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Today, the majority of prostate tumours are detected at early stages with uncertain prognosis. Therefore, we set out to identify early predictive markers of prostate cancer with aggressive progression characteristics. We measured the expression of microRNAs (miRNA) using qRT-PCR in FFPE prostatic tissue samples from a Swedish cohort of 49 patients with prostate cancer and 25 without cancer and fou
Objective To determine the association between concentration of prostate specific antigen (PSA) at age 40-55 and subsequent risk of prostate cancer metastasis and mortality in an unscreened population to evaluate when to start screening for prostate cancer and whether rescreening could be risk stratified. Design Case-control study with 1: 3 matching nested within a highly representative population
A fast 2D motion estimator has been developed and evaluated. The method does not utilize block-matching or iterative solutions and is thus more computationally efficient and suitable for real-time motion estimation over the entire image. The method has been evaluated on 1) phantom measurements and 2) in vivo on the carotid artery wall of 17 subjects, where measurements of the longitudinal displace
The general objective of the research underlying this dissertation was to conduct clinical and basic scientific studies to further elucidate the hemophilia and the coagulation process, with the goal of improving the care of families with these disorders. More specific aims were to evaluate epidemiological, genetic, clinical, and biochemical aspects of the development of inhibitors (antibodies) aga
While the common lymphoid progenitor compartment was originally thought to be a rather homogenous cell population, it has become increasingly clear that this compartment is highly heterogeneous both with regard to phenotypic and functional features. The exploration of this cellular complexity has generated novel molecular insights into regulatory events in lymphoid lineage restriction and provided
Abstract Objective. Prostate cancer antigen 3 in urine (uPCA3) has been shown to perform better than total prostate-specific antigen in serum (tPSA) to predict prostate cancer (PCa) detection. The aim of this study was to validate the diagnostic precision of uPCA3 in a mixed set of patients with no previous history of PCa, including patients with previous negative biopsies. Material and methods. T
IL-5 is a Th2 cytokine which activates eosinophils and is suggested to have an atheroprotective role. Genetic variants in the IL5 locus have been associated with increased risk of CAD and ischemic stroke. In this study we aimed to identify genetic variants associated with IL-5 concentrations and apply a Mendelian randomisation approach to assess IL-5 levels for causal effect on intima-media thickn
Treatment with IgG against the malondialdehyde (MDA)-modified apolipoprotein B-100 epitope p45 reduces atherosclerosis in experimental models. This study investigated the association between p45 IgG autoantibodies and plaque inflammation in subjects with advanced cardiovascular disease.
1 Verksamhetsplan för Socialhögskolan 2017 Antagen av Institutionsstyrelsen 2016-12-14 Denna verksamhetsplan presenterar Socialhögskolans samlade verksamhet utifrån den indelning som görs i budget: grundutbildning, forskarutbildning, forskning och gemensamma verksamheter. Eftersom de huvudsakliga kostnaderna för verksamheten består i personalkostnader och personalen är institutionens viktigaste re
https://www.soch.lu.se/internt/sites/soch.lu.se.internt/files/verksamhetsplan-2017.pdf - 2026-05-11
1 M al m ö A rt A ca de m y 20 14 –2 01 5 M FA 1 B FA 1 & 2 2 M al m ö A rt A ca de m y 20 14 –2 01 5 Masters of Fine Arts – Year 1 Bachelor of Fine Arts – Year 2 Bachelor of Fine Arts – Year 1 3 Master of Fine Arts Year 1 Alice Angeletti Markus Bråten Dick Joakim Hedlund Hanni Kamaly Youngjae Lih Johan Lundqvist Jan Moszumanski Henrique Pavão Marie Raffn Ana Rebordão Tomas Sjögren Daniel Seferian
https://www.khm.lu.se/sites/khm.lu.se/files/yearbook_2015_mfa1_bfa1-2.pdf - 2026-05-11
Microsoft Word - 180507 Instruktion studerandeskyddsombud LU.docx Instruktion för studerandeskyddsombud vid Lunds universitet Allmänt Studerandeskyddsombud företräder studenterna i arbetsmiljöfrågor. Ombuden utses av studenterna, valprocesserna för detta sköts av respektive kår och Lunds Universitets Studentkårer (LUS). Kårerna ansvarar också för att valda studerandeskyddsombud vet vilket/vilka st
https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/180507_instruktion_studerandeskyddsombud_lu2_0.pdf - 2026-05-11
This study introduces silicon substrates with a switchable magnetic contrast layer (MCL) for polarized neutron reflectometry (PNR) experiments at the solid–liquid interface to study soft-matter surface layers. During standard neutron reflectometry (NR) experiments on soft-matter samples, structural and compositional information is obtained by collecting experimental data with different isotopic co
Background: Analysis of how digital breast tomosynthesis (DBT) screening affects consecutive screening performance is important to estimate its future value in screening. Purpose: To evaluate whether DBT contributes to early detection of breast cancer by assessing cancer detection rates (CDRs), including the fraction of invasive cancers and cancer subtypes in consecutive routine digital mammograph
Electromechanical metal oxides, such as piezoceramics, are often incompatible with soft polymers due to their crystallinity requirements, leading to high processing temperatures. This study explores the potential of ceria-based thin films as electromechanical actuators for flexible electronics. Oxygen-deficient fluorites, like cerium oxide, are centrosymmetric nonpiezoelectric crystalline metal ox
Bragg coherent X-ray diffraction imaging (BCDI) has emerged as a powerful technique for strain imaging and morphology reconstruction of nanometre-scale crystals. However, BCDI often suffers from angular distortions that appear during data acquisition, caused by radiation pressure, heating or imperfect scanning stages. This limits the applicability of BCDI, in particular for small crystals and high
Feeling in control of one’s environment and perceiving one’s home as meaningful have been found to be associated with health and well-being among older adults. As longitudinal studies of younger-old adults are lacking, this study aimed to investigate whether this association exists over time among older adults around retirement age. Longitudinal data from a random cohort of community-dwelling olde
Aerosol science is of utmost importance for both climate and public health research, and in recent years X-ray techniques have proven effective tools for aerosol-particle characterization. To date, such methods have often involved the study of particles collected onto a substrate, but a high photon flux may cause radiation damage to such deposited particles and volatile components can potentially
Objectives: Antihistamines have been reported to be linked with less pain in osteoarthritis. We aimed to estimate associations between antihistamine use and three outcomes: prevalent osteoarthritis, current joint pain, and developing osteoarthritis. Methods: We included 25 003 participants of EpiHealth – a cohort of persons aged 45 to 75 from Malmö/Uppsala in Sweden. Participants self-reported the
Detailed numerical simulations are conducted in comparison with experimental results to study the flame structure and burning rate of a steadily burning aluminum droplet in hot steam-dominated environments. The droplet surface temperature, flame temperature, and flame stabilization position are measured along with the droplet burning rate estimated from the droplet size evolution. A numerical mode
