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Rationale: There is no consensus on criteria to include in an asthma remission definition in real life. Factors associated with achieving remission after biologic initiation remain poorly understood. Objectives: To quantify the proportion of adults with severe asthma achieving multidomain-defined remission after biologic initiation and identify prebiologic characteristics associated with achieving
Certified randomness guaranteed to be unpredictable by adversaries is central to information security. The fundamental randomness inherent in quantum physics makes certification possible from devices that are only weakly characterized, i.e., requiring little trust in their implementation. It was recently shown that the amount of certifiable randomness can be improved using the so-called entropy ac
ObjectiveTo compare speech outcomes in 4 groups of 5-year-olds with cleft of the hard and soft palate: with Robin sequence without additional conditions (RS−), with Robin sequence with additional conditions (RS+), without Robin sequence with additional conditions (CP+), and without Robin sequence without additional conditions (CP−).DesignRegistry-based cohort study.SettingRegional public care univ
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with a heterogenous clinical picture. This study aimed to link genetic SLE predisposition with relevant clinical manifestations. Method: Datasets best corresponding to the 11 American College of Rheumatology 1982 (ACR-82) classification criteria for SLE in a large, public database (FinnGen consortium, >218,000 individuals) wer
Background: This study aimed to compare the effect on postoperative complications of combined prehabilitation targeting predefined co-existing risky SNAP factors with usual preoperative routines in surgical patients. Methods: This systematic review followed the PRISMA 2020 guideline and the protocol (CRD42022282611). Five databases were searched from inception to November 7, 2022 for randomised co
Background: Chronic low-grade inflammation is a well-known risk factor for coronary heart disease (CHD) and future cardiovascular events. Anti-inflammatory therapy can reduce the risk of ischemic cardiovascular disease (CVD) events following myocardial infarction (MI). However, it remains unknown to what extent inflammation at the time of an acute event predicts long-term outcomes. We explored whe
Objectives. This study aimed to estimate the prevalence of atrial fibrillation (AF) and identify its associated comorbidities in adults aged 45 years and older, using data from the Swedish general population study EpiHealth. Design. In a cross-sectional design, data of health history, lifestyle factors, anthropometric measurement, and 1-lead ECG recordings from participants in the EpiHealth study
The socioeconomic health gradient has widened since the mid-21st century, but the role of childhood neighborhoods remains underexplored. Most neighborhood studies on health are cross-sectional, and longitudinal research is lacking.We analyze how socioeconomic neighborhood conditions in childhood influence cause-specific deaths in adulthood. We use uniquely detailed geocoded longitudinal microdata
The transport sector is responsible for a third of Swedens’ total GHG emissions, where the private cars are a large part of this. Sweden is committed to reducing the emissions from the transport sector with 70 % until the year 2030. Shifting the vehicle fleet to electrical will be one important factor in achieving the goal, but such technical innovation will not be enough. To reach a more sust
The agricultural sector is both affecting and affected by climate change. Future climate is predicted to be warmer and wetter with more weather extremes. This is going to affect the already vulnerable agricultural sector and we need to strengthen our food production and food security. Therefore, agriculture needs to adapt to climate change to prevent negative effects but also to utilize the p
Increased carbon sequestration in agricultural land is an important measure to reduce global warming. Since the soil is a large carbon sink, a small change in the soil organic carbon (SOC) stocks can make a substantial difference to the carbon dioxide content in the atmosphere. An increase in SOC improves the soil health and fertility which in turn gives better yields and a more secure food supply
The degradation of ecosystems and the loss of biodiversity occurs at an alarming rate. This results in an imbalance of ecosystem functions, leading to a loss of ecosystem services. Ecosystem services are benefits which humans can derive from ecosystems and their internal processes, thus vital to preserve from a societal perspective. The purpose of this study was to explore the possibilities for
Donated food is often fully edible, but improper handling can pose risks to food safety. The aim of this study is to investigate volunteers' knowledge of food safety within organizations that handle donated food and to identify areas for improvement without increasing the administrative burden. A qualitative method was used to gain a deeper understanding of volunteers' experiences and perc
There is scientific consensus today on the importance of local climate work. Many studies have investigated the mechanisms behind effective climate work and what makes some cities and large municipalities the frontrunners in driving progressive climate agendas. While this area of local climate work is well researched there is little research about how climate work looks like in small (non-rural) m
AbstractIntroductionWork environments are rapidly changing in Europe, with climate change, the transition to the circular economy, and expansion of work in green jobs among key factors. Research and interventions are urgently needed to promote worker health and well-being. The European Union (EU) INTERCAMBIO project is the first large-scale initiative to systematically assess mental and physical h
