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We evaluated asthma control and medication use 5 years after introduction of an inhaled corticosteroid (budesonide via Turbuhaler(R)) in 462 patients with persistent asthma and symptoms of different duration. An early treatment group with symptoms for <2 years (group A) was compared with a delayed treatment group (group B) (median duration 5 years and 3 months). Most patients received budesonide 4
The aim of this study was to develop a model for the quantification of the occupant risk in residential fires. The model should make it possible to quantitatively evaluate which effect the presence of a residential sprinkler has on the fire development. Statistics on causes and outcomes of residential fires were used as background material for the model development. A literature review was carried
Variation in sex hormone exposure during early embryonic development contributes to individual differences in behaviour and cognitive abilities later in life. Digit ratio has gained considerable interest as a putative marker for early androgen/oestrogen exposure in behavioural ecology research. Studying digit ratio in nonhuman laboratory as well as wild vertebrate species may be useful to assess w
After a long period of focus on western and East Asian scripts there is now a general trend in the on-line handwriting recognition community to explore recognition of other scripts such as Arabic and various Indic scripts. One difficulty with the Arabic script is the number and position of diacritic marks associated to Arabic characters. This paper explores the application of a template matching s
The cellular tumor suppressor p16 is strongly overexpressed in cervical cancers and precancers. We have previously demonstrated that infiltrating T lymphocytes reactive against p16 can be found in cervical cancer patients. Here, we analyzed whether 16 induces humoral immune responses. Sera of patients with cervical cancer, oropharyngeal cancer, colorectal cancer and autoimmune disease were include
With the growing interest in clinical interventions that involve medical devices, the role for new biomaterials in modern medicine is currently expanding at a phenomenal rate. Failure of most implant materials stems from an inability to predict and control biological phenomena, such as protein adsorption and cell interaction, resulting in an inappropriate host response to the materials. Contempora
Agricultural policies have always had a tendency to be controversial. In many cases they generate major transfers of welfare between different groups of people, and hence are favoured by some and criticised by others. They also frequently cause trouble at the international level as domestic programmes interfere with trade flows and affect the wellbeing of people in other parts of the world. In add
Factor VIII (FVIII)-bypassing agents have complex modes of action but all control bleeding in inhibitor patients by triggering the generation of thrombin. No routine test is available for monitoring this therapy in patients with inhibitors against FVIII. We present an assay that records FEIBA- or FVIIa- mediated changes in thrombin generation (TG) in FVIII inhibitor plasma samples. In plasma sampl
Object. Cerebral pressure autoregulation is an important neuroprotective mechanism that stabilizes cerebral blood flow when blood pressure (BP) changes In this study the authors examined the association between autoregulation and clinical factors. BR. intracranial pressure (ICP), brain tissue oxygen tension (PbtO(2)), and outcome after pediatric severe traumatic brain injury (TBI). In particular w
The process of continuous sedimentation of particles in a liquid has often been predicted by means of operating charts and mass-balance considerations, where the underlying constitutive assumption is the one by Kynch. Much more complex operating charts (concentration-flux diagrams) can be obtained from a one-dimensional model of an ideal continuous clarifier-thickener unit. The engineering concept
A model for an electric infrared (IR) heater has been developed. The model includes non-grey radiative heat transfer between the different parts of the IR heater, as well as conduction in reflector material and convective cooling of surfaces. The geometry is simplified into one dimension. Using IR module voltage, as the only input, the model predicts the temperature of heater components and coolin
Purpose: Promoter hypermethylation of, for example, tumor-sup pressor genes, is considered to be an important step in cancerogenesis and a negative risk factor for survival in patients with myelodysplastic syndromes (MDS); however, its role for response to therapy has not been determined. This study was designed to assess the effect of methylation status on the outcome of conventional induction ch
Five ectomycorrhizal fungi were studied in relation to the effects of applications of lime and wood ash to the growth substrate. Growth and survival of inoculated fungi in unsterile humus and relative root colonization frequency by inoculated and indigenous ectomycorrhizal fungi were measured. Growth of the fungi was tested in Petri dish systems with humus taken from a field site treated with lime
Aims/hypothesis: The study evaluated whether glucagon secretion is regulated by changes in insulin sensitivity under normal conditions. Materials and methods: A total of 155 healthy women with NGT (aged 53-70 years) underwent a glucose-dependent arginine-stimulation test for evaluation of glucagon secretion. Arginine (5 g) was injected i.v. under fasting conditions (plasma glucose 4.8 +/- 0.1 mmol
We examined the attractiveness of a natural headspace sample of [i]Platanthera bifolia[/i blossoms, synthetic blends and Single compounds to the silver Y moth, Autographa gamma, in a flight tunnel. The synthetic blend consisted of previously identified electrophysiologically active compounds from P. bifolia: benzyl benzoate, benzyl salicylate, cinnamyl alcohol, lilac aldehydes, methyl benzoate and
An AC-voltage source feeding an electric network results ina periodic excitation of the network. In steady state, allcurrents and voltages will be periodic with cycle time corresponding to thefrequency of the voltage source. If the network is linear, all signalsare sinusoidal and the network is solved using traditional methods.If the network contains components with nonlinear or switchingdynamics,
Abstract in UndeterminedSo-called fitting-attitude analyses or buck-passing accounts of value have lately received much attention among philosophers of value. These analyses set out from the idea that values must be understood in terms of attitudinal responses that we have reason to or that it is fitting or that we ought to have regarding the valuable object. This work examines to what extent this
Amperometric biosensors based on corresponding dehydrogenases have been developed for the determination of ethanol, glucose and glycerol. The enzymes have been integrated in redox hydrogels using an Os complex-modified non-conducting polymer employed as the electrochemical mediator and poly(ethyleneglycol)-diglycidyl ether (PEGDGE) as the cross-linking agent. The developed biosensors showed a sens
OBJECTIVE. To evaluate the recurrence of foot ulcers as well as the cumulative amputation and mortality rates in diabetic patients with previous foot ulcers. DESIGN. A prospective study of consecutively presenting diabetic patients admitted to the Department of Internal Medicine because of foot ulcer with a median follow-up of 4 years. SETTING. A multidisciplinary foot-care team. POPULATION. Five-
