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Background: The epidemic of Alzheimer's disease (AD) represents a significant challenge for the health care and social service systems of many developed countries. AD affects both patients and family caregivers, on whom the main burden of care falls, putting them at higher risk of stress, anxiety, mortality and lower quality of life. Evidence remains controversial concerning the effectiveness of p
This article contributes to an understanding of how different institutional contexts produce similar outcomes as regards the employment of migrant workers in care work. It examines how the employment of migrant care workers in both the familial provision of care and the formal provision of care services for older people is shaped, first, by the marketisation of care and, second, by immigration con
BACKGROUND: Pegylated interferon alfa plus ribavirin protocol is currently considered the most efficient hepatitis C treatment. However, no evidence of costs comparison among common viral genotypes has been published.OBJECTIVES: We aimed to assess core drivers of hepatitis C medical care costs and compare cost effectiveness of this treatment among patients infected by hepatitis C virus with genoty
Results of a search for physics beyond the Standard Model in events containing an energetic photon and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. As the number of events observed in data, corresponding to an integrated luminosity of 36.1 fb- 1 of proton–proton collisions at a centre-of-mass energy of 13TeV, is in agreement with the Standard
Background: Lack of a global consensus on the definition of advanced Parkinson’s disease (APD) and considerations for timing of device-aided therapies may result in heterogeneity in care. Objectives: To reach consensus among movement disorder specialists regarding key patient characteristics indicating transition to APD and guiding appropriate use of device-aided therapies in the management of PD
The German federal state of North Rhine-Westphalia (NRW) is home to one of the most important industrial regions in Europe, and is the first German state to have adopted its own Climate Protection Law (CPL). This paper describes the long-term (up to 2050) mitigation scenarios for NRW's main energy-intensive industrial sub-sectors which served to support the implementation of the CPL. It also descr
Background: Aβ pathology is associated with longitudinal changes of brain metabolism, atrophy, and cognition, in cognitively healthy elders. However, Aβ information is usually measured cross-sectionally and dichotomized to classify subjects as Aβ-positive or Aβ-negative, making it difficult to evaluate when brain and cognitive changes occur with respect to emerging Aβ pathology. In this study, we
This Letter presents a search for new resonances with mass larger than 250 GeV, decaying to a Z boson and a photon. The dataset consists of an integrated luminosity of 3.2 fb−1 of pp collisions collected at s=13 TeV with the ATLAS detector at the Large Hadron Collider. The Z bosons are identified through their decays either to charged, light, lepton pairs (e+e−, μ+μ−) or to hadrons. The data are f
Elephant Moraine (EET) 96029 is a CM carbonaceous chondrite regolith breccia with evidence for unusually mild aqueous alteration, a later phase of heating and terrestrial weathering. The presence of phyllosilicates and carbonates within chondrules and the fine-grained matrix indicates that this meteorite was aqueously altered in its parent body. Features showing that water-mediated processing was
Calcite twinning in carbonaceous chondrite meteorites can be used to reconstruct the deformation history and the parent body environment during and/or after aqueous alteration, but the shock pressure threshold at which the twins develop is unknown. Accordingly, the aim of this study is to determine the magnitude of shock pressure that is needed to generate calcite twins. This was done by measuring
Results are reported of a search for new phenomena, such as supersymmetric particle production, that could be observed in high-energy proton-proton collisions. Events with large numbers of jets, together with missing transverse momentum from unobserved particles, are selected. The data analysed were recorded by the ATLAS experiment during 2015 using the 13 TeV centre-of-mass proton-proton collisio
This paper presents a search for massive charged long-lived particles produced in pp collisions at s=13 TeV at the LHC using the ATLAS experiment. The data set used corresponds to an integrated luminosity of 3.2 fb-1. Many extensions of the Standard Model predict the existence of massive charged long-lived particles, such as R-hadrons. These massive particles are expected to be produced with a vel
A search for singly produced vector-like Q quarks, where Q can be either a T quark with charge + 2 / 3 or a Y quark with charge - 4 / 3 , is performed in proton–proton collisions recorded with the ATLAS detector at the LHC. The dataset corresponds to an integrated luminosity of 20.3 fb- 1 and was produced with a centre-of-mass energy of s=8 TeV. This analysis targets Q→ Wb decays where the W boson
Background Late blight (caused by Phytophthora infestans) is a devastating potato disease that has been found to occur earlier in the season over the last decades in Fennoscandia. Up until now the reasons for this change have not been investigated. Possible explanations for this change are climate alterations, changes in potato production or changes in pathogen biology, such as increased fitness o
Bacterial centromeres-also called parS, are cis-acting DNA sequences which, together with the proteins ParA and ParB, are involved in the segregation of chromosomes and plasmids. The specific binding of ParB to parS nucleates the assembly of a large ParB/DNA complex from which ParA-the motor protein, segregates the sister replicons. Closely related families of partition systems, called Bsr, were i
Three episodes of Paleoproterozoic magmatism with distinctively different nature in the Liaoji belt of the Eastern North China Craton are discussed here: the 2200–2140 Ma Liaoji A-type granites, the 2160–2110 Ma Haicheng mafic sills and the ∼1890 Ma Qingchengzi I-type granites. The Mafeng monzogranitic pluton, representative of the Liaoji A-type granites, gives a SIMS U-Pb zircon age of 2181 ± 6 M
A search for W′bosons in events with one lepton (electron or muon) and missing transverse momentum is presented. The search uses 3.2 fb−1of pp collision data collected at s=13 TeV by the ATLAS experiment at the LHC in 2015. The transverse mass distribution is examined and no significant excess of events above the level expected from Standard Model processes is observed. Upper limits on the W′boson
Background For patients with atrial fibrillation, non-vitamin K oral anticoagulants, or NOACs (dabigatran, rivaroxaban, edoxaban, and apixaban) have been proven non-inferior or superior to warfarin in preventing stroke and systemic embolism, and in risk of haemorrhage. In the pivotal NOAC studies, quality of warfarin treatment was poor with mean time in therapeutic range (TTR) 55–65%, compared wit
