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Osteoarthritis is a chronic degenerative joint disease, and a rapidly growing cause of musculoskeletal disability, chronic pain, and reduced quality of life in an ageing European population. Our aims are to gain novel insights into osteoarthritis - its etiology, occurrence, natural history, treatments, prediction, disease monitoring, and disease burden - to allow for better care, decision making,

Norma Research Programme är en tvärvetenskaplig forskningsmiljö vid den Juridiska fakulteten, och ett forskningscentrum knutet till the Labour Law Research Network (LLRN). Fokus ligger på den rättsliga regleringen av vardagsliv och social integration på nationell, EU och internationell nivå, och på arbetsmarknad, social välfärd, åldrande befolkning, och familj. Verksamheten innefattar forskning i The Norma Research Programme is an interdisciplinary research environment at the Faculty of Law, and a research centre affiliated with the Labour Law Research Network (LLRN). The focus is on the legal regulation of everyday life and social integration at national, EU, and international level, and on labour markets, social welfare, ageing societies, and families. The research environment includes a

Lars Rönnstrand är forskargruppsledare för den här forskargruppenLars Rönnstrand is Research Group Leader for this research group

Under de senaste 100 åren har vi successivt minskat vår dagliga fysiska aktivitet. Eftersom vi är mindre vältränade, svagare och mer överviktiga har benägenheten att drabbas av sjukdomar som diabetes och hjärt- och kärlsjukdomar ökat. WHO rapporterar att 25% av vuxna inte uppfyller de globala rekommenderade nivåerna av fysisk aktivitet. Vår forskningsenhet är intresserad av att lära sig hur genetiDuring the last 100 years, we have gradually reduced our daily physical activity. As less fit, weaker, and fatter, we have become more prone to diseases like diabetes and cardiovascular disease. The WHO reports that one in four adults do not meet the global recommended levels of physical activity. Our research unit is interested in learning how genetic variation influences skeletal muscle function

Lungcancer är en vanlig tumörsjukdom med dåliga behandlingsresultat och den cancerform som skördar flest liv i Sverige och globalt. Rökning är den starkaste riskfaktorn för lungcancer men 10-15% av patienterna har aldrig rökt. Lungcancer är en heterogen sjukdom på molekylär nivå. För att förbättra diagnostiken, behandlingen och prognosen i lungcancer behövs en bättre förståelse av tumörspecifika fLung cancer, the leading cause of cancer death, is divided into histological subtypes with large differences in molecular alterations, clinical presentation, and patient outcome. By a combined clinical and molecular approach we focus on improving the molecular understanding of lung cancer and translate research findings into a clinical diagnostics. By characterization of the genomic, transcriptio

Epidemiology is the study of the distribution of diseases and disease promoting factors in the population. The cardiovascular epidemiology research group focuses on studies of cerebrovascular diseases (stroke) and heart diseases, such as myocardial infarction, heart failure or atrial fibrillation. The research is performed in well characterized population-based cohorts, with extensive information

We aim to identify novel interventions for prevention and treatment of diabetes-related cardiovascular disease (CVD). Our strategy is to identify genetic, endocrine and metabolic disturbances in humans which are causally related to disease development and are detectable many years before disease presents. We then test in both animals and in human intervention studies if manipulation of such molecu