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Engineering of pyranose 2-oxidase: Improvement for biofuel cell and food applications through semi-rational protein design
Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac
Functional text geometry: The essentials of Perspective Text Analysis
The molecular basis of human igg-mediated enhancement of C4b-binding protein recruitment to group a streptococcus
Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.
“Self-created person-centred care” – a new notion in eldercare services?
BackgroundDespite the fact that eldercare services are organizationally part of social work in Sweden, the social work practice is disappearing and older people are expected to take the responsibility for their own well-being. In this context, they have to create their own sense of meaningfulness in their everyday life, despite being subject to social care services.Methods As part of a research pr