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Dilatory responses of extracellular nucleotides were examined in the precontracted isolated rat mesenteric artery. Dilatation mediated by endothelium-derived hyperpolarising factor (EDHF) was studied in the presence of Nomega-nitro-L-arginine (L-NOARG) and indomethacin, and was most potently induced by the selective P2Y(1) receptor agonist adenosine 5'-O-thiodiphosphate (ADPbetaS), while 2-methylt
We reported previously the formation of microtears in an in vivo loaded Flexor Digitorum Profundus (FDP) rabbit tendon with a repetition rate of 60 repetitions per minute and a peak force of 15% of maximum peak tetanic force for 80 cumulative hours. Tear area as a percent of tendon area, tear density (tears/mm(2)), and mean tear size (mu m(2)) were higher in tendons from the loaded limb compared t
An integrative approach to managing host–parasite interactions that threaten species communities will benefit from identifying variation in parasite impact across host species, and host–parasite responses to annual climatic variation. We examine interannual, inter- and intraspecific variation in Philornis downsi intensity – an introduced blood sucking fly that causes high fitness costs in Darwin’s
BACKGROUND: Endotoxin (lipopolysaccharide, LPS) up-regulates inducible nitric oxide synthase (iNOS) in blood vessels during septic shock. This promotes the production of nitric oxide (NO), leading to dilation of the vessels. The aim of the study was to investigate the effects of the LPS-binding endogenous antibiotic bactericidal/permeability-increasing protein (BPI) on the action of LPS on the blo
Background and purpose: beta(2)-Adrenoceptor agonists (beta(2)-agonists) are important bronchodilators used in the treatment of asthma and chronic obstructive pulmonary disease. At the molecular level, beta(2)-adrenergic agonist stimulation induces desensitization of the beta(2)-adrenoceptor. In this study, we have examined the relationships between initial effect and subsequent reduction of respo
Introduction Assessing work ability and sickness certification are considered problematic by many physicians and education and implementation of guidelines to improve knowledge and skills has been requested. Our aim was to study the association between such interventions and physicians' sick-listing practices. Methods A web-based questionnaire was sent to all physicians working in primary care, ps
Little is known about the association between self-reported academic performance and risky sexual behaviors and if this differs by gender, among university students. Academic performance can create psychological pressure in young students. Poor academic performance might thus potentially contribute to risky sexual behavior among university students. The aim of this study was to investigate the ass
Popular Abstract in Swedish Sammanfattning på Svenska: Avhandlingen handlar om tvångsvård av alkoholister och presenterar såväl metodologiska som kliniska studier av behandlingsutfall. Innebörd av tvångsvård Alkoholister kan uppleva många olika typer av påtryckning för att gå in i behandling. Fysisk och psykisk smärta, sociala påtryckningar från närstående eller arbetsgivare, samt olika typer avThis thesis concerns involuntary social treatment for alcoholism. Alcoholics who were compulsorily committed according to the Swedish Act of Care of Addicts in Certain Cases (LVM) were treated together with voluntary patients. They were followed up by mail questionnaires to patients, significant others and social workers. Self-reports were in satsifactory agreement with collateral reports concerni
Aim: Hearing loss (as reflected by abnormal sound detection) is a frequently reported consequence of Type 1 diabetes mellitus. We sought to evaluate sound detection, auditory neural function and binaural processing ability in a group of school-aged participants with Type 1 diabetes and to assess their functional hearing and general communication ability. Methods: A range of electroacoustic, electr
Polyelectrolyte adsorption and polymer mediated interactions in different colloidal polymer systems have been studied in this work. Theoretical methods and experimental techniques are combined, in order to obtain more general reliable results, as well as a deep understanding of the molecular mechanisms that are responsible for the observed behaviors. Two different types of highly charged cationic
Computational models are commonly used to investigate how the cortical bone microstructure affects fracture resistance; recently, phase-field models have been introduced for this purpose. However, experimentally measured material parameters for the microstructural tissues are lacking. Moreover, as no validation studies have been published, it remains unclear to what extent classical phase-field me
In this research, we develop three statistical based control charts: the Hotelling's T2, MEWMA (multivariate exponentially weighted moving average), and LRT (likelihood ratio test) as well as three machine learning (ML) based control charts: the ANN (artificial neural network), SVR (support vector regression), and RFR (random forest regression), for monitoring generalized linear model (GLM) profil
AimTo explore inter-country variation of factors associated with institutionalization of people with dementia. BackgroundThere is an urgent need for evidence on whether factors associated with admission to institutional dementia care are applicable across healthcare systems, as increasing evidence suggests that these factors could be country-specific. DesignA prospective cohort study. MethodPrimar
Objective: To compare responsiveness based on item response theory (IRT) with that based on conventional scoring for two patient-reported outcomes measures in carpal tunnel syndrome (CTS); the short disabilities of the arm, shoulder, and hand (QuickDASH) measure, and the 6-item CTS symptoms scale (CTS-6). Study Design and Setting: Prospective cohort study of patients with CTS undergoing carpal tun
OBJECTIVE: The present study assessed somatosensory changes related to trigeminal nerve damage using extensive evaluation tools and assessed the effect of such damage on the patients' psychosocial status and quality of life compared with healthy participants.METHODS: In 37 patients with intraorally or extraorally presenting trigeminal nerve damage diagnosed as painful or nonpainful posttraumatic t
Lund University in brief 2022 Lund University 2022 | EDUCATION, RESEARCH AND COLLABORATION SINCE 1666 A WORLD-CLASS UNIVERSITY To understand, explain and improve Lund University was founded in 1666 and, ever since, has been a centre of culture and learning. One of our strengths is our unique disciplinary range and our ability to generate boundary-crossing collaboration. Student influence, internat
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-05/Presentationbrochure-2022-ENG.pdf - 2026-07-17
Recent developments on the African continent have indicated the emergence of a comprehensive security framework that has been developed to address the many security issues currently threatening peace and stability. A central pillar in this new framework has been the prominent role played by Regional Economic Communities (RECs) that have increasingly adopted peace and security goals as part of thei
Humanitära interventioner är ett väl debatterat ämne inom internationell rätt. Det är ett ämne som väcker stora känslor och diskussioner bland jurister samt inom och emellan stater världen över. När det gäller legaliteten av humanitära interventioner finns det mycket material att tillgå, dock övergår diskussionen sällan i det som egentligen är viktigast: Borde humanitära interventioner vara lagligHumanitarian interventions is a well debated subject within international law. When it comes to the legality of humanitarian interventions the international community is divided and a lot of material regarding such interventions can be found. Unfortunately, the discussion rarely turns to the more important question: Should humanitarian interventions be legal under contemporary international law? T
In 1975, church sanctuary re-emerged in the Netherlands with a new purpose: to protect asylum seekers from deportation. During church sanctuary events, church sanctuary providers host asylum seekers in or around the church building, operating on the understanding that the government will not enter a church to make arrests. The practice is not illegal, but at the same time is not recognized as a ri
Uppmaningen till att leva hållbart genomsyrar samhället, fast en övergång till hållbara liv är långt ifrån verklighet. Genom att förstå hur individer ser på hållbara liv i relation till välmående kan potentiellt hjälpa människor i övergången till mer hållbara liv. Den här studien var förregistrerad till undersöka valensen av individers syn på en hållbar livsstil, och hur denna synen relaterar tillThe call for living sustainably can be seen in many places throughout society, although a transition towards sustainable lifestyles is far from a reality. Understanding how people view sustainable living in relation to well-being can potentially help individuals in the transition to live more sustainably. This study was pre-registered to examine the valence of how people view sustainable lifestyle
