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The small leucine-rich proteoglycans fibromodulin and lumican are functionally related extracellular matrix proteins involved in the regulation of collagen fiber formation. Fibromodulin-deficient apolipoprotein E-null mice have decreased vascular retention of lipids and reduced development of atherosclerosis suggesting that fibromodulin may influence the disease process. The aim of the present stu
Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, S
Background: Childhood cancer predisposition (ChiCaP) syndromes are increasingly recognized as contributing factors to childhood cancer development. Yet, due to variable availability of germline testing, many children with ChiCaP might go undetected today. We report results from the nationwide and prospective ChiCaP study that investigated diagnostic yield and clinical impact of integrating germlin
Over the last years metal halide perovskites have demonstrated remarkable potential for integration in light emitting devices. Heterostructures allow for tunable bandgap depending on the local anion composition, crucial for optoelectronic devices, but local structural effects of anion exchange in single crystals is not fully understood. Here, we investigate how the anion exchange of CsPbBr3 nanowi
Transitioning to low-input agricultural systems such as organic farming has been acknowledged as a way to mitigate negative effects of agriculture on biodiversity. However, the speed, magnitude and context dependence of biodiversity recovery after converting to organic farming remain uncertain. In this study, we explored the response of plant communities to time since transition to organic farming
BACKGROUND: Polycystic ovary syndrome (PCOS) has previously been associated with several comorbidities that may have shared genetic, epigenetic, developmental or environmental origins. PCOS may be influenced by prenatal androgen excess, poor intrauterine or childhood environmental factors, childhood obesity and learned health risk behaviors. We analyzed the association between PCOS and several rel
Microsoft Word - Höög Manuscript.doc 1 The Philosophers on the Market Square. Philosophical Modernism from Vienna to Uppsala Victoria Höög Department of Philosophy, Lund University Victoria.Hoog@fil.lu.se ABSTRACT: The logical empiricists in Vienna and their Swedish counterparts in Uppsala shared a scientific ethos that underlined the philosophical academics as representatives for universalism,
https://www.fil.lu.se/hommageawlodek/site/papper/HoogVictoria.pdf - 2026-07-24
Background: Pro-neurotensin (pro-NT) is the stable circulating precursor of neurotensin (NT), a neuropeptide expressed mainly in the central nervous system and small intestine that regulates key physiological processes like fatty acid absorption in the gut and suppresses appetite via central mechanisms. Studies in NT-deficient mice and humans implicate NT in obesity and insulin resistance, highlig
This work investigates the cryogenic performance of InAs-based vertical nanowire ferroelectric field-effect transistors (VNW-FeFETs) with hafnium zirconium oxide (HZO) as the ferroelectric gate dielectric. Measurements at 300 K and 14 K reveal a 25% increase in memory window, from 560 mV at room temperature to 700 mV at 14 K, indicating enhanced polarization stability at low temperatures while als
Supercrystals of lead-halide perovskite nanocrystals combine the semiconducting properties of bulk perovskites with quantum confinement effects and extend them to the macroscopic scale. Supercrystals assembled via a two-layer phase diffusion process using an acetonitrile antisolvent were recently shown to be unusually robust. We investigate how the acetonitrile-assisted self-assembly process influ
Infective endocarditis (IE) is most often caused by alpha-hemolytic streptococci or Staphylococcus aureus and is characterized by the presence of vegetations on the heart valves. Here we present a case of IE caused by Streptococcus pyogenes, a distinctly uncommon IE-pathogen, where no vegetations could be visualized on repeated echocardiography. Diagnosis was instead evident from septic embolizati
Aim: To model the long-term cost-effectiveness of scaling up two prevention interventions against type 2 diabetes mellitus (T2DM), i.e. community mobilisation through participatory learning and action (PLA) and mHealth mobile phone messaging, implemented in rural Bangladesh as part of the “DMagic” trial. Methods: A health-economic Markov model of the three-arm, cluster-randomised controlled DMagic
Hyperbolic phonon polaritons - hybridized modes arising from the ultrastrong coupling of infrared light to strongly anisotropic lattice vibrations in uniaxial or biaxial polar crystals - enable to confine light to the nanoscale with low losses and high directionality. In even lower symmetry materials, such as monoclinic (Formula presented.) -Ga2O3 (bGO), hyperbolic shear polaritons (HShPs) further
Aims: Testing insulin resistance could help improve physician assessment of patients’ risk of prediabetes or type 2 diabetes (T2D), even among normoglycemic individuals. Methods: The longitudinal study followed 16,333 normoglycemic participants in a nation-wide employer-sponsored health assessment program starting in August 2020 with a median follow-up time of 2.9 years for incident prediabetes or
ObjectivesTo compare head acceleration between blind football players and non-disabled football players, and between anticipated and unanticipated conditions in blind football players.DesignLaboratory-based exploratory study.MethodsParticipants were ten football players (five blind football, five non-disabled; 80% female). Standardized head perturbations were applied in flexion, extension, lateral
Spectroscopic studies of energy transport through the photosynthetic apparatus have been crucial to expanding our understanding of biological energy conversion. Correlating spectroscopic information to the electronic structure and function in these complex systems remains highly challenging, however. While cryogenic experimental conditions help in improving the effective spectral resolution and sa
The concept of quasicrystal approximants is best pursued with reference to the quasicrystals themselves. This makes the classification of approximants into classes congruent to those for quasicrystals useful, that is, axial and icosahedral. As noted by several authors, work on approximants has come full circle; the initial interest in approximants grew out of a desire to understand particularly th
Objective: Interstitial lung disease (ILD) can occur in association with antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV-ILD) or as an isolated entity with positive ANCA (ANCA-ILD). However, data on the epidemiology and outcomes of these conditions remain limited. Methods: A European multicenter retrospective study encompassed patients with AAV-ILD or ANCA-ILD. Baseline and s
