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There is strong evidence that tumor growth is not only a result of uncontrolled cell proliferation but also of decreased apoptosis. Caspase-3 is a member of interleukin-1 beta-converting enzyme which is involved in the induction of apoptosis. Data on the expression of caspase-3 in patients with gastric cancer and its association with patient outcome are somewhat contradictory. We aimed to investig
Healthy first-degree relatives with heredity of type 2 diabetes (FH+) are known to have metabolic inflexibility when compared to subjects without heredity for diabetes (FH-). In this study, we aimed to test the hypothesis that FH+ individuals have an impaired response to exercise compared to FH-. 16 FH+ and 19 FH- insulin sensitive men similar in age, VO2peak and BMI completed an exercise interven
Implantation of surgical meshes is a common procedure to increase abdominal wall stability in hernia repair. To improve biocompatibility of the implants, sophisticated in vivo animal models are needed to study inflammation and incorporation of biomaterials. Herein, we have established a new model that allows for the quantitative analysis of host tissue response and vascular ingrowth into surgical
Julian D. Mortenson has written an article for the most recent issue of the American Journal of International Law which he has furnished with the title "The Travaux of Travaux: Is the Vienna Convention Hostile to Drafting History?" The article suggests a reading of Articles 31 and 32 of the 1969 Vienna Convention on the Law of Treaties that is radically different from the one generally assumed. As
Therapeutic antibodies that block the programmed death-1 (PD-1)-programmed death-ligand 1 (PD-L1) pathway can induce robust and durable responses in patients with various cancers, including metastatic urothelial cancer. However, these responses only occur in a subset of patients. Elucidating the determinants of response and resistance is key to improving outcomes and developing new treatment strat
Venous compliance in the legs of aging man has been found to be reduced with decreased blood pooling (capacitance response) in dependent regions, and this might lead to misinterpretations of age-related changes in baroreceptor function during orthostasis. The hemodynamic response to hypovolemic circulatory stress was studied with the aid of lower-body negative pressure (LBNP) of 60 cmH(2)O in 33 h
Avdelningen för ledningsstöd ansvarar för fakultetsövergripande processer inom forskning, utbildning, samverkan, drift och lokaler samt generell myndighetsutövning. Avdelningen ger strategiskt och operativt stöd till institutions- och fakultetsledningar och arbetar med att utveckla effektiva arbetssätt samt samordning inom lednings- och beslutsstöd.
Brevmall APPLICATION FOR ADMISSION TO POSTGRADUATE STUDIES AT THE FACULTY OF SCIENCE Subject for postgraduate studies ref no Personal details Last name, First name Personal reg. no. (yy-mm-dd-xxxx) Address Female Male Postal code, Town/City Telephone number E-mail address Citizenship Swedish Other (specify below) Former last name, if any Education Degree/courses at Lund University Higher education
https://www.science.lu.se/internal/sites/science.lu.se.internal/files/application_admission_postgraduate_studies.pdf - 2026-07-10
A Ph.D. Interview with Alexandra Gabriela Barros Ferreira Alexandra Gabriela Barros Ferreira, a Ph.D. student at Lund University, is set to defend her thesis on Friday, 17 November 2023. Alexandra’s pursuit of scientific discovery has led her to focus on developing innovative strategies to combat cancer. Her research involves direct reprogramming approaches, which function like a Trojan horse, ena
https://www.stemcellcenter.lu.se/phd-interview-alexandra-ferreira - 2026-07-09
We consider the dynamics of a one-dimensional system consisting of dissimilar hardcore interacting (bouncy) random walkers. The walkers' (diffusing particles') friction constants ξ(n), where n labels different bouncy walkers, are drawn from a distribution ϱ(ξ(n)). We provide an approximate analytic solution to this recent single-file problem by combining harmonization and effective medium techniqu
Immature progenitor cells (generated by in vitro propagation) may provide a useful alternative to primary cells (from dissected embryonic tissue) for transplantation if their migratory and proliferative and differentiation properties can be controlled and directed in vivo. In this study E15 murine EGF-responsive progenitor cells were transplanted to the striatum of adult rats. Simultaneously, thes
This study investigates information about the sexual effects of cancer on patients, irrespective of age or diagnosis, in terms of fertility, sexual desire and sexual function. A quantitative study was conducted and the results are based on responses from 106 questionnaires. The results show that 48% of respondents had not received any information in the areas of inquiry. There was a difference bet
Moths of Lobesia botrana (Lepidoptera: Tortricidae) are confronted with different volatiles emitted from the host plant during the different seasons. To test the hypothesis of plasticity of central plant odour processing in moths of different generations in the future, we first investigated the responses of antennal lobe (AL) interneurons of laboratory-reared virgin and mated males and females. We
Non-Hodgkin lymphoma (NHL) remains one of the most common cancers in the US, with survival dependent on the type and stage of disease. B-cell lymphomas account for similar to 85% of all cases of NHL, and are commonly treated with chemotherapy, or monoclonal antibodies (mAbs) that t arget CD20 antigens on the surface of malignant tumors. The use of mAbs, either as single agents or in combination wi
Welcome! INTRODUCTION WEEK 2016 SCHEDULE Congratulations! Not only are you about to start an exciting new chapter of your life at the University of Lund, you’ve also signed up for what might be the most awesome introduction week of all time. Check out the schedule below to see what’s in store! Week 1 Week 2 Monday 22/08: Morning mingle, reception at City Hall and guided tour of Helsingborg. Mornin
https://www.isk.lu.se/en/sites/isk.lu.se.en/files/introductionweek2016schedule.pdf - 2026-07-10
Syftet med nuvarande arbetet är att genomföra en klinisk fallstudie som utvärderar begreppet Dynamisk-ElectroEnhanced Chemotherapy ™ (D-EECT). Tio patienter med plavocellkarcinom, åtta med bröstcancer och fem patienter med var och en som presenterade en annan typ av tumör, infördes i försöken initierade av fem olika cancercentra. Alla patienter fick Bleomycin och 2-3 behandlingstider med IQWave ™ The aim of the present work is to perform a clinical case study evaluating the concept of Dynamic-ElectroEnhanced Chemotherapy™ (D-EECT). Ten patients with squamous cell carcinoma, eight with breast cancer and five patients with each presenting a different type of tumour, were entered in the trials initiated by five different cancer centres. All the patients were given Bleomycin and 2 to 3 treatme
Stroke is one of the leading causes of death and disability, yet the cellular response to the ischemic insult is poorly understood limiting therapeutic options. Brain pericytes are crucial for maintaining blood-brain barrier (BBB) integrity and are known to be one of the first responders to ischemic stroke. The exact timeline of cellular events after stroke, however, remains elusive. Using the per
