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Neural stem cells (NSCs) in the embryo generate neurons, astrocytes and oligodendrocytes, the principal cells of the central nervous system (CNS), which contribute to the full diversity of the brain. Some NSCs persist in the adult brain and ensures neurogenesis throughout adult life in the subventricular zone (SVZ) and the subgranular zone (SGZ). NSCs in the SGZ generates neurons in the granule ce
Economic and environmental concerns will slow down the expansion of the transmission system in many countries. The addition of new transmission lines will be few and far between. The de-regulation of the power supply will introduce new power flow patterns on the bulk transmission systems. The net result is that the power systems will operate much closer to their transfer limits and operate there m
Popular Abstract in Swedish Att ha en allvarlig hjärtsjukdom är oftast förknippat med oro och rädsla. När det bestäms att patienten ska genomgå en planerad hjärtoperation, kan det vara avgörande för patientens och de närståendes välbefinnande hur de bemöts av all hälso- och sjukvårdspersonal, som de kommer i kontakt med under väntetiden samt vilket stöd de då upplever. Att korrekt och saklig inforPatients waiting for cardiac surgery often consider the period from the decision for surgery to the time for the operation as long, heavy and dreary. Therefore, it is important that patients are supplied with structured oral and written information regarding their disease and its treatment, so that they are able to understand and discuss the forthcoming operation, the risk of complications and the
Sensing and quantification of biomolecules are becoming increasingly important in medical diagnostics, bioprocess technology and recently in homeland security. The majority of techniques currently employed to interrogate biomolecules require some type of radio-, enzymatic- or fluorescent-labeling. However, there is an increasing awareness of novel techniques in which biomolecules are detected in t
In type I diabetes mellitus (T1DM), the frequency of antibodies against insulin (IAA), glutamic acid decarboxylase-65 (GAD65), ICA512/IA2 (IA2), and islet cell antigens (ICA) vary with human leukocyte antigen (HLA) composition of the patient. IAA, IA2 autoantibodies, and ICA are increased in DQ8 positives; GAD65 antibodies are increased in DQ2 positives. MHC class I chain-related gene-A (MICA) is
Popular Abstract in Swedish Laser Doppler metoder avsedda för mätning av blodflöde baserar sig på det faktum att fotoner skiftar i våglängd när de träffar blodkroppar i rörelse. Den förändrade våglängden registreras och signalen bearbetas varefter resultatet uttrycks i en godtycklig enhet och anses utgöra ett mått på blodflöde. Laser Doppler Perfusion Monitoring (LDPM) är en metod med vilken blodThe operating principle of all laser Doppler methods is based on the fact that incident photons shift in wavelength when interacting with moving blood cells passing through the microvascular network. After photodetection and further signal processing, the recorded parameter can be considered an arbitrary measure of tissue blood flow, and this is referred to as ?perfusion?. Laser Doppler perfusion
Return migration is an important phenomenon that involves a large share of all migrants, and has great potential for the enhancement of economic development, for instance through remittances and investments by migrants who are still abroad, and “brain gain” when migrants return with working experience from their former host countries. This paper deals with return migration, by refugee immigrants a
Popular Abstract in Swedish Kloning är inte enbart ett sätt för genetiska ingenjörer att framställa identiskt lika får. Det är framför allt ett naturligt förökningssätt för många djur och växter. Bladlöss, björnbär och backlök är tre exempel på vanliga organismer som förökar sig genom kloning. Enligt gängse evolutionär teori är kloning – eller asexuell reproduktion – ett effektivare sätt att produEvolutionary theory predicts a disadvantage to sexual reproduction. This manifests itself either by the higher growth rate of asexual females in a dioecious species, or by the higher transmission rate of a gene conferring asexual female function to its carriers in a hermaphrodite species. The disadvantage to sexual reproduction may be as high as two-fold provided all else is equal. This phenomenon
Ovarian cancer is a heterogeneous disease and recent advances in improving patient outcome havebeen limited. It is estimated that a woman’s risk of developing ovarian cancer during her lifetime is about 1 in 70, making it a frequently occurring cancer type in women.This thesis investigated biological events in ovarian cancer, which were translated into clinically relevant observations using differ
Recent investigations of the DNA interactions with cationic surfactants and catanionic Mixtures are reviewed. Several techniques have been used such as fluorescence microscopy, dynamic light scattering, electron microscopy, and Monte Carlo simulations. The conformational behaviour of large DNA molecules in the presence of cationic surfactant was followed by fluorescence microscopy and also by dyna
Part of the justification for an integrated view of speech and gestures ( (( is their temporal coordination. Gestures generally coincide with or precede, but rarely follow lexical affiliate (McNeill, 1992). How synchrony impacts listeners remains less explored, despite potential relevance for video communication and virtual conversational agents. ERP studies suggest that temporal alignment affects
Background: Among pediatric patients, newborns are at highest risk of developing thromboembolism. Neonatal thromboembolic (TE) events may consist of both venous and arterial thromboses and often iatrogenic complications (eg, central catheterization). Treatment guidelines for pediatric patients with TE events most often are extrapolated from the literature regarding adults. Options for the manageme
Introduction: Previous studies have shown that the injection of adipose tissue–derived stem cells (ADSCs) into the tunica albuginea (TA) during the active phase of Peyronie's disease (PD) prevents the development of fibrosis. Aim: To investigate, using an animal model, whether local injection of human ADSCs (hADSCs) can alter the degree of fibrosis in the chronic phase of PD. Methods: 27 male, 12-
It is well known that marine fish dynamics relate with climate variability, and predicting future population developments have become increasingly urgent with on-going climate change. One approach in widespread populations is to study how individuals from different parts of the distribution area respond to climate, thereby testing for potential resilience in terms of local adaptions against enviro
Renegotiations: Body, Line, Ethics departs from questions concerning authorship and agency for actors in institutionalised settings and moves towards a discussion on ethics, responsibility and possibilities in the body – text relationship. The question of how bodies can be renegotiated in and by the theatrical line is central to the work. Against a backdrop of previous and other stage productions
PURPOSE: Mutations of PCDH15, the gene encoding protocadherin 15, cause either nonsyndromic deafness DFNB23 or Usher syndrome type 1F (USH1F) in humans and deafness with balance problems in Ames waltzer (av) mice. Persons with USH1 usually begin to exhibit signs of retinitis pigmentosa (RP) in early adolescence, but av mice are reported to have functional retinas. In this study, the auditory, visu
There are excellent guidelines for clinicians to manage venous diseases but few reviews to assess their hemodynamic background. Hemodynamic concepts that evolved in the past have largely remained unchallenged in recent decades, perhaps due to their often complicated nature and in part due to emergence of new diagnostic techniques. Duplex ultrasound scanning and other imaging techniques which evolv
Abstract Purpose: The main purpose with this thesis was to describe the complexities involved when public sector organizations initiate changes in their organizational culture. This research also aims to depict how managers in a public organization interpret the implementation of two separate “shared value systems”, that originates from different parts of the organization. Research design: This th
