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Accelerating research on biological aging and mental health : Current challenges and future directions

Aging is associated with complex biological changes that can be accelerated, slowed, or even temporarily reversed by biological and non-biological factors. This article focuses on the link between biological aging, psychological stressors, and mental illness. Rather than comprehensively reviewing this rapidly expanding field, we highlight challenges in this area of research and propose potential s

Gammal misstro mot skådespelaren tar ny form

Teatern och skådespelaren har i olika sammanhang och under olika historiska epoker betraktats med misstroende och fientlighet. Man kan rent av tala om en historisk tradition av antipatier där teaterscenen och skådespelarens förvandlingskonst har misstänkliggjorts i egenskap av moraliska instanser. I denna tradition möts filosofer och religiösa moralister, men också teaterpraktiker med olika agendo

Public awareness of palliative care in Sweden

Objective: The aim of this study was to investigate the awareness of palliative care (PC) in a general Swedish population. Design: We developed an e-survey based on a similar study conducted in Northern Ireland, consisting of 10 questions. Closed questions were primarily analyzed using descriptive statistics. Open questions were subject to inductive qualitative analysis. Subjects: The study utiliz

Photorefractive and Spectroscopic Properties of Pr:LiNbO3

From the ultraviolet induced absorption, we have found a broad blue band and little involvement of Pr ions in ultraviolet illumination. Ultraviolet excited photoluminescence and the excitation spectra for visible emission were also measured in Pr:LiNbO3. We estimated photovoltaic constant and photoconductivity by measuring photovoltaic current and voltage with different boundary conditions. With u

Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac arrest

Background: Anoxic brain injury is the primary cause of death after resuscitation from out-of-hospital cardiac arrest (OHCA) and prognostication is challenging. The aim of this study was to evaluate the potential of two fragments of tau as serum biomarkers for neurological outcome. Methods: Single-center sub-study of 171 patients included in the Target Temperature Management (TTM) Trial randomly a

Hypothermia versus normothermia after out-of-hospital cardiac arrest; the effect on post-intervention serum concentrations of sedatives and analgesics and time to awakening

Background: This study investigated the association of two levels of targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA) with administered doses of sedative and analgesic drugs, serum concentrations, and the effect on time to awakening. Methods: This substudy of the TTM2-trial was conducted at three centers in Sweden, with patients randomized to either hypothermia or

Männen och målningarna : Nationalmuseum som konsekrerande institution 1885–1920

Doktorsavhandlingen ger inblick i en betydelsefull konsekrerande beslutsprocess inom det svenska konstfältet under perioden 1885–1920. Den analyserar de sociala strukturer som bar fram Nationalmuseums inköpsnämnds och museinämnds årliga beslutsförslag till Kungl. Maj:t om vilka oljemålningar, skapade av vid tiden levande svenska konstnärer, som skulle inlemmas i samlingarna och vilka som skulle exThis dissertation examines the Swedish National Museum of Fine Arts (Nationalmuseum) as a consecrating institution of fine art, between 1885 and 1920. A time influenced by major events such as the First World War, Sweden’s industrial revolution and the advent of universal suffrage. During this period, the production and consumption of the Arts was characterised by rivalry between three fractions,

External validation of the CREST model to predict early circulatory-etiology death after out-of-hospital cardiac arrest without initial ST-segment elevation myocardial infarction

Background: The CREST model is a prediction model, quantitating the risk of circulatory-etiology death (CED) after cardiac arrest based on variables available at hospital admission, and intend to guide the triage of comatose patients without ST-segment-elevation myocardial infarction after successful cardiopulmonary resuscitation. This study assessed performance of the CREST model in the Target Te

QREME – Quality requirements management model for supporting decision-making

[Context and motivation] Quality requirements (QRs) are inherently difficult to manage as they are often subjective, context-dependent and hard to fully grasp by various stakeholders. Furthermore, there are many sources that can provide input on important QRs and suitable levels. Responding timely to customer needs and realizing them in product portfolio and product scope decisions remain the main

Bridge Management Based on Bayesian Decision Analysis with Sustainability Considerations

With increasing climate-induced stresses and ageing infrastructure worldwide, integrating sustainability into infrastructure management is essential. Structural Health Monitoring (SHM) systems provide valuable insights for assessing and maintaining the safety and integrity of ageing structures, but their implementation entails significant costs. Resources allocated to SHM could alternatively suppo

Deep Generative Models for Fast Photon Shower Simulation in ATLAS

The need for large-scale production of highly accurate simulated event samples for the extensive physics programme of the ATLAS experiment at the Large Hadron Collider motivates the development of new simulation techniques. Building on the recent success of deep learning algorithms, variational autoencoders and generative adversarial networks are investigated for modelling the response of the cent

Agency and self-organised care experiences in Sweden's Collaborative Housing for the second half of life

In the Swedish context, ‘intergenerational Collaborative Housing’ and ‘Collaborative Housing for the second half of life’ (CH2L), based on the self-work model, were developed in the 1980s and 1990s. The chapter examines how ageing individuals developed caring practices and mutual support strategies in these collective housing forms and how such practices were adapted during the COVID-19 pandemic.

Outcome in adult patients with severe TBI, using a management protocol allowing a cerebral perfusion pressure ≤ 60 mmHg – a retrospective study over 10 years

Background: Current guidelines for the treatment of severe TBI recommend maintaining a cerebral perfusion pressure (CPP) at 60–70 mmHg. In our institution, as well as others, an alternative algorithm—originally named the Lund concept—has been used. This treatment algorithm employs metoprolol and clonidine to limit CPP, accepting levels below 60 mmHg, with the aim of reducing cerebral edema. Previo