostate-specific membrane antigen (PSMA)-PET usage in patients with prostate cancer is growing rapidly. Thus, novel risk-group definitions based on PSMA-PET are urgently needed for guidelines, clinical use, and trial study design. We report improved risk classification based on PSMA-PET Prostate Cancer Molecular Imaging Standardized Evaluation (PROMISE; PPP) nomograms (PPP3) to prognos
Rectal cancer is a common cancer, with presently a 5-year survival of 67 %. Treatment is based on tumor stage, but current staging methods, such as magnetic resonance imaging (MRI) or ultrasound, are limited in the ability to correctly stage the disease. Magnetomotive ultrasound is a developing modality that has a potential to improve rectal cancer staging. Magnetic nanoparticles are set in motion
Background: Optimal reconstruction of the perineal defect after extended abdominoperineal excision remains uncertain, and randomized comparisons between biological mesh and myocutaneous flaps are lacking. This trial assessed whether an acellular porcine collagen implant (APCI) is non-inferior to a gluteus maximus myocutaneous flap (GMF) for pelvic floor reconstruction. Methods: NEAPE was a multice
Cerebrospinal fluid (CSF) enters the brain along perivascular spaces in a manner that depends on aquaporin-4 (AQP4) polarization, facilitating brain clearance and is called the glymphatic system. While physiological factors such as cardiovascular activity and respiration are known to influence glymphatic function, the effects of hypothermia remain poorly understood. In this study, we used quantita
The effects of varying extracellular concentrations of K+ and Ca2+ [K+]o and [Ca2+]o on force development and membrane potential were investigated in the guinea-pig mesotubarium. At [K+]o up to 40 mM, spontaneous action potentials were present, while higher [K+]o gave sustained contractures at a stable membrane potential (-24 to -12 mV for [K+]o from 60 to 120 mM). Tension decreased successively w
Since akinete germination is triggered by light and the action spectrum for this process has features in common with the spectra of the two photochromic pigments, phycochromes b and d, a search was made for the presence of these phycochromes in akinetes of the blue-green alga. Anabaena variabilis Kützing. Allophycocyanin-B was also looked for, since the action spectrum for akinete germination poin
The aim was to investigate the influence of age and gender on quality of life (QoL), complaints, and the presence and nature of self-reported diseases in persons aged 75 and older with cancer (n = 150), compared to a matched group without cancer (n = 138). A second aim was to investigate factors associated with poor QoL in people aged 75 and older. QoL was measured with Short Form (SF-12) and Euro
Heterocyclic amines are mutagenic/carcinogenic compounds that are found in cooked meat and fish. These compounds are of concern in the aetiology of human cancer and therefore it is important to minimise their formation during cooking, and their intake. PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine, CAS no: 105650-23-5) is one heterocyclic amine that is found at high levels in cooked chick
Defect reactions associated with the elimination of divacancies (V-2) have been studied in n-type Czochralski (Cz) grown and float-zone (FZ) grown Si crystals by means of conventional deep-level transient spectroscopy and high-resolution Laplace deep-level transient spectroscopy (LDLTS). Divacancies were introduced into the crystals by irradiation with 4 MeV electrons. Temperature ranges of the di
Enamel matrix derivative, obtained from developing porcine teeth, is composed mainly of amelogenin proteins and used topically in periodontal surgery for advanced periodontitis to regenerate lost connective tissues. The primary objective of this study was to investigate the effects of enamel matrix derivative on skin wound healing. Secondly, in vitro effects of enamel matrix derivative on dermal f
Seventeen ETV6/RUNX1-positive pediatric acute lymphoblastic leukemias were investigated by high-resolution array-based comparative genomic hybridization ( array CGH), gene expression profiling and fluorescence in situ hybridization. Comparing the array CGH and gene expression patterns revealed that genomic imbalances conferred a great impact on the expression of genes in the affected regions. The
The effects of the chaotrophic anion perchlorate (ClO4-) on glucose-induced electrical activity, exocytosis and ion channel activity in mouse pancreatic B-cells were investigated by patch-clamp recordings and capacitance measurements. ClO4- stimulated glucose-induced electrical activity and increased the action potential frequency by 70% whilst not affecting the membrane potential when applied in
Purpose: To describe the clinical phenotype of the complete type of X-linked congenital stationary night blindness (CSNB1) with different types of mutations in the NYX gene. Methods: The clinical and genetic data from 18 male patients with eight different mutations from two ophthalmological institutes were reviewed. The variability in refractive error, reduced visual acuity and full-field electror
