Filetype
Community screening to guide preventive interventions for acute aortic disease has been recommended in high-risk individuals. We sought to prospectively assess risk factors in the general population for aortic dissection (AD) and severe aneurysmal disease in the thoracic and abdominal aorta.
Library and information science (LIS), is a research area marked by theoretical diversity and strong influence from both the developing library profession, as well as other social sciences. During the development of LIS several attempts have been made to define its scientific identity. The definition of what constitutes core, boundaries and the superior identity of LIS is still debated among resea
Barsebäcks kärnkraftverk driftsattes 1975 och den första reaktorn togs ur drift 1999 och den andra 2005. Nedmontering och rivning av kärnkraftverket har inletts och processen beräknas vara klar på 2030-talet. Syftet med detta examensarbete är att kartlägga eventuell radioaktiv kontamination i området runt Barsebäcksverket. Mitt mål är att ta fram en metod för att särskilja bakgrundsstrålning från Background and aim: The Barsebäck nuclear power plant (NPP) units ceased operations in 1999 and 2005. Now the NPP is in the phase of decommissioning, which is a complicated process that will take many years to complete. Radiological characterization of the surrounding area is a part of the decommissioning process. The aim of this thesis was to identify and quantify residual anthropogenic radioacti
The purpose of this report is to implement and compare the two Basel III standard methods on how to calculate the capital requirement for finan- cial institutions, related to counterparty credit risk. The models being the Standardized Approach for Counterparty Credit Risk (SA-CCR) and the Internal Model Method (IMM). The SA-CCR model is a simpler and more standardized model with prescribed methods
Frågan om bevisning utgör en viktig fråga även i skiljeförfaranden. I synnerhet skriftlig bevisning är viktig då den överlag anses vara mer tillförlitlig än muntlig sådan. Det är därför av vikt att part får tillgång till all skriftlig bevisning, även sådan som motpart eller annan kan tänkas inneha. Om dessa dokument frivilligt företes av part eller tredje man uppstår inga problem. Problemen börjar
Are there such things as moral, rights and an inner sense of justice? Do they origin from God or are they something given by nature? If there are such things, should they be a part of the legal system? This essay has drawn its inspiration from this kind of thoughts and how they have been handled through history. The structure of the essay is two-folded. Part one is a historical review of the eme
The Roma people’s isolation has been a major concern for the population in Europe for many years. Programs and legal frameworks are created for the protection for this underprivileged group; however the isolation continues to exist. The purpose of this paper is to explain why many of the measures taken are shown to be inadequate. The outlining and the examination of the history in this matter will
Purpose: The purpose is to describe the Malmö Breast Tomosynthesis Screening Project from the beginning to where we are now, and thoughts for the future. Approach: In two acts, we describe the efforts made by our research group to improve breast cancer screening by introducing digital breast tomosynthesis (DBT), all the way from initial studies to a large prospective population-based screening tri
Operando resonant photoelectron spectroscopy (RPES) combined with modulated chemical excitation revealed the dynamic evolution of Ce3+/Ce4+ redox states at the surface of CeO2 during the CO oxidation reaction. Using alternating CO and O2 pulses as chemically modulated signals, we monitored the surface states in the valence band region, unveiling the evolution of electronic structure during the cat
Using several melanoma proteomics data sets we created a single analysis platform that enables the discovery, knowledge build, and validation of diagnostic, predictive, and prognostic biomarkers at the protein level. Quantitative mass-spectrometry-based proteomic data was obtained from five independent cohorts, including 489 tissue samples from 394 patients with accompanying clinical metadata. We
The decline in areal BMD (aBMD) in men may start as early as age 19, but it is debated whether proximal femoral strength follows the same pattern. We measured FN aBMD in a cross-sectional cohort of 1101 men aged 18-28 yr with two-dimensional DXA. Body height, weight, jump height, grip strength, and maximum knee extension torque muscle strength were measured with standard tests, after which BMI was
Purpose: To achieve the high sensitivity of digital breast tomosynthesis (DBT), a time-consuming reading is necessary. However, synthetic mammography (SM) images, equivalent to digital mammography (DM), can be generated from DBT images. SM is faster to read and might be sufficient in many cases. We investigate using artificial intelligence (AI) to stratify examinations into reading of either SM or
OBJECTIVES: To describe the prevalence of cardiovascular disease (CVD) at the time of diagnosis of adult-onset type 1 (T1D) and type 2 (T2D) diabetes, in a recent cohort and compare to a previous cohort from the same region. Further, to explore factors influencing the prevalence of pre-existing CVD, including age, sex, body mass index (BMI) and C-peptide; in the later cohort also heart failure, hy
Apolipoprotein E4 (ApoE4), the major genetic risk factor for Alzheimer's disease (AD), is vital for understanding cellular processes involved in AD pathogenesis. Evidence implicates endosomes as a central player in AD, where endosomal enlargement in neurons is among the earliest changes in AD. This enlargement was reported to be enhanced in APOE4 carriers. Cells internalize ApoE into endosomes for
Single cell sequencing technologies (scRNA-seq, scATAC-seq, etc.) have revolutionized the study of complex tissues and unique organisms, providing researchers with a much needed species agnostic tool to study biological processes at the cellular level. To date, scRNA-seq technologies are expensive, require sufficient cell quantities, and need biological replicates to avoid batch effects or artifac
Proper arterial versus venous endothelial lineage identity is required to establish a hierarchical network of arteries and veins and prevent the occurrence of life-threatening arteriovenous malformations. The molecular mechanisms that govern arteriovenous lineage specification remain however incompletely understood. Here, we demonstrate that the transcription factor Prdm16 is expressed in arterial
We have investigated the effects of short-term neoadjuvant and long-term androgen deprivation therapies (ADTs) on beta-microseminoprotein (MSMB) and cysteine-rich secretory protein-3 (CRISP3) expression in prostate cancer patients. We also studied if MSMB expression was related to genotype and epigenetic silencing. Using an Affymetrix cDNA microarray analysis, we investigated the expression of MSM
A fast 2D motion estimator has been developed and evaluated. The method does not utilize block-matching or iterative solutions and is thus more computationally efficient and suitable for real-time motion estimation over the entire image. The method has been evaluated on 1) phantom measurements and 2) in vivo on the carotid artery wall of 17 subjects, where measurements of the longitudinal displace
