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Factor VIII (FVIII)-bypassing agents have complex modes of action but all control bleeding in inhibitor patients by triggering the generation of thrombin. No routine test is available for monitoring this therapy in patients with inhibitors against FVIII. We present an assay that records FEIBA- or FVIIa- mediated changes in thrombin generation (TG) in FVIII inhibitor plasma samples. In plasma sampl
Lacunar infarcts--small subcortical infarcts that result from occlusion of a single penetrating artery--account for about one quarter of all ischaemic strokes. However, there are many diagnostic pitfalls, and causes other than penetrating small vessel disease in up to one third of cases. Recent studies have shown that the prognosis after lacunar infarcts is not benign; the risk of recurrent stroke
Concentrations of NO2 and O3 were measured inside and outside a dense broad-leaved forest canopy adjacent to a busy traffic route in the City of Gothenburg, Sweden, with duplicate passive diffusion samplers during six one-week periods starting well before leaf senescence and ending when leaves were largely senescent. Concentrations of NO2 were lower inside the forest canopy during all periods (rep
The aim of this study was to develop a model for the quantification of the occupant risk in residential fires. The model should make it possible to quantitatively evaluate which effect the presence of a residential sprinkler has on the fire development. Statistics on causes and outcomes of residential fires were used as background material for the model development. A literature review was carried
Amperometric biosensors based on corresponding dehydrogenases have been developed for the determination of ethanol, glucose and glycerol. The enzymes have been integrated in redox hydrogels using an Os complex-modified non-conducting polymer employed as the electrochemical mediator and poly(ethyleneglycol)-diglycidyl ether (PEGDGE) as the cross-linking agent. The developed biosensors showed a sens
A method for the simultaneous determination of N-methyl-2-pyrrolidone (NMP) and its metabolites 5-hydroxyl-N-pyrrolidone (5HNMP), N-methylsuccinimide (MSI) and 2-hydroxy-N-methylsuccinimide (2HMSI) in plasma and urine has been developed. Samples were purified by SPE using an ASPEC XL4. Analysis was performed using LC-MS equipped with an APCI interface. The analysis provided linear responses in the
Information on floral resource costs is fundamental for understanding how selection operates on floral morphology. In this study, I explored the cost of maturing flowers in a self-incompatible population of the ligulate composite Crepis tectorum L. by experimentally manipulating floral investment and then monitoring the response in reproductive effort. Plants on which the heads were removed during
Predator-prey interaction strengths in variable environments constitute a fundamental link to the understanding of aquatic ecosystem responses to environmental change. The present study investigates the effects of visibility conditions and prey fish density on predation rates of visually oriented piscivorous Eurasian perch Perca fluviatilis L. This was done in outdoor mesocosm (16 m(2)) experiment
Ever since the end of the Cold war, there has been a change in what is considered a security threat. A discourse of security is traditionally linked to military threats; however, it has become more and more visible in migration policies. In the past ten years, a discourse of humanitarianism has also gained momentum and is often used in connection to a security discourse. In this thesis, I have exa
Denna studie har undersökt hur ett företags medarbetares återhämtning ser ut och dess samband med förväntningar och förlängd jobbtillgänglighet. Friskvårdsbidrag och fritidsförlagd arbetstid har även undersökts i relation till återhämtning. Undersökningen gjordes genom en webbaserad enkät som skickades ut via företagets HR-personal. Utav populationen bestående av 25 medarbetare deltog 11. ResultatThis study has examined how co-workers in a company recover and how their recovery is connected to expectations and extended work availability. The use of the Swedish wellness grant and work during leisure is examined in relation to recovery. The study was executed through an internet survey and was sent out through the company's HR department. Out of a total population of 25, a total of 11 co
More and more structural analyses today are being conducted with computer-based tools in comparison to traditional methods using hand calculations. The development, according to the Norweigan scientist Kolbein Bell is shifting from using first order analyses with correction factors, to using second order analyses, with computer-based tools. This dissertation mainly compares analyses of glulam colu
The International Association of Fire Safety Science (IAFSS) is comprised of members from some 40 countries. This paper presents the Association's thinking, developed by the Management Committee, concerning pressing research needs for the coming 10 years presented as the IAFSS Agenda 2030 for a Fire Safe World. The research needs are couched in terms of two broad Societal Grand Challenges: (1) cli
Foetal and neonatal alloimmune thrombocytopenia (FNAIT) is the platelet counterpart of haemolytic disease of the foetus and newborn. Among Caucasians, around 80 % of FNAIT cases and some of the most severe cases, are caused by alloantibodies against the human platelet antigen 1a (HPA-1a). For around 3 decades it has been known that almost all HPA-1a-immunised women are HLA-DRB3*01:01 positive. The
Urban densification, despite the economic and social opportunities it offers, brings with it challenges to the well-being of citizens. A direct effect of densification is the rise in noise- and vibration-producing sources, which can lead to both health and comfort issues. In determining the risk associated with excessive vibration levels, the distance between the source and the receiver or target
The number of evacuees worldwide during wildfire keep rising, year after year. Fire evacuations at the wildland-urban interfaces (WUI) pose a serious challenge to fire and emergency services and are a global issue affecting thousands of communities around the world. But to date, there is a lack of comprehensive tools able to inform, train or aid the evacuation response and the decision making in c
Objective: To facilitate a greater likelihood of favorable response to new disease-modifying therapies, recruitment of patients at an earlier stage of their disease into clinical trials may be an attractive strategy. Hence, there is a need to develop widely accepted classification criteria for early-stage knee osteoarthritis (OA). We have proposed a set of classification criteria for early-stage k
Seventy-nine monoclonal antibodies submitted to the ISOBM TD-3 PSA Workshop were tested for their reactivity with recombinant human kallikrein-2 (rhK2). A sandwich immunofluorometric assay using polyclonal antiprostate- specific antigen (PSA) antiserum-coated plates was used to capture rhK2 and subsequently the test antibody. The response of each test antibody was compared with 3 reference antibod
IMPORTANCE: Correct diagnosis of ovarian cancer results in better prognosis. Adnexal lesions can be stratified into the Ovarian-Adnexal Reporting and Data System (O-RADS) risk of malignancy categories with either the O-RADS lexicon, proposed by the American College of Radiology, or the International Ovarian Tumor Analysis (IOTA) 2-step strategy.OBJECTIVE: To investigate the diagnostic performance
FÖRSÄTTSSIDA STYRDOKUMENT Riktlinjer för fördelning av beslutsbefogenheter samt arbetsformer vid Samhällsvetenskapliga fakulteten Typ av styrdokument: Riktlinjer Definition av typen av styrdokument: Enligt universitetets riktlinjer för styrdokument (STYR 2024/1601) fastställer riktlinjer hur någon ska eller bör handla inom det område riktlinjerna omfattar. En ska-regel ska följas medan en bör-rege
https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2026-02/beslut-delegationsordning-20260212.pdf - 2026-07-02
Årsrapport 2020 KOO Å R S R A P P O R T · K O M M U N I K A T I V A O F F E N T L I G A O R G A N I S A T I O N E R Kommunikativt medarbetarskap Rickard Andersson, Mats Heide och Charlotte Simonsson Institutionen för strategisk kommunikation Lunds universitet · april 2021 © Rickard Andersson, Mats Heide och Charlotte Simonsson 2021 Institutionen för strategisk kommunikation Lunds universitet ISBN
https://www.isk.lu.se/sites/isk.lu.se/files/2021-04/Kommunikativt%20medarbetarskap.pdf - 2026-07-02
