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Colorectal cancer is the third most common cancer type in the western world. in search of new treatment possibilities, the inflammation mediators, know as cysteinyl leukotrienes (CysLTs), have been shown to regulate intestinal epithelial cell survival and proliferation via the CysLT(1)R, and cell differentiation via the CysLT(2)R. These results prompted us to investigate the significance of CysLT(

HUmic-LIke Substances (HULIS) have been identified as major contributors to the organic carbon in atmospheric aerosol. The term "HULIS" is used to describe the organic material found in aerosol particles that resembles the humic organic material in rivers and sea water and in soils. In this study, two sets of filter samples from atmospheric aerosols were collected at different sites. One set of sa

The effects of dyslipidemia on the risk of type 2 diabetes (T2D) and related traits are not clear. We used regression models and 140 lipid-associated genetic variants to estimate associations between circulating HDL-cholesterol, LDL-cholesterol and triglycerides, and T2D and related traits. Each genetic test was corrected for effects of variants on the other two lipid types and surrogates of adipo

Observational epidemiology has made outstanding contributions to the discovery and elucidation of relations between lifestyle factors and common complex diseases such as type 2 diabetes. Recent major advances in the understanding of the human genetics of this disease have inspired studies that seek to determine whether the risk conveyed by bona fide risk loci might be modified by lifestyle factors

The generation of toxic oligomers during the aggregation of the amyloid-beta (A beta) peptide A beta 42 into amyloid fibrils and plaques has emerged as a central feature of the onset and progression of Alzheimer's disease, but the molecular pathways that control pathological aggregation have proved challenging to identify. Here, we use a combination of kinetic studies, selective radiolabeling expe

The cellular hallmarks of Parkinson's disease (PD) are the loss of nigral dopaminergic neurons and the formation of α-synuclein-enriched Lewy bodies and Lewy neurites in the remaining neurons. Based on the topographic distribution of Lewy bodies established after autopsy of brains from PD patients, Braak and coworkers hypothesized that Lewy pathology primes in the enteric nervous system and spread

Chronic pulmonary disease is a recognized risk factor for invasive pneumococcal disease (IPD). However, previous studies have often not been large enough to allow detailed analyses of less prevalent pulmonary diseases, and findings regarding case fatality have been inconsistent. We examined the associations between an underlying pulmonary disease and IPD, and the impact of these diseases on the ca

The consumption of meat and other foods of animal origin is a risk factor for several types of cancer, but the results for lymphomas are inconclusive. Therefore, we examined these associations among 411,097 participants of the European Prospective Investigation into Cancer and Nutrition. During a median follow-up of 8.5 years, 1,334 lymphomas (1,267 non-Hodgkin lymphoma (NHL) and 67 Hodgkin lympho

Professor Contact details Email: helena [dot] alexanderson [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageHelena Alexandersons profile in Lund University research portalPersonal website:https://www.geologi.lu.se/helena-alexandersonAs a Quaternary geologist my main interest is to learn more about what has occurred during the ic

https://www.geology.lu.se/helena-alexanderson - 2026-07-08

Professor Contact details Email: raimund [dot] muscheler [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageRaimund Muschelers profile in Lund University research portalOther affiliations Member of Strategic Research Area BECC: Biodiversity and Ecosystem services in a Changing Climate Member of Strategic Research Area MERGE: ModEl

https://www.geology.lu.se/raimund-muscheler - 2026-07-08

Professor Contact details Email: leif [dot] lonnblad [at] fysik [dot] lu [dot] se Phone: +46 46 222 77 80Organisation Particle and nuclear physics Visiting address: Sölvegatan 14A, Lund Room number: K233 Service point: 14 WebpageLeif Lönnblads profile in Lund University research portalResearchQCD Phenomenology and Monte Carlo Event Generators.TeachingTheoretical Particle Physics (FYTN18) and (Expl

https://www.particle-nuclear.lu.se/leif-lonnblad - 2026-07-08

Professor Contact details Email: kristina [dot] stenstrom [at] fysik [dot] lu [dot] se Phone: +46 46 222 76 43Organisation Particle and nuclear physics Visiting address: Sölvegatan 14, Lund Room number: K345 Service point: 14 WebpageKristina Stenströms profile in Lund University research portalOther affiliations Member of Strategic Research Area MERGE: ModElling the Regional and Global Earth syste

https://www.particle-nuclear.lu.se/kristina-stenstrom - 2026-07-08

Professor Contact details Email: su_mi [dot] dahlgaard-park [at] ses [dot] lu [dot] se Phone: +46 42 35 66 47Organisation Department of Service Studies Room number: E327 WebpageSu Mi Dahlgaard-Parks profile in Lund University research portalSu Mi Dahlgaard-Park is a professor. Her research and teaching areas are Organization theory, Human resource management (HRM), Learning and knowledge managemen

https://www.ses.lu.se/en/su-mi-dahlgaard-park - 2026-07-08

The performance of six custom-built Hygrocopicity-Tandem Differential Mobility Analyser (H-TDMA) systems was investigated in the frame of an international calibration and intercomparison workshop held in Leipzig, February 2006. The goal of the workshop was to harmonise H-TDMA measurements and develop recommendations for atmospheric measurements and their data evaluation. The H-TDMA systems were co

Renal function deteriorates with age, but a few studies have addressed this longitudinally in elderly women. Our objective was, using 5 estimated glomerular filtration rates (eGFR)-equations, to evaluate changes in renal function and association with adverse outcomes for a decade in 75-year-old women.

The ever-growing demand on high-performance electronics has generated transistors with very impressive figures of merit. The continued scaling of the supply voltage of field-effect transistors, such as tunnel field-effect transistors (TFETs), requires the implementation of advanced transistor architectures including FinFETs and nanowire devices. Moreover, integration of novel materials with high e

Serum-mediated phagocytosis of antibody- and complement-opsonized necrotic cell material (NCM) by polymorphonuclear leukocytes can be quantified by using a flow cytometry–based assay. The phagocytosis of necrotic cell material (PNC) assay parallels the well-known lupus erythematosus cell test. In this study, we aimed to investigate the diagnostic accuracy of the assay and the relationship with cli