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Cardiovascular (CVD) is one of the most common causes of mortality. Apart from known causal risk factors such as smoking, obesity, dyslipidaemia and hypertension, chronic psychological stress has been suggested as a possible independent risk marker, also because the CVD burden follows a social gradient. Another self-reported variable is self-rated health (SRH) which in many studies has ben shown t
The purpose of this study is to explore the lived experience of sexuality for people with physical disabilities using formal personal assistance services in Sweden, from their own perspective. This is analyzed in relation to the aims of personal assistance services according to Swedish law, which states that they should be framed in terms of autonomy, integrity and self-determination making it pos
Monoclonal antibodies ofatumumab (anti-CD20) and alemtuzumab (anti-CD52) which are approved for usage in patients with chronic lymphocytic leukemia (CLL), efficiently activate the classical complement pathway. However complement is an exhaustible component and high doses of its activators may deplete complement-dependent cytotoxicity (CDC) potential, thus reducing the effect of repeated mAb dosing
A Circular Economy (CE) can help to achieve the sustainable development goal of responsible consumption and production. Product policies, in turn, can support CE objectives by promoting reuse of products, recycling of materials, and providing ecodesign incentives for more durable products. This thesis examined the role of product policies in meeting CE objectives in the EU, with specific focus on
Background: Primary indication for catheter ablation of atrial fibrillation (AF) is to reduce symptoms and improve health-related quality of life (HRQoL). There are data showing differences between the genders and between younger and older patients. To evaluate this, we studied a large Scandinavian cohort of patients referred for catheter ablation of AF. Methods: Consecutive patients filled out th
The result of a search for the pair production of the lightest supersymmetric partner of the bottom quark (b˜ 1) using 139 fb−1 of proton-proton data collected at s = 13 TeV by the ATLAS detector is reported. In the supersymmetric scenarios considered both of the bottom-squarks decay into a b-quark and the second-lightest neutralino, b˜1→b+χ˜20. Each χ˜20 is assumed to subsequently decay with 100%
Background: The role of antiarrhythmic drugs for atrial fibrillation/atrial flutter (AF/AFL) after catheter ablation is not well established. Hypothesis: We hypothesized that changing the myocardial substrate by ablation may alter the responsiveness to dronedarone. Methods: We assessed the efficacy and safety of dronedarone in the treatment of paroxysmal/persistent atrial fibrillation/atrial flutt
Dermal substitutes are of major importance in treating full thickness skin defects. They come in a variety of materials manufactured into various forms, such as films, hydrocolloids, hydrogels, sponges, membranes, and electrospun micro- and nanofibers. Bioactive dermal substitutes act in wound healing either by delivery of bioactive compounds or by being constructed from materials having endogenou
BACKGROUND: Compared to the general population, patients with alcohol and drug addiction have an increased risk of additional hazardous lifestyles and suffer from more chronic diseases, adding to their already significantly higher morbidity and mortality. The objective of this study was to test the efficacy of the Very Integrated Program (VIP) on treatment and health outcomes for patients diagnose
The aim of this study was to explore how consequences from a university-wide partnership unfolded at various levels within a university and induced intra-organizational dynamics. This was achieved via an in-depth investigation of “The Bridge,” a collaborative partnership between the young mid-range Swedish Linnaeus University (“Average Joe”) and the home furnishing retail giant IKEA, which despite
Objectives: The primary aim was to find out whether a computer-assisted reading intervention program with a phonic approach can affect event-related (ERPs) and mismatch negativity (MMN) in hearing impaired (HI) children using cochlear implants (CIs). Methods: This study involved a test group of 15 HI children with CIs and a control group of 14 normal hearing (NH) children. The children were 4 year
The recent clinical trial (DAWN) suggests that recanalization treatment may be beneficial up to 24 h after stroke onset, thus re-opening avenues for development of new therapeutic strategies. Unfortunately, there is a continuous failure of drugs in clinical trials and one of the major reasons proposed for this translational roadblock is the animal models. Therefore, the purpose of this study was t
Background: Telephone nursing in primary healthcare has been suggested as a solution to the increased demand for easy access to healthcare, increased number of patients with complex problems, and lack of general practitioners. Registered nurses' assessments may also be of great importance for antibiotic prescriptions according to guidelines. The aim of this study was to describe registered nurses'
A search is presented for four-top-quark production using an integrated luminosity of 139 fb- 1 of proton–proton collision data at a centre-of-mass energy of 13TeV collected by the ATLAS detector at the LHC. Events are selected if they contain a same-sign lepton pair or at least three leptons (electrons or muons). Jet multiplicity, jet flavour and event kinematics are used to separate signal from
A search is presented for new phenomena in events characterised by high jet multiplicity, no leptons (electrons or muons), and four or more jets originating from the fragmentation of b-quarks (b-jets). The search uses 139fb-1 of s = 13 TeV proton–proton collision data collected by the ATLAS experiment at the Large Hadron Collider during Run 2. The dominant Standard Model background originates from
Differential cross-section measurements are presented for the electroweak production of two jets in association with a Z boson. These measurements are sensitive to the vector-boson fusion production mechanism and provide a fundamental test of the gauge structure of the Standard Model. The analysis is performed using proton–proton collision data collected by ATLAS at s=13TeV and with an integrated
The minimization of a functional composed of a nonsmooth and nonadditive regularization term and a combined L1 and L2 data-fidelity term is proposed. It is shown analytically and numerically that the new model has noticeable advantages over popular models in image processing tasks. For the numerical minimization of the new objective, subspace correction methods are introduced which guarantee the c
