Filetype
Precarious employment (PE) has been linked to adverse health effects, possibly mediated through psychosocial hazards. The aim of this cross-sectional study is to explore if higher levels of PE are associated with psychosocial hazards (experiences of violence, sexual harassment, bullying, discrimination, high demands, and low control) and to explore gender differences in these patterns. The study i
This overview of progress made in preventing post-traumatic osteoarthritis (PTOA) was delivered in a workshop at the Orthopaedics Research Society Annual Conference in 2019. As joint trauma is a major risk factor for OA, defining the molecular changes within the joint at the time of injury may enable the targeting of biological processes to prevent later disease. Animal models have been used to te
OBJECTIVE: To identify and characterize genetic loci associated with the risk of developing anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV).METHODS: Genetic association analyses were performed after Illumina sequencing of 1,853 genes and subsequent replication with genotyping of selected SNPs in a total cohort of 1110 Scandinavian cases with granulomatosis with polyangiit
A combination of genetic and functional approaches has identified three independent breast cancer risk loci at 2q35. A recent fine-scale mapping analysis to refine these associations resulted in 1 (signal 1), 5 (signal 2), and 42 (signal 3) credible causal variants at these loci. We used publicly available in silico DNase I and ChIP-seq data with in vitro reporter gene and CRISPR assays to annotat
INTRODUCTION: The optimal bowel preparation strategy to minimise the risk of anastomotic leak is yet to be determined. This study aimed to determine whether oral antibiotics combined with mechanical bowel preparation (MBP+Abx) was associated with a reduced risk of anastomotic leak when compared to mechanical bowel preparation alone (MBP) or no bowel preparation (NBP).METHODS: A pre-planned analysi
ObjectivesThe aims of the study were to investigate the prevalence of impaired sensation after minor salivary gland biopsy (MSGB) in two Swedish centres [Karolinska University Hospital (KUH) and Skåne University Hospital (SUH)] and to assess its impact on quality of life (QoL) and associated risk factors.MethodA questionnaire including questions regarding the presence of impaired sensation, impact
Background Cutaneous leishmaniasis (CL) is frequent in travellers and can involve oro-nasal mucosae. Clinical presentation impacts therapeutic management. Methodology Demographic and clinical data from 459 travellers infected in 47 different countries were collected by members of the European LeishMan consortium. The infecting Leishmania species was identified in 198 patients. Principal findings C
Context: Insulin resistance in skeletal muscle is a major risk factor for the development of type 2diabetes in women with polycystic ovary syndrome (PCOS). Despite this, the mechanisms underlyinginsulin resistance in PCOS are largely unknown.Objective: To investigate the genome-wide DNA methylation and gene expression patterns inskeletal muscle from women with PCOS and controls and relate them to
Temporary work agencies operate on a business model based on the idea of hiring workers and placing them in assignments at other companies. This model has proved to be beneficial on the labour market in response to the increasing competitive pressure, the need of flexibility and a bigger variation of workforce. The Swedish labour law model is traditionally built on an employment contract between a
Sammanfattning Examenarbetets titel: Personal branding – möjlighet eller krav? Seminariedatum: 2015-01-15 Ämne/kurs: FEKH29 Företagsekonomi: Examensarbete i marknadsföring på kandidatnivå, 15 högskolepoäng Författare: Magnus Skog, Justus Jahja, Niran Ahmad Handledare: Jon Bertilsson Nyckelord: Sociala medier, varumärke, företagsledare, finansiellt resultat Syfte: Uppsatsens syfte är att i eAbstract Title: Personal branding – opportunity or necessity? Seminar date: 2015-01-15 Course: FEKH29 Business administration: Degree Project in Marketing, Undergraduate Level, 15 hp. Authors: Magnus Skog, Justus Jahja, Niran Ahmad Advisor: Jon Bertilsson Key words: Social media, brands, Ceo, financial result Objective: The objective of this thesis is to in an explorative approach obtain th
BACKGROUND: The transradial approach is associated with fewer bleeding complications during percutaneous coronary interventions (PCIs) but is more technically challenging and associated with prolonged times during intervention. The aim of this study is to retrospectively compare the results of radial vs. femoral approach in patients >or=80 years old undergoing primary or rescue PCI.METHODS: Betwee
This paper aimed to study the agreement and repeatability, both intra- and interobserver, of infrapopliteal lesion assessment with magnetic resonance angiography (MRA), using the TransAtlantic Inter-Society Consensus (TASC) II criteria, with perioperative digital subtraction angiography (DSA) as a reference. Sixty-eight patients with an MRA preceding an endovascular infrapopliteal revascularizatio
Lignin, the world's most abundant biopolymer with high aromaticity, has huge potential as a renewable feedstock replacing petroleum for the production of chemicals, fuels and functional materials. The enhanced utilization of lignin would improve the economic viability of existing pulp and paper mills, as well as lignocellulosic biorefineries, where lignin is highly available, but mostly incinerate
One can falsely assume that it is well known that bacteremia is associated with higher mortality in sepsis. Only a handful of studies specifically focus on the comparison of culture-negative and culture-positive sepsis with different conclusions depending on study design. The aim of this study was to describe outcome for critically ill patients with either culture-positive or -negative sepsis in a
Background: Cure proportion represents the proportion of patients who experience the same mortality rate as the general population and can be estimated together with the survival of the proportion experiencing excess mortality (the uncured). The aim was to estimate the cure proportions and survival among uncured stage II–III cutaneous melanoma (CM) patients. Methods: 1‐ and 5‐year relative surviva
Background The number and rank order of siblings could be of importance for risk of cardiovascular disease and mortality. Previous studies have used only fatal events for risk prediction. We, therefore, aimed to use also non-fatal coronary and cardiovascular events in fully adjusted models. Methods From the Multiple-Generation Register in Sweden, data were used from 1.36 million men and 1.32 milli
Hearing impairment most often involves loss of sensory hair cells and auditory neurons. As this loss is permanent in humans, a cell therapy approach has been suggested to replace damaged cells. It is thus of interest to generate lineage restricted progenitor cells appropriate for cell based therapies. Human long-term self-renewing neuroepithelial stem (lt-NES) cell lines exhibit in vitro a develop
