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Background Systemic sclerosis (SSc) is an autoimmune disease and accumulating evidence suggests a role for Toll-like receptor (TLR)-mediated activation of dendritic cells (DCs). Objective To map TLR-mediated cytokine responses of DCs from patients with SSc. Methods 45 patients with SSc were included. Patients were stratified as having diffuse cutaneous SSc (dSSc) or limited cutaneous SSc (lSSc) ac
Background: Traditional outcome measures in peripheral arterial disease (PAD) provide insufficient information regarding patient benefit. It has therefore been suggested to add patient-reported outcome measures. The main aim of this study was to validate the Swedish Vascular Quality of Life questionnaire (VascuQoL) version, a patient-reported PAD-specific health-related quality of life (HRQoL) ins
Nanostructures have many material, electronic, and optical properties that are not found in bulk systems and that are relevant for technological applications. For example, nanowires realized from III-V semiconductors can be grown into wurtzite crystal structure. This crystal structure does not naturally exist in bulk where these materials form the zinc-blende counterpart. Being able to concomitant
Climate warming profoundly alters cryospheric hydrological cycles, exacerbating the challenge of simulating the poorly understood processes, particularly in complex, glacier- and permafrost-dominated headwater basins. This difficulty centers on accurately representing the compound runoff regimes generated by the complex, overlapping interactions between rainfall and multiple cryospheric melt proce
Commercial sexual exploitation of children (CSEC) has been a major cause of concern in recent years. The term CSEC is used to describe the various activities exploiting children for sexual purposes and includes trafficking of children, child pornography, child prostitution and sex tourism. The sexual exploitation implies that the child is not only sexually abused but that it has a value on a marke
The European Union has decided to standardize the train control command system on the European railways. The reason for the standardization of the train control command system is to increase the competitiveness of the railway by promoting the ability to run the same train from one end of Europe to the other, without the need to change locomotives and drivers. The train control command system that
Celiac disease is a chronic autoimmune disease which affects about 3 % of children in Sweden where most of them have an asymptomatic form making it difficult to detect. The bacterial composition in the gastrointestinal microflora can affect the intestinal barrier properties and the immune systems response to various dietary components. An unfavourable composition of the microflora can activate par
What can we say about the future of art and the exhibition aspects of art? How are art institutions today co-creators in shaping conditions for the future, and how is the network of larger institutions connected to politics, as well as in the shaping of cultural heritage and the identity of a city? This essay examines how discourses for exhibitions are developed among three municipal institutions:
In topology optimization, iterative, gradient-based methods are used to find the material distribution of structures which maximizes some objective function, typically the structures' stiffness, or in some cases the fundamental frequency. Finite element analysis is used to compute the structural response in each iteration, leading to large systems of equations. Several hundred iterations may b
Introduction Major depressive disorder (MDD) is a major global healthcare challenge. This is, in part, due to the lack of treatment response and chronic course of MDD. Such a course of illness is often termed treatment-resistant depression (TRD) and is seen in over one-Third of people with MDD. Reasons for treatment resistance are not well established, nor is the definition of TRD. Duration and se
The TRPV1 receptor (transient receptor potential vanilloid 1) is a nonspecific membrane-bound cation channel, which plays an important role in nociception and pain transmission, the nerve-response to possibly dangerous stimuli. It is known that TRPV1 can be modulated by a variety of stimuli, amongst which heat, protons and chemical compounds, such as capsaicin, are the most known activators. This
Objective: The Dark Factor of Personality (D) measures the underlying core of all aversive traits. The present study evaluated the psychometric properties of the Swedish version of three item sets D70, D35, and 16 in regard to their factor structure, item quality and functioning, reliability, and convergent and discriminant validity. Method: A convenience and prolific sample (N = 294) was analyze
Thesis purpose: The current study examines the association between seven variables: environmental sustainability, perceived functionality, social influence, price value, hedonic motivation, uniqueness, and technology habit with the purchase of second-hand clothing on peer-to-peer platforms on a regular basis. Theoretical perspective: Venkatesh, Thong and Xu’s (2012) Extended Unified Theory of Acc
Verksamhetsberättelse för Körcentrum Syd år 2010 Verksamhetsberättelse för Körcentrum Syd år 2010 Inledning Nedanstående årsredovisning för år 2010 i Körcentrum Syd har fastställts av Körcentrum Syds styrelse, 27 januari 2011. År 2010 var Körcentrum Syds tredje verksamhetsår. Trots en relativt liten budget på drygt 1,7 miljoner kronor, har en stor verksamhet kunnat genomföras. Detta tack vare Körc
https://www.korcentrumsyd.lu.se/sites/korcentrumsyd.lu.se/files/verksamhetsberattelse-for-korcentrum-syd-ar-20101.pdf - 2026-07-12
What are human rights to you? - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme
https://rwi.lu.se/what-are-human-rights-to-you/ - 2026-07-12
Background: Tumour-infiltrating lymphocytes (TILs) that persist in chronic infections gradually lose their effector functions and become “exhausted”. Immune checkpoint blockade is an emerging cancer treatment which aims to induce exhausted TILs into regaining their effector function to fight neoplastic cells. However, response to treatment varies significantly between different cancer types and ma
Over the past few decades, employee engagement has been increasingly recognised as a key driver of organisational success. Although previous research has examined psychological and organisational factors influencing engagement, few studies have examined how it varies over time. This study explores the dynamic and sustainable aspects of employee engagement in Swedish organisations, focusing on how
Lunds kommun har som mål att minska bilberoendet och att vara klimatneutrala år 2030. Med bakgrund i detta, samt en strävan att alla boende i kommunen ska ha tillgång till samma service, finns en önskan från Lunds kommun att undersöka alternativa lösningar till dagens insamling av sällanavfall. Sällanavfall definieras i denna studie som avfall från hushåll som uppkommer mer sällan och vanligtvis sLund municipality aims to decrease the dependency of cars and to be climate neutral by 2030. With this in mind, together with an aspiration that all citizens in the municipality should have access to the same service, Lund municipality wishes to explore alternative solutions to the collection of “seldom waste” that exists today. Seldom waste is in this report defined as waste from households that
Consumers are becoming interested in oats as a healthy food. Several studies have investigated the impact of oats components on human metabolism. The purpose of this project is to study the influence of oat polar lipids on human cardiometabolic variables, which focused on four cardiometabolic variables, these were postprandial responses of glucose, insulin, cortisol, and subjective appetite variab
Introduction: A new method for separation and determination of Glyphosate and Glufosinate alongside their respective major metabolites aminomethylphosphonic acid and 3-(methylphosphinico)propionic acid was found then tested in spiked soil and surface water. Background: Most methods today require derivatization for determination and separation of these compounds. Methods without derivatization rel
